Afleveringen
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You’ve probably tried everything to sleep better. Magnesium. Melatonin. Blackout curtains. Maybe even expensive sleep gadgets. But what if the real reason your sleep feels broken has nothing to do with any of those things?
In this video, Dave Asprey explains a hidden biological process that controls whether your body stays in stress mode at night… or finally switches into deep recovery mode. He breaks down why so many people wake up exhausted, why cortisol stays elevated while you sleep, and why your body may never fully enter repair mode even if you’re technically asleep.
You’ll learn how one overlooked habit affects your brain, metabolism, recovery, heart rate, and overnight repair systems, plus the surprising research that showed dramatic changes in sleep quality from a single adjustment. Once you understand this mechanism, you’ll never look at sleep the same way again.
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I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a waste of money, and the exact stack that delivers hours of clean focus without the afternoon crash.
The shift is simple: focus isn't a willpower problem. It's an energy production problem inside your brain. Once you fuel it at the cellular level, deep focus stops being a struggle and becomes the default state.
Thank you to our sponsors!
PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.Viome | Check it out at viome.com and use code 16DAVE for 16% off. It’s time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE00:00 – Trailer
00:53 – Sleep Environment Matters
03:44 – Red Light Bulbs
04:50 – Blackout Curtains
05:16 – Light-Blocking Glasses
07:16 – Morning Supplement Stack
07:41 – Creatine for the Brain
11:48 – MCT Oil Fuel
13:06 – Cellular Cleanup (Autophagy)
15:12 – Magnesium for Sleep
16:56 – Full Stack Recap
18:26 – Biohacking Is Accessibl
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/
TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Artificial Sweeteners & Cognitive Decline, Myosteatosis on Coronary CT, Merck's Oral PCSK9 Inhibitor, Cyclospora Outbreak, Gut-Brain Synchronization, and the Banana Smoothie Mistake Explained
Artificial Sweeteners Linked To 62% Faster Cognitive Decline In Landmark Brazilian Study
A study tracking more than 12,700 adults (average age 52) over eight years found that people consuming the most artificial and low-calorie sweeteners, roughly 191 mg a day, about what's in a single can of diet soda, showed cognitive decline 62% faster than the lowest-intake group, equivalent to 1.6 extra years of brain aging, with memory hit hardest. Six of the seven sweeteners tested, including aspartame, saccharin, and acesulfame K, were linked to faster decline; tagatose was the lone exception. Researchers point to gut-microbiome disruption, altered glucose and insulin signaling, and possible direct neuronal effects as plausible mechanisms. Host Dave Asprey breaks down why a dose this small was enough to move the curve, why tagatose deserves more scrutiny before being called "safe," and where diet products' short-term weight-loss marketing conveniently ignores the long-term cost to your brain.
Source:
https://www.inc.com/kevin-haynes/study-links-cognitive-decline-to-surprisingly-small-daily-amount-of-artificial-sweeteners/91376522
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AI Analysis Of 1,722 Heart Scans Finds Muscle Quality Predicts Heart Attacks Independent Of Calcium Score
Using data from the SCOT-HEART trial, a University of Edinburgh team ran an AI model against ten years of coronary CT angiogram scans, measuring skeletal muscle attenuation, a marker of myosteatosis, or fat infiltration into muscle tissue. Every 10-point increase in muscle density corresponded to a 31% lower heart attack risk and 39% lower all-cause mortality over the following decade, and critically, this held independent of coronary calcium score, the current gold-standard risk marker. The same low-density-muscle patients also showed higher lung attenuation, lower liver attenuation, and more torso fat volume, a pattern consistent with systemic insulin resistance rather than a muscle-specific issue. Host Dave Asprey unpacks why calcium score isn't capturing the full risk picture, why myosteatosis is really a readout of whole-body insulin sensitivity, and what he'd add to a routine workup on top of a calcium score.
Source:
https://www.theguardian.com/science/2026/jun/30/strong-chest-back-less-likely-heart-attack-analysis
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FDA Approves First Oral PCSK9 Inhibitor, Cutting LDL By Up To 60% Without Injections
Merck's enlicitide (brand name Lipfendra) is now FDA-approved as the first once-daily oral PCSK9 inhibitor, lowering LDL cholesterol by up to 60% in a phase 3 trial of 2,912 patients, routinely bringing levels down to 50-60 mg/dL. It works by blocking PCSK9, a liver protein that tags LDL receptors for destruction, the same target as injectable drugs like Repatha and Praluent, which have shown roughly 20% reductions in heart attacks and strokes in high-risk patients. Lipfendra is priced at $315 for a 30-day supply, with no excess side effects reported versus placebo over six months, though long-term outcome data is still pending. Host Dave Asprey explains why crushing total LDL without checking ApoB, LDL particle number, or oxidized LDL is optimizing the wrong variable, and what he'd want on his labs before considering a drug like this.
Sources:
https://www.nytimes.com/2026/07/16/science/the-fda-approves-a-new-pill-to-slash-cholesterol-levels.html
https://www.cnbc.com/2026/07/16/mercks-cholesterol-pill-gets-us-fda-approval.html
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Cyclospora Outbreak Tied To Taylor Farms Lettuce Spreads To 34 States, Prompts Nationwide Recall
Federal investigators have linked a multistate cyclosporiasis outbreak to shredded iceberg lettuce from Taylor Farms de Mexico, with Michigan alone logging over 5,000 cases and 100+ hospitalizations, much of it traced to lettuce used at Taco Bell. Taylor Farms has recalled all iceberg lettuce sourced from central Mexico, and Walmart has pulled Marketside Iceberg Salad and Marketside Shredded Lettuce with specific date codes across 27 states. Cyclospora spreads through fecal contamination and causes weeks of watery, explosive diarrhea if untreated; washing doesn't reliably eliminate it, since the parasite requires heat above 158°F to inactivate. Host Dave Asprey explains why pre-washed, pre-cut bagged greens remain a recurring contamination risk no matter what the label claims, and connects the outbreak's gut damage to lingering gut-brain consequences long after symptoms resolve.
Sources:
https://www.usatoday.com/story/news/health/2026/07/18/taylor-farms-shredded-lettuce-sample-cyclospora/90969103007/
https://www.fda.gov/food/outbreaks-foodborne-illness/investigation-5-state-outbreak-cyclospora-illnesses-iceberg-lettuce-july-2026
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New Research Links Excessive Gut-Brain Synchronization To Anxiety And Depression
Emerging research on the enteric nervous system, which contains over 100 million neurons and sends more signals to the brain than it receives, finds that when the gut's electrical rhythm synchronizes too tightly with the brain's, that over-coupling correlates with higher rates of anxiety and depression. The gut communicates with the brain through the vagus nerve, hormones, and immune signaling, and dysbiosis or ENS dysfunction has separately been linked to mood disorders in both human and animal studies. Host Dave Asprey breaks down why the goal isn't maximum gut-brain connection but the right kind of connection, questions whether the coupling is driving the anxiety or the anxiety is driving the coupling, and makes the case for treating mood from the gut up instead of the brain down.
Source:
https://refractor.io/medical/enteric-nervous-system-brain-link-mental-health/
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Rhonda Patrick Explains Why She Never Adds Bananas To Her Berry Smoothies
Rhonda Patrick has been telling audiences she skips bananas in her berry smoothies because of polyphenol oxidase, an enzyme in bananas that degrades the polyphenols in blueberries linked to improved cognition and vascular health, based on in-vitro and food chemistry data. She now builds her smoothies on an avocado base instead, and notes that vitamin C from citrus can partially inhibit the enzyme for anyone unwilling to drop the banana. Host Dave Asprey weighs in on the gap between lab chemistry and clinical outcome data, why that gap doesn't make the mechanism any less real, and why this is a low-cost swap worth making even without a human trial behind it.
Sources:
https://www.reddit.com/r/Biohackers/comments/1v2jbib/dr_rhonda_patrick_i_dont_add_bananas_to_my/
https://www.foundmyfitness.com/episodes/polyphenol-oxidase-bananas-smoothies
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This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insight into a sweetener risk hiding in everyday diet products, a heart attack predictor buried inside routine CT scans, the tradeoffs of a new cholesterol drug, a produce recall worth paying attention to, the science behind gut-driven anxiety, and a smoothie mistake that's quietly undercutting your polyphenol intake. Host Dave Asprey connects clinical research, cohort data, and food chemistry into practical frameworks for protecting brain health, cardiovascular health, and gut-brain resilience.
New episodes every Tuesday, Thursday, Friday, and Sunday.
Keywords: artificial sweeteners cognitive decline, aspartame brain aging, tagatose safety, diet soda memory loss, myosteatosis coronary CT, skeletal muscle attenuation heart attack, SCOT-HEART trial, coronary calcium score insulin resistance, enlicitide Lipfendra FDA approval, oral PCSK9 inhibitor, LDL particle number ApoB, cyclospora outbreak 2026, Taylor Farms lettuce recall, cyclosporiasis symptoms treatment, enteric nervous system anxiety, gut brain synchronization, vagus nerve mental health, Rhonda Patrick polyphenol oxidase, banana blueberry smoothie mistake, biohacking news 2026, Dave Asprey, The Human Upgrade
Thank you to our sponsors!
- Suppgrade Labs | Get real restorative sleep with Quiet Mode. Use code DAVE15 at shopsuppgradelabs.com.
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Resources:
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Intro
00:19 – Story 1: Artificial Sweeteners
02:05 – Story 2: Muscle Fat & Heart Risk
04:36 – Story 3: PCSK9 Cholesterol Pill
06:27 – Story 4: Cyclospora Lettuce Outbreak
07:56 – Story 5; Gut-Brain Axis & Anxiety
09:29 – Story 6: Banana vs. Blueberry
11:08 – Predictions for Next 5 Years
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Fix Leaky Gut, Boost Testosterone & Slash Endotoxins with Spore-Based Probiotics | Kiran Krishnan
Your bad gut bacteria might be the reason your testosterone, your immune system, and even your sperm count are struggling, and most probiotics never survive long enough to fix it. This episode reveals which strains actually make it through your stomach acid alive, and what happens once they do.
Go To JustThriveHealth.com/asprey for a free 90 day supply of bitters with your next subscription.
Host Dave Asprey sits down with research microbiologist Kiran Krishnan, co-founder of Microbiome Labs, the leading microbiome therapeutics brand among healthcare professionals. He has published multiple peer-reviewed studies, holds global patents, and has spent 20 years building companies focused on the science of the microbiome. His work centers on spore-based probiotics, the rare strains proven to survive the stomach's brutal acidity and actually rebuild the gut from the inside out.
Kiran and Dave break down why 98 percent of conventional probiotics die before they ever reach your gut, and why spore-forming bacteria are different. They dig into the "gelding effect," the well-documented pathway where endotoxins from bad gut bacteria shut down testosterone production and drive up cortisol, and how fixing your microbiome can reverse it. They cover the connection between endotoxemia and nearly every major marker of aging, metabolism, and inflammation, why butyrate acts like a natural GLP-1 for fat loss, how Akkermansia can upregulate mitochondria and improve blood sugar control, and the surprising role vitamin K2 plays in bone density and functional medicine. This is biohacking at the cellular level, using ancient biology, fasting-adjacent metabolic pathways, and precision supplementation to optimize human performance from the gut up.
You'll Learn:
Why 98 percent of probiotics die in your stomach before they ever work What the "gelding effect" is and how gut bacteria can shut down testosterone How endotoxins drive inflammation, cortisol, and accelerated aging Why butyrate functions like a natural, low-cost alternative to GLP-1 drugs How Akkermansia improves mitochondrial function and blood sugar control The overlooked link between your microbiome and vitamin K2 production Why spore-based probiotics can survive gastric acid when most others cannot How 90 days of gut repair can measurably reduce circulating endotoxinsKeywords: best probiotics that survive stomach acid, spore based probiotics benefits, gelding effect testosterone, endotoxins and testosterone, how to lower endotoxins, LPS gut bacteria, Akkermansia GLP-1 natural, gut bacteria and belly fat, vitamin K2 bone density, Kiran Krishnan microbiologist, Just Thrive probiotic, leaky gut symptoms, microbiome and testosterone, fecal transplant benefits, Dave Asprey, biohacking, longevity
Resources:
• Go To JustThriveHealth.com/asprey for a free 90 day supply of bitters with your next subscription
• Learn More About All Of Just Thrive’s Offerings At: https://justthrivehealth.com/
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15?
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Thank you to our sponsors!
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- BodyHealth | Visit BodyHealth.com and use code DAVE20 for 20% off your first purchase.
- Redmond Real - Leaf Toothpaste | Go to https://redmond.com/asprey and use code ASPREY for 15% off your first order.
- Show notes - ELITE Performance Coaching | If you’d like to discover where you may be addicted to struggle, allergic to success, and what may be standing between you and your next breakthrough, visit FastestChange.com
Timestamps:
00:00 – Trailer
00:38 – Kiran Intro
02:01 – Stomach Acid & Probiotics
05:25 – Fauci & Spore Bacteria
13:58 – Losing Gut Diversity
19:01 – How Butyrate Is Made
22:11 – Dave's Personal Stack
24:00 – Quorum Sensing
31:26 – Endotoxins Explained
37:13 – Charcoal & Binders
39:41 – SIBO & Gut Bacteria
45:03 – Discovering Vitamin K2
49:33 – Gelding Effect & Testosterone
54:51 – Akkermansia & Weight Loss
01:02:17 – Role of Bitters
01:04:47 – Just Thrive Gift
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Visceral fat, subcutaneous fat, Prenuvo MRI scans, and the truth about belly fat
Your gut and your face are telling on you. This episode reveals why the fat under your skin might be protecting you while the fat around your organs is quietly wrecking your metabolism, heart, and longevity, and exactly what to do about the difference.
Get $300 off your next Prenuvo MRI scan: https://prenuvo.com/?discount=Dave
Host Dave Asprey sits down with Dr. Sean O'Mara, a former undercover narcotics agent, criminal prosecutor, emergency medicine physician, and retired U.S. Army Colonel who assisted the White House and Senior Executive Service, treating Vice President Dick Cheney, former President Bill Clinton, and Secretary of State Colin Powell. Today he's recognized as the world's most experienced physician in eliminating visceral fat and epicardial adipose tissue (EAT), the inflammatory fat now linked to nearly every major chronic disease and accelerated aging. He founded Influence Medicine, a specialty built around helping senators, heads of state, and top executives optimize their biology so they can perform and lead at the highest level.
Dave and Dr. O'Mara break down the real difference between visceral fat and subcutaneous fat, why a visible six-pack might signal hidden disease, and how MRI scans reveal what your mirror never will. They dig into the biohacking strategies that actually shift your body composition: fasting protocols that build beneficial fat instead of burning it away, microbiome optimization for fat metabolism, and the supplements and functional medicine tools Dr. O'Mara uses with his highest-performing clients. They also cover the gut-hormone connection driving modern metabolic dysfunction, why political leaders are quietly getting scanned, and what your face reveals about your visceral fat levels before you ever step on a scale.
You'll Learn:
The real difference between visceral fat, subcutaneous fat, and why one protects you while the other kills you Why a six-pack might be hiding disease your MRI would catch How a 72-hour fasting protocol can build the good kind of fat through adiponectin signaling What your face reveals about your visceral fat and longevity risk The gut-hormone connection driving testosterone, metabolism, and inflammation Why senators and world leaders are getting scanned for hidden fat How microbiome health, fasting, and functional medicine work together for fat loss and longevityThank you to our sponsors!
- Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com.
- Suppgrade Labs | Get real restorative sleep with Quiet Mode. Use code DAVE15 at shopsuppgradelabs.com.
- Puori | Use code DAVE at puori.com/DAVE to get 32% off your first Puori CP1 Pure Collagen. Order when you start a subscription. You save more than $26
- LMNT | Right now you can get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinkLMNT.com/dave
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: visceral fat vs subcutaneous fat, how to reduce visceral fat, best fat for longevity, MRI body scan benefits, Prenuvo full body scan, what is epicardial fat, skinny fat TOFI explained, why is my six pack unhealthy, 72 hour fasting benefits, fasting and testosterone, how to build subcutaneous fat, biohacking visceral fat, Sean O'Mara doctor, influence medicine, fecal microbiota transplant benefits, gut microbiome and fat loss, Dave Asprey, biohacking, longevity
Resources:
• Learn More About Dr. O’Mara’s Work At: https://drseanomara.com/
• Get $300 Off Your Next Prenuvo MRI Scan: https://prenuvo.com/?discount=Dave
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15?
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:58 – Intro
02:38 – Fat Type Basics
04:19 – Reviewing Dave's Scan
08:04 – Good Fat vs. Bad Fat
16:49 – Fertility & Pregnancy
19:47 – Personality & Health
21:51 – Wealth & Health Neglect
30:32 – Insurance Incentives
39:29 – Microbiome & Disease
40:41 – FDA & Fecal Transplants
42:57 – Viome & Biomarker Data
45:40 – Skinny Fat & Appearance
49:44 – Building Subcutaneous Fat
52:57 – Fasting Protocol
58:37 – Closing
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Most people think biohacking is only for billionaires with access to expensive machines, private clinics, and million-dollar anti-aging protocols. But the truth is, some of the most powerful upgrades in your biology start with the basic signals your body receives every single day.
In this video, Dave Asprey breaks down how to start biohacking with around $200 by focusing on the foundations that control your sleep, energy, focus, and cellular repair. These are the simple changes that can create a massive difference before you ever spend money on advanced technology.
If you’ve ever wanted to feel sharper, recover better, sleep deeper, and support your body’s natural repair systems without wasting money on random gadgets, this video shows you where to start.
Try Danger Creatine: https://dangercoffee.com/products/danger-creatine
Try TrueDark glasses: https://truedark.com
Try Danger Coffee: https://dangercoffee.com/discount/davetube
Try Suppgrade Labs: https://shopsuppgradelabs.com/
I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a waste of money, and the exact stack that delivers hours of clean focus without the afternoon crash.
The shift is simple: focus isn't a willpower problem. It's an energy production problem inside your brain. Once you fuel it at the cellular level, deep focus stops being a struggle and becomes the default state.
Thank you to our sponsors!
ECHO Water | Go to http://echowater.com/daveand use code DAVE10 for 10% off your ECHO Flask.The One Device | Use code DAVE for $10 off at theonedevice.com/daveiRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE00:00 – Trailer
00:53 – Sleep Environment Matters
03:44 – Red Light Bulbs
04:50 – Blackout Curtains
05:16 – Light-Blocking Glasses
07:16 – Morning Supplement Stack
07:41 – Creatine for the Brain
11:48 – MCT Oil Fuel
13:06 – Cellular Cleanup (Autophagy)
15:12 – Magnesium for Sleep
16:56 – Full Stack Recap
18:26 – Biohacking Is Accessibl
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/
TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Shawn Stevenson On The Science of Family Meals, Oxytocin, and Longevity
Your dinner table might be the most overlooked biohack in your house. This episode reveals the exact minimum dose of family meals that lowers a child's risk of obesity, the hormone your body releases every time you eat with people you love, and why teaching your kids to cook may protect their metabolism for life.
Host Dave Asprey sits down with Shawn Stevenson, founder of The Model Health Show and author of the bestselling Eat Smarter Family Cookbook series. Shawn spent over two decades studying nutritional science and functional medicine after recovering from advanced degenerative disc disease at age 20, and he has become one of the most trusted voices in health media for turning peer-reviewed research into real-world family habits.
Shawn and Dave break down the science of community eating, including new research on oxytocin, nervous system regulation, and metabolism that shows why sitting down together beats eating alone every time. They cover the four biological drives running your behavior, the connection between family culture and longevity, and how simple shifts like humming, breathwork, and intentional meals can support brain optimization and anti-aging at a cellular level. This conversation also dives into the five love languages hidden inside food, a bio-photon DNA experiment that reframes how energy moves between people, and the exact number of meals per week that changes a child's health trajectory.
You'll Learn:
The minimum effective dose of family meals per week that lowers childhood obesity and disordered eatingHow oxytocin and a regulated nervous system change what happens at the dinner tableWhy teaching kids to cook protects their metabolism and prevents dependence on ultra-processed foodHow the five love languages show up in how you cook, serve, and share foodThe bio-photon DNA experiment that shows how human energy fields affect the world around youWhy culture is something your family creates, not just something you inheritHow humming and breathwork practices can shift your nervous system and even change your voiceDave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.
Keywords: Shawn Stevenson, Dave Asprey, The Human Upgrade, biohacking, family dinner, family meals, community eating, longevity, functional medicine, oxytocin, nervous system regulation, childhood obesity, teaching kids to cook, five love languages, Model Health Show, Eat Smarter Family Cookbook, brain optimization, anti-aging, metabolism, nutrition science, mental health, family culture, healthy habits, minimum effective dose, human performance
Thank you to our sponsors!
-Gatlan | Book your free consultation at www.gatlan.com/DAVE
-Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time
-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
Resources:
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Why Oral and IV Glutathione Never Actually Reach Your Cells (The Delivery Breakthrough Changing Everything)
Most of the supplements you're taking aren't failing you, they're failing to ever reach the cells that need them, and almost nobody selling them wants you to know that. This episode hands you the delivery breakthrough that actually gets it there.
Use code DAVE for a discount at aurowellness.com/dave
Host Dave Asprey sits down with Dr. Nayan Patel, a pharmacist, researcher, and founder of Auro Wellness, whose work centers on solving one of biohacking's most stubborn problems: getting nutrients past the bloodstream and into the cells that actually need them. He holds 14 patents in delivery technology, partners in the high-end longevity clinic Unlimited Life, and has spent over two decades studying glutathione, the master antioxidant his own research helped bring into modern biohacking.
Dave and Dr. Patel break down a 2011 University of Texas study showing that oral and liposomal glutathione are completely broken down into raw amino acids before absorption, meaning none of it reaches the bloodstream as glutathione, a pattern that holds true even for IV administration. They dig into new brain-imaging research showing topical glutathione crossing into neural tissue within 20 minutes, why senescent "zombie cells" may be directly tied to glutathione shortfalls, and why NAD, despite its reputation as the ultimate longevity molecule, is actually dependent on glutathione to do its job. They also cover the real purity ceiling on GHK-copper peptides, safe upper limits for glycine and NAC before they start working against you, a topical alcohol protocol that clears acetaldehyde without triggering a breathalyzer, and why oxidative stress from GLP-1 use is quietly driving one of the drug class's least-discussed side effects.
You'll Learn:
Why oral, liposomal, and even IV glutathione never actually reach your cells intact, and what a 2011 UT study proved about it How topical glutathione was shown to cross into brain tissue within 20 minutes, and what that means for neurological aging Why senescent "zombie cells" may be directly linked to glutathione shortfalls, and how one longevity clinic reversed markers by 70% in a year Why NAD isn't the "ultimate longevity drug" it's marketed as, and its actual dependent relationship with glutathione The real purity ceiling on GHK-copper peptides, and why 73% is currently the best available anywhere Safe upper limits for glycine and NAC, and the oxalate crystal and Parkinson's-like risks of overdoing either one A topical alcohol protocol that clears acetaldehyde fast enough to beat a breathalyzer Why GLP-1 drugs are quietly driving oxidative stress, and what most patients are missing to counter itThank you to our sponsors!
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
- OneSkin | Get 15% off OneSkin with the code DAVE at https://www.oneskin.co/DAVE #oneskinpod
- Caldera + Lab | A small habit with big results. Go to CalderaLab.com/DAVE and use code DAVE for 20% off your first order.
- Fatty15 is on a mission to support Healthy Aging for All, including all ages and stages of life. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com and using code DAVE at checkout
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: glutathione, Nayan Patel, Ora Wellness, glutathione absorption, transdermal delivery, senescent cells, zombie cells, cellular aging, GHK-copper peptide, NAD, NAD supplements, NAC, glycine, GlyNAC, oxalate crystals, alcohol metabolism, acetaldehyde, GLP-1, semaglutide, oxidative stress, heavy metal detox, mercury toxicity, BPC-157, biohacking, longevity, functional medicine
Resources:
• Get A Discount On Auro Wellness Products - Use code DAVE: aurowellness.com/dave
• Learn More About Dr. Patel’s work at: http://aurowellness.com/dave
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:43 – Episode Intro
03:16 – Glutathione Basics
07:34 – Senescent Cells
11:07 – Cellular Delivery Science
14:20 – GlyNAC Precursors
21:37 – Amino Acid Ratios
25:18 – GHK Copper Peptide
28:41 – Purity & Manufacturing
31:34 – Glutathione vs. NAD
33:49 – Absorption Studies
37:51 – Heavy Metals & Toxins
42:35 – Alcohol & Glutathione
47:43 – Mortality & Reincarnation
49:54 – GLP-1s & Anhedonia
53:25 – Future of Peptides
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Cardiologist Dr. Peter McCullough on mRNA Persistence, Nattokinase, and the Fight Over COVID-19 Treatment"
Six years after standing before the US Senate and calling out the pandemic response in real time, Dr. Peter McCullough returns with new evidence on where the spike protein came from, how long it persists in the body after infection or vaccination, and what's being done to break it down. This episode traces the science from a 2015 gain-of-function paper to a patient still showing circulating spike protein 3.6 years after vaccination.
Get Dr. McCullough's free spike protein guide: myfreespikeguide.com
Host Dave Asprey sits down with Dr. Peter McCullough, a physician trained in internal medicine, cardiology, and epidemiology, and one of the most published and most censored voices of the COVID-19 pandemic. He authored the first multi-drug treatment protocol for COVID-19, testified before the US Senate in 2020 and again in 2025, and has published extensively in the peer-reviewed literature on vaccine safety, spike protein biology, and early treatment. His book Courage to Face COVID-19 and his most recent New York Times bestseller, Vaccines, Mythology, Ideology and Reality, examine the history and science behind vaccine policy.
Dave and Dr. McCullough trace the origins of the spike protein back to 2015 and 2016 research papers describing a lab-created, SARS-like coronavirus explicitly labeled "poised for human emergence," and discuss the funding, institutions, and researchers involved. They break down why synthetic mRNA vaccines resist the body's normal RNA breakdown process, what a patient case revealed about spike protein circulating 3.6 years after vaccination, and how nattokinase, a natural enzyme, has shown the ability to break the spike protein down. They also cover the suppression campaigns against ivermectin and hydroxychloroquine, the wartime propaganda origins of terms like "misinformation" and "anti-vaxxer," and what Dr. McCullough says he would do differently if he ran HHS. The conversation closes with new research on cognitive superagers, the small percentage of people who reach 100 with intact memory and health.
You'll Learn:
Why 2015 and 2016 research papers described a lab-created coronavirus as "poised for human emergence" years before the pandemic Why synthetic mRNA in COVID-19 vaccines resists the body's natural RNA breakdown process What one patient's case revealed about spike protein still circulating 3.6 years after vaccination How nattokinase, a natural enzyme, has been shown to break down the spike protein Why the FDA and FTC targeted ivermectin, hydroxychloroquine, and companies selling nasal sprays during the pandemic The wartime propaganda origins of terms like "misinformation," "disinformation," and "anti-vaxxer" What Dr. McCullough says he would do first if he were running HHS What research on cognitive superagers reveals about the small number of people who reach 100 with intact healthThank you to our sponsors!
- TrueDark | Visit truedark.com and use code DAVEASPREY15 (discount applies to all frames except Aegis)
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- Qualia | Go to qualialife.com/ASPREY for 50% off, and use code ASPREY for an additional 15% off.
- ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: spike protein detox, how long does spike protein last in your body, nattokinase spike protein, mRNA vaccine side effects, is the spike protein still in my blood, gain of function research explained, where did COVID come from, Wuhan lab leak evidence, ivermectin banned, why was hydroxychloroquine banned, vaccine injury compensation act, mRNA vaccine shedding, spike protein detox protocol, how to live to 100, cognitive superagers, Peter McCullough, Dave Asprey
Resources:
• Learn More About Dr. McCullough’s Work At: https://www.twc.health/pages/focal-points
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15?
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:43 – Intro
02:10 – 2020 Public Health Failures
05:07 – Vaccine History & Mythology
07:19 – Vaccine Hesitancy as Disease
13:12 – Masks & Lockdown Absurdity
18:03 – War on Hydroxychloroquine
23:56 – Ivermectin Suppression
28:58 – FTC Misinformation Crackdown
31:18 – Propaganda Terms Explained
39:55 – McCullough's Confidence & Career
43:08 – Spike Protein Origins
57:10 – Nattokinase & Spike Clearance
58:50 – mRNA Persistence in Body
1:11:50 – Fixing the System
1:17:32 – Political Divisiveness
1:22:41 – Secrets to Longevity
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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A Nobel Prize-winning discovery revealed that your body has a built-in repair system that can help clear out old cellular damage and support healthier aging from the inside out.
In this video, Dave Asprey breaks down the strange Japanese breakfast ritual linked to some of the longest-living people on Earth, why modern life can shut down your body’s natural repair mode, and how one specific food may help wake it back up.
You’ll learn how this process supports brain clarity, energy, inflammation, recovery, and biological age, plus how to use it through food, supplements, sleep, exercise, and testing so you can actually track whether your body is responding.
Try Danger Creatine: https://dangercoffee.com/products/danger-creatine
Try TrueDark glasses: https://truedark.com
Try Danger Coffee: https://dangercoffee.com/discount/davetube
Try Suppgrade Labs: https://shopsuppgradelabs.com/
I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a waste of money, and the exact stack that delivers hours of clean focus without the afternoon crash.
The shift is simple: focus isn't a willpower problem. It's an energy production problem inside your brain. Once you fuel it at the cellular level, deep focus stops being a struggle and becomes the default state.
Thank you to our sponsors!
Gatlan | Book your free consultation at www.gatlan.com/DAVEThe One Device | Use code DAVE for $10 off at theonedevice.com/daveiRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:
0:00 – Japanese Breakfast Secret
1:02 – Damage vs. Repair
3:39 – What Is Autophagy?
6:03 – Natto & Longevity
7:34 – Using Spermidine Correctly
9:38 – The Under-Dosing Mistake
11:01 – Stacking Habits
12:21 – Measuring Biological Age
12:59 – Take Control of Your Biology
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/
TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Nervous System Hacking, Willpower vs Habit Systems, Calendar Time Blocking, and the Wallet Posture Fix Damaging Your Spine
Most people think surviving a life-threatening situation comes down to luck. Jordan Harbinger did it twice, and what got him out wasn't luck, it was a nervous system he had trained to override panic. This episode breaks down what actually happens in your body during a real fight-or-flight response, and how those same tools power his approach to human performance and hacking the excuses that keep most people stuck.
Host Dave Asprey sits down with Jordan Harbinger, founder of The Art of Charm, one of the top podcasts in the world on charisma, negotiation, and relationship building. Jordan built his expertise the hard way, surviving two real kidnapping attempts using the same psychological principles he now teaches to entrepreneurs and high performers. That firsthand experience under extreme pressure is exactly what makes his insight into stress, willpower, and behavior change worth trusting.
Jordan and Dave dig into what your nervous system does under real threat, why adrenaline hijacks rational thought, and how to build resilience that holds up when it matters most. They unpack why willpower fails as a long-term strategy, and why building smarter systems, not more discipline, is the real key to lasting change. Jordan breaks down his calendar-based productivity method, explains how sleep optimization and chronotype shape daily performance, and reveals a bizarre, physical habit quietly wrecking most people's spine and posture without them realizing it.
This is essential listening for anyone serious about biohacking, human performance, hacking the nervous system, brain optimization, neuroplasticity, and longevity, and building resilience that performs under real pressure, not just in theory.
You'll Learn:
How Jordan Harbinger used psychology to talk his way out of two real kidnapping attempts What actually happens in your nervous system during a fight-or-flight response Why willpower fails as a long-term strategy and what to build instead How a calendar-based system eliminates decision fatigue and boosts daily performance How sleep optimization and chronotype affect brain function and productivity Why your wallet might be quietly damaging your spine and posture How to rewire ingrained habits and reactions through neuroplasticity and awarenessThank you to our sponsors!
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
- EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.
- iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: fight-or-flight response, nervous system regulation, adrenaline and cortisol, stress physiology, psychological resilience, kidnapping survival, Jordan Harbinger, The Art of Charm, willpower vs systems, habit change, decision fatigue, calendar time blocking, productivity systems, chronotype, sleep optimization, posture and spine health, nervous system hacking, neuroplasticity, self-deception and excuses, high performance psychology, biohacking, human performance
Resources:
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15?
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:58 – Guest Introduction
02:33 – First Kidnapping Story
06:54 – Second Kidnapping Story
14:25 – Escape & Evasion Training
23:26 – New Year's Resolutions
38:30 – Calendar Productivity System
51:45 – Wallet Audits & Minimalism
55:23 – Talking Your Way Out of Tickets
1:00:42 – Final Advice: Relationships
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Neurologist Dr. David Perlmutter Explains Brain Inflammation and Alzheimer's Risk
Your brain has its own immune system, and when it turns against you, it becomes the hidden driver behind Alzheimer's, Parkinson's, depression, and even long COVID. This episode hands you the science to recognize it early and reverse it.
Get Dr. Perlmutter’s new book Brain Defenders: https://drperlmutter.com/books/brain-defenders/
Host Dave Asprey sits down with Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work sits at the intersection of neurology, nutrition, and brain health. He is a Fellow of the American College of Nutrition, serves on its Board of Directors, and sits on the Editorial Board of the Journal of Alzheimer's Disease. His books, including the number one bestseller Grain Brain, span 32 languages and have sold over a million copies, and his upcoming release, Brain Defenders, explores the pivotal role of microglia, the brain's immune cells, in protecting, repairing, and reprogramming the brain for lifelong resilience.
Dave and Dr. Perlmutter break down how microglia, the brain's resident immune cells, shift from a supportive state into a destructive one called M1, and why this shift, not amyloid plaque, may be the real driver of Alzheimer's, Parkinson's, and other neurodegenerative conditions. They dig into why the leading amyloid-clearing drugs fail to improve cognition, what a landmark JAMA study revealed about reversing cognitive decline through lifestyle intervention alone, and why a single daily serving of ultra-processed food raised Alzheimer's risk by 13 percent in a 12.7 year study. They also cover new research on GLP-1 drugs and brain inflammation, the surprising role of gum disease and oral bacteria in dementia risk, and why 40 hertz light therapy is emerging as a low-cost tool for clearing brain plaque and calming neuroinflammation.
You'll Learn:
Why the shift from supportive to destructive brain immune cells may be the true root cause of Alzheimer's and Parkinson's Why leading Alzheimer's drugs fail to improve cognition, and what the original research behind the amyloid hypothesis actually showed How one daily serving of ultra-processed food raises Alzheimer's risk, and what a landmark lifestyle intervention study found instead Whether GLP-1 drugs help or harm brain inflammation, based on new Parkinson's and Alzheimer's trial data How gum disease and oral bacteria are linked to dementia, and simple daily habits that reduce that risk Why 40 hertz light therapy is emerging as a tool to clear brain plaque and calm neuroinflammation How ketones, DHA, and metabolic health protect the brain after head injuryThank you to our sponsors!
- Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com.
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- Pique | Head over to Piquelife.com/Dave to get 20% off your order. That's P-I-Q-U-E life dot com slash DAVE
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: microglia, brain inflammation, Alzheimer's prevention, Parkinson's disease, amyloid hypothesis, neurodegeneration, GLP-1 drugs, semaglutide, ultra-processed food, gum disease and dementia, oral microbiome, 40 hertz light therapy, ketones, DHA, mitochondria, brain fog, long COVID, David Perlmutter, Brain Defenders, Grain Brain, functional medicine, biohacking, longevity, neuroplasticity
Resources:
• Get Dr. Perlmutter’s New Book Brain Defenders: https://drperlmutter.com/books/brain-defenders/
• Learn More About Dr. Perlmutter’s Work At: https://drperlmutter.com/
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15?
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:40 – Intro
02:38 – Ultra-Processed Foods
06:34 – Are Carbs Bad?
08:48 – Alcohol & Brain Health
12:28 – Microglia & Inflammation
24:37 – Head Injury & Recovery
29:27 – Oral Bacteria & Dementia
34:08 – GLP-1s & Brain Inflammation
40:20 – 40 Hertz Light Therapy
48:35 – Air Pollution vs. Lead
50:27 – David's Closing Truth
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Near-Infrared Light Therapy & EMF Shielding with SaunaSpace Founder Brian Richards
Your mitochondria are starving for a nutrient you've probably never tracked, and it's not a vitamin or a macro. This episode reveals how a forgotten 1910 therapy uses light to physically restructure water inside your cells, unlocking a mechanism for healing, detox, and mitochondria repair that most of biohacking has completely overlooked.
Go to https://sauna.space/ and use code ‘Dave’ for a 15% discount!
Host Dave Asprey sits down with Brian Richards, founder of SaunaSpace and a leading voice in incandescent light therapy and infrared sauna engineering. With a background in chemistry and organic synthesis, Brian spent over a decade building a science-backed alternative to LED-based light therapy rooted in full-spectrum incandescent light and deep radiant heat. After healing his own insomnia, adrenal fatigue, and brain fog through light and heat exposure, he developed the FireLight Spectrum, a technology engineered to restore what modern lighting strips away.
Dave and Brian trace incandescent light therapy back to Dr. John Harvey Kellogg's 1910 book on light therapeutics, and explain why the same institutional forces that suppressed chiropractic care and natural medicine buried this practice for over a century. They break down how near-infrared light penetrates the body to charge water into a more bioavailable state, boost glutathione and melatonin production, and repolarize cellular voltage for better metabolism and longevity. The conversation also covers why blue light from LEDs devastates hormones, testosterone, and fertility, how EMF exposure silently drains human performance, and why grounding and Faraday shielding matter more than most supplements on the market.
You'll Learn:
Why near-infrared light functions as an essential nutrient your body cannot make without it How light physically restructures water to improve mitochondria function and cellular energy The suppressed history of Dr. Kellogg's incandescent light therapy and why it disappeared How blue light exposure crashes testosterone and disrupts fertility and hormone regulation Why EMF shielding and grounding are critical, overlooked tools for longevity and recovery How to use infrared light like a daily supplement instead of an occasional treatment Why carnivore-adjacent, nutrient-dense eating pairs naturally with light and heat therapyThank you to our sponsors!
- ELITE Performance Coaching | If you’d like to discover where you may be addicted to struggle, allergic to success, and what may be standing between you and your next breakthrough, visit FastestChange.com
- Longevity Farms | Go to getlongevityfarms.shop. Use code DAVE for 20% off your next order.
- Calroy | Go to calroy.com/dave for the clinical research, your discount, and a 45-day money-back guarantee.
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Brian Richards, SaunaSpace, incandescent light therapy, near-infrared light, FireLight Spectrum, Dr. John Harvey Kellogg, Light Therapeutics, exclusion zone water, Gerald Pollack, EMF shielding, Faraday cage, grounding mat, earthing, redox potential, mitochondrial energy, glutathione, melatonin, blue light toxicity, circadian biology, red light therapy, heat shock proteins, vitamin D, sun callus, Danger Coffee, Flexner Report, testosterone, biophotons
Resources:
• Go to https://sauna.space/ and use code ‘Dave’ for a 15% discount!
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15?
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:46 – Meet Brian Richards
03:17 – Kellogg's Light Bath History
09:04 – Persecuted Light Pioneers
12:47 – Near-Infrared Science
16:07 – Blue Light Damage
19:26 – Sunscreen Myths
23:52 – Antidote & Melatonin
33:24 – Exclusion Zone Water
37:52 – Heart as a Vortex
41:47 – Fireplace & Infrared Deficiency
46:15 – FireLight Bulb Design
51:52 – EMF Shielding
55:16 – Faraday Cage & Grounding
1:05:51 – Sauna.Space Discount
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
-
Try Danger Creatine: https://dangercoffee.com/products/danger-creatine
Try TrueDark glasses: https://truedark.com
Try Danger Coffee: https://dangercoffee.com/
Try Suppgrade Labs: https://shopsuppgradelabs.com/
I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a waste of money, and the exact stack that delivers hours of clean focus without the afternoon crash.
The shift is simple: focus isn't a willpower problem. It's an energy production problem inside your brain. Once you fuel it at the cellular level, deep focus stops being a struggle and becomes the default state.
Thank you to our sponsors!
ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:
0:00 – The Longevity Switch
0:47 – Why Mitochondria Matter
2:28 – What Mitophagy Is
2:46 – How Mitophagy Works
4:18 – What Shuts It Off
8:54 – The Damage Compounds
9:22 – How to Turn It Back On
10:31 – Signal 1: Fasting
11:48 – Signal 2: Exercise (REHIT)
12:30 – Signal 3: Cold Exposure
13:22 – Signal 4: NAD+
14:29 – Signal 5: Urolithin A and Spermidine
Connect with Dave Asprey!
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Upgrade Labs: https://upgradelabs.com
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See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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GLP-1 Side Effects, Gut Microbiome & Brain Health, Toxoplasmosis Risks, and the Dirty Dozen Explained
Plasma Acetate Emerges As Key Gut-Brain Messenger In Older Adults
A study published in Nature Communications examined how gut bacteria relate to plasma acetic acid, a short-chain fatty acid produced when gut microbes ferment fiber, and found that higher acetate levels tracked with lower triglycerides, higher HDL cholesterol, lower body fat, larger thalamic brain volume, and stronger performance on judgment-related cognitive tasks. Mediation analysis showed acetate acts as a direct link between specific gut bacteria, including Oscillibacter and Coprococcus, and these health outcomes. Host Dave Asprey breaks down why this elevates fiber fermentation, not fermented beverages, as the real lever for gut-brain health, and separates the evidence-backed mechanism from the kombucha-as-shortcut assumption.
Source:
https://www.nature.com/articles/s43856-026-01566-x
~~
GLP-1 Drugs Linked To Sharp Rise In Smell And Taste Disturbances
A JAMA Otolaryngology cohort study tracking over 438,000 GLP-1 users against matched controls found a 48% higher risk of new smell or taste disturbances over two years, with smell disturbances up 81% and taste disturbances up 52%. Diagnoses included anosmia, parosmia, and parageusia, with researchers pointing to GLP-1 receptor activity in the olfactory bulb and other chemosensory pathways as a possible mechanism. Host Dave Asprey unpacks why this signal got buried under muscle loss and gut motility headlines, and what it means for anyone currently on or considering GLP-1 therapy.
Sources:
https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2850571
https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2026.1498
https://trial.medpath.com/news/glp-1-receptor-agonists-linked-to-increased-risk-of-smell-and-taste-disturbances-study-finds
~~
Scientists Push For Toxoplasmosis To Be Recognized As A Neglected Tropical Disease
A viewpoint paper in PLOS Neglected Tropical Diseases argues that toxoplasmosis, a parasitic infection carried by roughly one in three people globally, deserves WHO neglected tropical disease status given its outsized impact on vision and maternal-child health. Ocular toxoplasmosis is the most common intra-ocular infection worldwide, and an estimated 190,000 babies are born with congenital toxoplasmosis each year, concentrated in low-resource regions. Despite the scale, there is still no vaccine and no standard global treatment protocol. Host Dave Asprey explains why common, quiet health threats get chronically underfunded compared to dramatic outbreaks, and what pregnant listeners specifically should know about exposure risk.
Source:
https://www.sciencealert.com/parasite-affecting-1-in-3-people-is-a-serious-risk-to-human-health-scientists-warn
~~
Yale-Oxford Data Shows Exercise May Boost Mental Health More Than A Raise
An analysis of CDC survey data from over 1.2 million U.S. adults found that people who exercise regularly report 1.5 to 2 fewer poor mental health days per month than non-exercisers, a benefit comparable to earning about $25,000 more per year. The data also revealed an inverted-U relationship, with optimal benefits at three to five sessions a week and diminishing or reversed returns at extreme volumes. Host Dave Asprey breaks down why moderate, consistent movement outperforms income as a mental health lever, and why overtraining carries its own psychological cost.
Sources:
https://www.weforum.org/stories/2019/04/exercise-officially-makes-you-happier-than-money-according-to-yale-and-oxford-research/
https://medicine.yale.edu/news-article/exercise-linked-to-improved-mental-health-but-more-may-not-always-be-better/
~~
Unilever Reportedly Exploring $4 Billion Bid For Supplement Brand Thorne
Unilever is said to be evaluating a bid for Thorne, the clinical-grade supplement brand currently owned by private equity firm L Catterton, in a deal that could value the company at up to $4 billion, with Haleon also reportedly circling. The move reflects a broader trend of major consumer-health conglomerates acquiring practitioner-trusted, lab-forward wellness brands. Host Dave Asprey weighs in on what happens to product quality and innovation when founder-led, science-first supplement companies get absorbed into shareholder-first parent corporations.
Source:
https://www.reuters.com/business/unilever-explores-bid-supplements-maker-thorne-ft-reports-2026-06-26/
~~
New Research Maps How Your Microbiome Processes Plant Compounds, And What It Means For Your Produce Aisle Choices
Researchers mapped 775 phytonutrients from over 1,100 edible plants against nearly 2,000 gut bacterial enzymes across thousands of human microbiomes, linking that enzyme activity to outcomes in IBD, colorectal cancer, and fatty liver disease. Individuals varied widely in how many of these compounds their gut could actually process, and in mouse studies, strawberries reduced colitis activity only in mice with an intact microbiome. Host Dave Asprey explains why the plant itself isn't the active ingredient, your bacteria are, and connects the findings to this year's Environmental Working Group Dirty Dozen and Clean Fifteen lists to help listeners decide where organic actually matters.
Sources:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12768975/
https://www.eurekalert.org/news-releases/1108351
https://www.nature.com/articles/s41564-025-02197-z
~~
This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insights into the gut-brain axis, an underreported GLP-1 side effect, a global parasite hiding in plain sight, the real ROI of exercise on mental health, consolidation in the supplement industry, and how your microbiome determines what your produce actually does for you. Host Dave Asprey connects clinical research, large cohort studies, mechanistic biology, and industry news into practical frameworks for improving gut health, brain performance, and long-term resilience.
New episodes every Tuesday, Thursday, Friday, and Sunday.
Keywords: plasma acetate gut brain axis, short chain fatty acids, gut microbiome cognition, GLP-1 smell taste disturbances, anosmia parosmia GLP-1, semaglutide side effects, toxoplasmosis neglected tropical disease, Toxoplasma gondii health risks, congenital toxoplasmosis, exercise mental health study, exercise versus income happiness, overtraining mental health, Unilever Thorne acquisition, supplement industry consolidation, phytonutrient gut bacteria enzymes, polyphenol metabolism microbiome, Dirty Dozen Clean Fifteen 2026, pesticide residue produce, biohacking news 2026, Dave Asprey, The Human Upgrade
Thank you to our sponsors!
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
- Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.
- iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
Resources:
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Story #1: Acetate & Gut-Brain Health
01:57 – Story #2: GLP-1s & Smell/Taste Loss
03:22 – Story #3: Toxoplasmosis Risks
04:33 – Story #4: Exercise vs Income
05:53 – Story #5: Phytonutrients & Gut Enzymes
07:45 – Dirty Dozen & Clean Fifteen
08:46 – Story #6: Thorne Acquisition
09:49 – Takeaway
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Carnivore Diet, Cholesterol, Gut Bacteria, Microbiome, and Fasting Insulin Results from a 90-Day Self-Experiment
What if cutting out fiber entirely actually improved your gut bacteria? This episode breaks down a real 90-day carnivore self-experiment, complete with before and after blood work, stool testing, and continuous glucose data, that challenges everything you think you know about fiber, cholesterol, and metabolic health.
Watch this episode on YouTube for the full video experience:
https://www.youtube.com/@DaveAspreyBPR
Host Dave Asprey sits down with Ben Azadi, founder of Keto Kamp and bestselling author of Metabolic Freedom. After overcoming obesity and severe health challenges, Ben has spent years educating millions of people on metabolic health, fasting, ketosis, and biohacking strategies through his podcast, books, and YouTube channel with over a million subscribers. He is known for turning complex science into practical tools anyone can use to burn fat, boost human performance, and support long-term longevity.
Ben walks through what happened when he ate nothing but meat, eggs, and dairy for 90 straight days, tracking everything from his microbiome diversity to his LDL particle size. His cholesterol numbers spiked, but the full lipid panel tells a very different story than most doctors would assume. They get into why ketosis works better when you cycle in and out of it, how sodium and electrolytes play a bigger role in insulin resistance than most people realize, and why eating 17 to 23 times a day might be quietly wrecking your metabolism.
The conversation also covers the real science behind creatine absorption, why Dave adds his to hot coffee for better brain uptake, the truth about cooking oils and smoke points, and why cold plunging is one of the most misunderstood biohacks in the wellness space. Dave and Ben dig into mitochondria, fasting protocols, sleep optimization, and the supplements that actually move the needle for energy, fat loss, and anti-aging.
This is essential listening for anyone serious about biohacking, functional medicine, brain optimization, and building a body that performs at a higher level for longer.
You'll Learn:
What 90 days of zero fiber actually did to his gut bacteria and microbiome diversity Why his cholesterol went up but his cardiovascular risk markers stayed low The real reason cyclical ketosis works better than staying in ketosis full time How sodium and electrolyte intake affects insulin resistance and metabolism Why eating too frequently keeps your body stuck in glucose and insulin spikes The creatine hack that increases brain absorption using hot coffee Why cold plunging is overrated for most people who skip the hormesis basicsThank you to our sponsors!
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time.
- ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Ben Azadi, Keto Kamp, carnivore diet, 90-day carnivore experiment, gut microbiome, gut bacteria diversity, fiber-free diet, LDL particle size, cyclical ketosis, fasting, autophagy, electrolytes, sodium intake, insulin resistance, fasting insulin, creatine, blood-brain barrier, melatonin, mitochondria, hormesis, cold plunge, dopamine receptors, olive oil polyphenols, smoke point, beef tallow, seed oils, HRV, sleep optimization, KetoFlex, Metabolic Freedom
Resources:
• See All Of Ben Azadi's Content At: https://benazadi.com/
• Check Out Ben’s YouTube Channel: https://www.youtube.com/@KetoKamp
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
01:15 – 90-Day Carnivore Experiment
04:43 – Cholesterol & Lipid Results
09:12 – Cyclical Keto Approach
20:19 – Reading Body Signals
26:36 – Danger Creatine Launch
31:55 – Calories vs. Hormones
33:53 – Root Cause of Insulin Resistance
35:37 – Sodium & Electrolytes
45:11 – Sleep Optimization
49:19 – Cold Plunging Overrated
51:17 – BICEP & Dopamine Reset
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Your Hormones Are Killing You: Oxytocin, FSH, and the Anti-Aging Protocol Most Doctors Ignore
Your hormones are running your love life, your intuition, your longevity, and your brain, and most doctors are getting it completely wrong. Host Dave Asprey sits down with triple board-certified OBGYN Dr. Anna Cabeca to break down the clinical science of oxytocin, female pleasure, hormonal optimization, and why fixing your hormones can make your 70s the best decade of your marriage.
Dr. Anna Cabeca is a triple board-certified OBGYN and fellow of gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine, with additional board certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. She is the bestselling author of The Hormone Fix, Keto-Green 16, and MenuPause, and has spent decades researching the clinical intersection of oxytocin, cortisol, estrogen, and progesterone on women's hormonal health, metabolism, and longevity. Her work on keto-green nutrition, vaginal and bladder microbiome health, and bioidentical hormone replacement has made her one of the most credentialed and clinically experienced voices in women's functional medicine practicing today.
Dave and Dr. Anna break down the real pharmacology of oxytocin, including its role in muscle regeneration, cortisol suppression, mitochondrial signaling, and vagal tone optimization. They expose the toxic ingredients hiding in mainstream lubricants and vaginal hormone creams, including aspartame, parabens, and petroleum derivatives, and explain why the vaginal microbiome is a frontline organ for women's metabolism and anti-aging. They get into the neuroscience of orgasm, pineal gland activation, endogenous DMT release, and the neurochemical cascade behind peak altered states. Dr. Anna also breaks down the Women's Health Initiative disaster, the FDA's recent reversal on bioidentical hormone replacement, and why FSH is a critical and widely overlooked longevity biomarker. High post-menopausal FSH drives neuroinflammation, accelerates bone loss, and degrades brain optimization outcomes, and most physicians are not testing for it.
This is essential listening for anyone serious about biohacking, longevity, anti-aging, functional medicine, human performance, brain optimization, and taking full ownership of their biology.
You'll Learn:
Why oxytocin functions as a regenerative hormone that rebuilds muscle, suppresses cortisol, and supports mitochondria signaling What toxic chemicals are hiding in standard lubricants and vaginal hormone creams and what to use instead How orgasm activates the pineal gland and triggers endogenous DMT release and altered neurological states Why female intuition may be directly linked to mitochondrial density concentrated in the ovaries How elevated FSH drives neuroinflammation, bone loss, and accelerated brain aging in post-menopausal women Why the FDA reversed 30 years of flawed guidance on bioidentical hormone replacement therapy How four days of sensory deprivation supercharges melatonin, oxytocin, and endogenous DMT production Why oxytocin combined with ketamine is being used clinically to break trauma patterns and rewire neural pathways How polyphenols, CoQ10, carnitine, and vagal tone training protect cardiovascular health and support longevity Why polypharma accelerates decline and what functional medicine does differentlyThank you to our sponsors!
- KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off
- Gatlan | Book your free consultation at www.gatlan.com/DAVE
- Redmond Real - Leaf Toothpaste | Go to https://redmond.com/asprey and use code ASPREY for 15% off your first order.
- Neuronic | Go to www.neuronic.online Code DAVE for $100 off
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Dr. Anna Cabeca, The Girlfriend Doctor, oxytocin, bioidentical hormone replacement, FSH, follicle-stimulating hormone, vaginal microbiome, Velve lubricant, Julva, Mighty Maca, cortisol suppression, pineal gland, DMT, neuroinflammation, broken heart syndrome, NT-proBNP, vagal tone, dark retreat, orgasmic meditation, Women's Health Initiative, perimenopause, postmenopause, yoni massage, oxytocin nasal spray, cabergoline, prolactin, Pitocin, CoQ10, carnitine, Arterosil, polypharma, keto-green, The Hormone Fix
Resources:
• Get An Exclusive Offer On Dr. Anna’s Products At: dranna.com/tribe
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
01:37 – What Is Oxytocin?
07:38 – Clean Lube Launch
09:11 – Toxic Lube Ingredients
17:08 – Oxytocin Prescribing
18:58 – FDA Reverses HRT Warning
26:50 – Dark Retreat & DMT
32:15 – Orgasmic Meditation
42:06 – Female Intuition
46:21 – Broken Heart Syndrome
51:15 – FSH & Hormone Monitoring
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
-
You already know something has changed - the energy crashes, the slow recovery, the brain fog that wasn't there ten years ago. Most people assume that's just aging. But it’s NOT. Nobel Prize-winning research has identified a single molecule that controls how fast your body breaks down, and more importantly, exactly why yours is being destroyed faster than it's being rebuilt. The fix isn't complicated, but the order you do it in matters. In this video, Dave breaks down what this molecule is, why your body is actively working against it, and the exact protocol (diet, fasting, exercise, and supplementation) to restore it before the gap gets any wider.
Thank you to our sponsors!
Gatlan | Book your free consultation at www.gatlan.com/DAVEViome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:
0:00 – The Longevity Switch
0:47 – Why Mitochondria Matter
2:28 – What Mitophagy Is
2:46 – How Mitophagy Works
4:18 – What Shuts It Off
8:54 – The Damage Compounds
9:22 – How to Turn It Back On
10:31 – Signal 1: Fasting
11:48 – Signal 2: Exercise (REHIT)
12:30 – Signal 3: Cold Exposure
13:22 – Signal 4: NAD+
14:29 – Signal 5: Urolithin A and Spermidine
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
-
Fish Oil Supplements And Alzheimer’s-Related Decline
A two-year randomized, double-blind, placebo-controlled trial led by researchers at USC tested whether 2,000 mg of DHA fish oil daily could slow Alzheimer’s-related brain changes in 365 adults ages 55–80 who rarely consumed fish and had at least one Alzheimer’s risk factor. Researchers confirmed the supplement reached the brain by measuring a roughly 17% increase in cerebrospinal fluid DHA after six months. Despite successfully increasing brain DHA levels, participants taking fish oil showed no significant improvements in memory, global cognitive function, or hippocampal volume compared to placebo after two years. Host Dave Asprey explains why raising a single biomarker doesn’t always translate into better brain performance, why nutrition works differently inside a complete dietary pattern than as an isolated supplement, and what this study means for anyone relying on fish oil as an Alzheimer’s prevention strategy.
Sources:
https://medicalxpress.com/news/2026-06-fish-oil-supplements-alzheimer-decline.pdf
https://www.cnn.com/2026/06/18/health/omega-3-fish-oil-algae-supplement-wellness
~~
DASH Diet Showed the Strongest Link to Long-Term Brain Health
Researchers from Harvard analyzed dietary data from 159,347 participants across three long-running U.S. health studies to examine how eating patterns influence cognitive aging. Participants completed dietary questionnaires every four years over several decades, allowing investigators to compare six healthy dietary patterns, including the DASH and Mediterranean diets. While all six were associated with better cognitive health later in life, adherence to the DASH diet produced the strongest association, with participants showing roughly a 40% lower risk of subjective cognitive decline and stronger performance on objective cognitive testing. The protective relationship was strongest when healthy eating habits began during midlife. Host Dave Asprey breaks down why blood sugar control, lower inflammation, and healthier blood vessels may be the real drivers behind long-term brain resilience, and why your dietary choices in your 40s and 50s may have an outsized impact on cognitive aging decades later.
Sources:
https://jamanetwork.com/journals/jamaneurology/article-abstract/2845466
https://www.health.harvard.edu/diet-and-nutrition/harvard-study-six-healthy-diets-linked-with-better-long-term-brain-health
https://www.eurekalert.org/news-releases/1117225
~~
Scientists Identified an Ancient Brain Circuit That Filters Distractions
Johns Hopkins researchers discovered a small population of inhibitory neurons within an evolutionarily ancient brainstem region that appears to control selective attention by determining which sensory information deserves focus and which distractions should be ignored. Mice trained on visual attention tasks consistently ignored irrelevant stimuli until researchers temporarily silenced these neurons, causing even weak distractions to hijack their attention while leaving vision and movement otherwise unaffected. Similar brain circuits exist in birds, reptiles, and other vertebrates, suggesting this attentional filtering system evolved long before the modern human cortex. Host Dave Asprey explains why attention may depend on much older brain circuitry than previously believed, how this discovery could reshape our understanding of ADHD and autism, and why future therapies may target the brainstem instead of the prefrontal cortex.
Sources:
https://www.sciencedaily.com/releases/2026/06/260624025426.htm
~~
Nearly Half of Older Adults Improved With Age Instead of Declining
A Yale-led study followed 11,340 adults age 65 and older for up to 12 years using repeated measurements of cognition and walking speed to better understand how aging changes over time. Rather than finding universal decline, researchers discovered that 45% of participants improved in either cognitive function, physical performance, or both. Nearly one-third experienced measurable cognitive improvements, while over one-quarter improved physically. Researchers also found that participants with more positive beliefs about aging were significantly more likely to improve, even after accounting for education, chronic illness, depression, and other health factors. Host Dave Asprey explores why expectations about aging may become biologically embedded, why decline is far less inevitable than conventional medicine often assumes, and how mindset may directly influence healthy longevity.
Sources:
https://www.sciencedaily.com/releases/2026/06/260620100428.htm
~~
Glyphosate May Be Contributing to Antibiotic-Resistant Superbugs
Researchers publishing in Frontiers in Microbiology examined 102 bacterial strains collected from hospitals, agricultural land, and protected wetlands to investigate whether glyphosate exposure contributes to multidrug antibiotic resistance. Hospital bacteria demonstrated extensive resistance to both antibiotics and glyphosate, while even bacteria living inside protected nature reserves displayed measurable glyphosate resistance despite no direct herbicide application. Genetic analysis suggested resistant bacterial strains may move between agricultural environments and hospitals through shared waterways and sediments. The researchers argue pesticide safety testing should also evaluate whether chemicals encourage antibiotic resistance, one of the world’s fastest-growing public health threats. Host Dave Asprey explains why environmental toxins may have unintended effects on the human microbiome, how herbicides could influence antimicrobial resistance beyond farming, and why environmental biology increasingly belongs in conversations about human health.
Sources:
https://www.sciencedaily.com/releases/2026/06/260620100434.htm
https://www.openaccessgovernment.org/common-weedkiller-glyphosate-linked-to-rise-in-superbugs-scientists-warn/207515/
~~
Butterflies That Barely Age Could Unlock New Longevity Pathways
Researchers from the University of Bristol found that Heliconius butterflies live dramatically longer than closely related butterfly species while aging much more slowly. In one comparison, Heliconius hewitsoni survived up to 348 days, while a closely related species lived only 14 days. Unlike most butterflies, Heliconius feed on pollen throughout adulthood, providing amino acids that help preserve muscle function and physical performance with age. However, even when pollen was removed, these butterflies still significantly outlived their relatives, suggesting evolved genetic and metabolic mechanisms also contribute to their exceptional longevity. Host Dave Asprey explores why nature continues to provide unexpected models for slowing biological aging, what scientists hope to learn from species that naturally maintain function over time, and how comparative biology may uncover entirely new pathways for extending human healthspan.
Sources:
https://www.sciencedaily.com/releases/2026/06/260622014302.htm
~~
This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insights into omega-3 supplementation and Alzheimer’s prevention, nutrition strategies for preserving cognitive health, newly discovered brain circuits controlling attention, the surprising biology behind healthy aging, environmental drivers of antibiotic resistance, and what one remarkably long-lived butterfly can teach us about extending healthspan. Host Dave Asprey connects randomized clinical trials, large population studies, neuroscience discoveries, microbiology research, and evolutionary biology into practical frameworks for improving brain performance, resilience, and longevity.
New episodes every Tuesday, Thursday, Friday, and Sunday.
Keywords: fish oil Alzheimer’s study, DHA supplements memory, omega-3 brain health, DASH diet cognition, dementia prevention diet, cognitive decline nutrition, selective attention brainstem, focus neuroscience, ADHD brain research, positive aging beliefs, healthy aging study, cognitive improvement older adults, glyphosate antibiotic resistance, superbugs glyphosate, environmental toxins microbiome, butterfly longevity research, Heliconius aging, longevity science, biohacking news 2026, Dave Asprey, The Human Upgrade
Thank you to our sponsors!
- Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today
- Neuronic | Go to www.neuronic.online Code DAVE for $100 off
- iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
Resources:
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Intro
00:18 – Story #1 Fish Oil
02:31 – Story #2 DASH Diet
03:49 – Story #3 Brain Stem Attention Filter
05:59 – Story #4 Cognitive Decline Lies
08:24 – Story #5 Glyphosate
10:16 – Story #6 Butterfly Lifespan Research
12:16 – Biohacking Criticism Response
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Most energy drinks trade your long-term health for a short-term jolt. This episode breaks down a smarter approach to energy, one that builds mitochondria function, supports gut health, stabilizes mood, and helps you sleep better at night, all without the crash
-Get 15% off your next order at: https://getmte.com/dave
Host Dave Asprey sits down with Jeff Boyd, founder and chairman of MTE (More Than Energy), the caffeine-free energy drink built around adaptogens, nootropics, and prebiotics that delivers what Boyd calls "energy that loves you back." Before launching MTE, Jeff spent 15 years as President and co-owner of Luggage Free, scaling the company to operations in over 100 countries before selling it in 2019. He brings the operational discipline of a veteran entrepreneur and the personal conviction of someone who built the energy product he actually wanted to exist.
Dave and Jeff get into the full science and strategy behind MTE's ingredient stack, including paraxanthine, ashwagandha, eleuthero, maca, GABA, theanine, and saffron, and why each one was chosen for its role in stress response, brain optimization, and sleep optimization. They also dig into the formulation challenges of building a clean-label supplement over a stimulant base, the real difference between caffeine and its downstream metabolite paraxanthine, and why this blend functions more like a foundational biohacking protocol than a beverage.
You'll Learn:
Why conventional energy drinks wreck your cortisol curve and what to do instead How paraxanthine delivers the benefits of caffeine without the jitters or sleep disruption The adaptogen trio (ashwagandha, eleuthero, and maca) and how they work together for stress response and human performance Why saffron is one of the most underrated nootropics for mood and brain optimization How gut health and the microbiome connect directly to your energy, metabolism, and longevity The mitochondria connection between willpower, physical performance, and entrepreneurial output How AI is reshaping small teams and what founders need to do right now to stay competitive Why the cleanest path to anti-aging and longevity starts with how you manage your energy across the dayThank you to our sponsors!
- Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com.
- Gatlan | Book your free consultation at www.gatlan.com/DAVE
- BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle.
- Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Jeff Boyd, MTE, More Than Energy, caffeine-free energy, paraxanthine, adaptogens, ashwagandha, eleuthero, maca, nootropics, saffron, GABA, theanine, prebiotics, gut health, stress response, cortisol management, sleep optimization, huckleberry acai, clean label formulation, stevia Reb A, energy drink alternative, paraxanthine vs caffeine, afternoon energy, Luggage Free, cycling endurance, long jump training, ADHD entrepreneurship, AI small teams, willpower mitochondria
Resources:
• Get 15% off your next order at: https://getmte.com/dave
• Purchase Dr. Fotuhi’s New Book The Invincible Brain: https://a.co/d/0iHCgPpL
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:42 – What Is MTE?
03:50 – Ingredients Deep Dive
09:49 – Flavors & Formulation
12:31 – Dave's Caffeine Origin
18:35 – Athletic Identity
22:38 – ADHD & Entrepreneurship
26:43 – AI & Future of Work
30:47 – Willpower & Mitochondria
35:34 – MTE Wrap-Up
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Longevity, Trauma Recovery, Circadian Health, Ramadan Fasting & Biohacking
Your nervous system may be aging you faster than your diet. Learn how childhood programming, stress, sleep, fasting, resilience, and environment shape longevity, healthspan, metabolism, and human performance, and discover why some of the most powerful upgrades for your biology have nothing to do with supplements, nootropics, or the latest biohacking trends.
-Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR
-Learn more about Dr. Abirached’s work at: https://limitlesshuman.ae/
Host Dave Asprey sits down with Dr. Elie Abirached, a Dubai-based longevity and biohacking strategist, Harvard alumnus, founder of Limitless Human, and CEO of Restore Fitness. After being smuggled out of Lebanon during the civil war as a teenager, he built a career helping high performers improve healthspan, resilience, recovery, metabolism, and longevity. Today he is one of the Middle East’s leading voices in biohacking, healthy aging, human performance, sleep optimization, and lifestyle-driven longevity.
Together, they explore why Dubai has become a global hub for biohacking and longevity, how extreme heat, light exposure, fasting, and modern lifestyle habits affect human biology, and why nervous system health may be one of the most overlooked drivers of long-term performance and anti-aging. They also dive into trauma, neuroplasticity, emotional resilience, metabolism, brain optimization, sleep quality, and the hidden programming that shapes your reactions, relationships, and health outcomes.
You’ll discover what the Middle East gets right about health and longevity, why resilience may be one of the most important predictors of healthy aging, and how your environment influences everything from recovery and mitochondria to sleep, energy, and mental performance. This episode offers practical insights for anyone interested in biohacking, human performance, longevity, fasting, sleep optimization, metabolism, brain optimization, emotional resilience, and building a stronger, more adaptable nervous system.
You’ll Learn:
• How childhood experiences and unconscious programming influence longevity, healthspan, and human performance
• Why nervous system regulation may be one of the most powerful anti-aging tools available
• What Dubai’s biohacking community gets right about health, recovery, and longevity
• How fasting, including Ramadan-style fasting, affects metabolism, energy, and performance
• The connection between neuroplasticity, emotional resilience, and brain optimization
• How sleep optimization impacts mitochondria, recovery, aging, and cognitive function
• Why environmental factors like heat, light exposure, air quality, and circadian rhythm matter more than most people realize
• How to improve healthspan without relying solely on supplements, nootropics, ketosis, or the latest biohacking trends
• Why stronger biology creates better decision-making, relationships, and long-term success
• Practical strategies for building resilience in a world filled with stress, distraction, AI, and information overload
Thank you to our sponsors!
- Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.
- Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
- Cowboy Colostrum | Get your gut right by going to cowboycolostrum.com/asprey for 25% off of your entire order.
- Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. Use code DAVE30 for 30% off.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Dr. Elie Abirached, Dubai biohacking, UAE longevity, Middle East biohacking, Lebanon civil war survivor, resilience training, childhood trauma, nervous system regulation, emotional resilience, neuroplasticity, longevity medicine, healthy aging, human performance, sleep optimization, circadian rhythm, Ramadan fasting, intermittent fasting, metabolism optimization, stress adaptation, biological aging, mitochondria health, environmental health, heat adaptation, Dubai longevity, Limitless Human, Restore Fitness, healthspan, recovery optimization, biohacking Dubai, trauma and longevity
Resources:
• Learn more about Dr. Abirached’s work at: https://limitlesshuman.ae/
• Order Dr. Abirached’s Book ‘Limitless Human’: https://a.co/d/0cwoQFRH
• Purchase Dr. Fotuhi’s New Book The Invincible Brain: https://a.co/d/0iHCgPpL
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Trailer
00:50 – War Zone Childhood
04:52 – Dubai Mission
08:08 – Childhood Trauma Programming
13:59 – Biohacking in Extreme Heat
19:37 – Fasting & Ramadan
25:15 – Closing
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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