Afleveringen

  • THE BRAIN IS HUNGRY FOR PEOPLE. Keeping in mind new experiences of isolation during the pandemic, recent research shows parallels between a socially-deprived brain craving people and a fasted brain craving food.

    Full notes at headshake.show/episodes/34

  • Zijn er afleveringen die ontbreken?

    Klik hier om de feed te vernieuwen.

  • The letter A is always red to some people. To others, the sound of a car horn might always smell like pie. Libby and Ruka sensually explore the rare but real condition of synesthesia.

    Full notes at headshake.show/episodes/32

  • Returning to the land of electrophysiology, Lord Nathan and Lady Kristen focus this time on action potentials, which neurons use to send electrical signals long distances in the body. God save the Baked Bean!

    Full notes at headshake.show/episodes/30

  • In 1848, Phineas Gage survived an unfortunate railroad accident that later informed science and medicine’s understanding of how the prefrontal cortex works. Supporting character: Spikey the tamping iron


    Full notes at headshake.show/episodes/29

  • It’s Headshake’s anniversary, and the finale of the Gap Junction Almanac. We hope you’ve had the “Time of Your Life,” and we’ll still be “Friends Forever.” Let’s cheer ourselves up with a discussion of seasonal affective disorder (SAD).

    Key Words

    bipolar ii, circadian rhythm, cognitive behavioral therapy (CBT), depression, heritable, light box, light therapy, lux, major depression, melatonin, norepinephrine-dopamine reuptake inhibitor (NDRI), psychotherapy, seasonal affective disorder (SAD), selective serotonin reuptake inhibitor (SSRI), serotonin, summer pattern, vitamin D, winter pattern

    Old West Word of the Day (Gap Junction Almanac)

    Anglomaniacs

    Lots of old west insults - Listen to the episode for a season finale’s worth of insults

    References and Resources

    NIMH » Seasonal Affective Disorder (nih.gov), National Institute of Mental Health Seasonal affective disorder (SAD) - Symptoms and causes, Mayo Clinic Are You Affected By Seasonal Affective Disorder (SAD)?, Psychology Today ClimaTemps http://www.madison.climatemps.com/sunlight.php https://www.oahu.climatemps.com/sunlight.php Diagnostic and Statistical Manual of Mental Disorders (DSM-5)

    Season 1 Spotify Playlist!

    HEADSHAKE: The Playlist



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    Early Bird Science - Ruka’s other science podcast

    earlybirdscience.com



    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

  • “Nerves?” This is a neuroscience podcast. Haven’t we been talking about nerves the whole time??? Nope! Learn why.



    Key Words

    afferent, anopsia, anosmia, autonomic, axon, cardiac muscle, cardiovascular, caudal, central nervous system (CNS), cervical nerves, coccygeal nerves, cranial nerve, efferent, gastrointestinal (GI), innervate, larynx, lateral, lumbar nerves, mastication, medial, motor, nerve, nucleus ambiguus, peripheral nervous system (PNS), pharynx, ptosis, pulmonary, rostral, sacral nerves, sensory, skeletal muscle, smooth muscle, somatic, spinal nerve, sternocleidomastoid, thoracic nerves, trapezius, trigeminal neuralgia

    CN I - Olfactory CN II - Optic CN III - Oculomotor CN IV - Trochlear CN V - Trigeminal (Divisions: Ophthalmic, Maxillary, Mandibular) CN VI - Abducens CN VII - Facial CN VIII - Vestibulocochlear CN IX - Glossopharyngeal CN X - Vagus CN XI - Spinal Accessory CN XII - Hypoglossal




    Old West Word of the Day (Gap Junction Almanac)

    Zitted

    Zooning



    References

    Textbooks

    Vander’s Human Physiology, 13th Edition Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Fundamental Neuroscience for Basic and Clinical Applications, Haines, 3rd Edition



    Season 1 Spotify Playlist!

    HEADSHAKE: The Playlist



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    Early Bird Science - Ruka’s other science podcast

    earlybirdscience.com



    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts



    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

  • There are two kilograms (4.4 pounds) of microbes in your gut. Are these little residents controlling your brain? If so, how? Poop Detectives Libby and Ruka are on the case.



    Key Words

    autism, bacteria, depression, enteroendocrine, fecal transplant, gamma aminobutyric acid (GABA), gastrointestinal (GI) system, gut flora, gut microbiome, immune cells, inflammation, irritable bowel syndrome (IBS), kynurenine, neuropod cells, Parkinson’s disease, psychobiome, psychobiotics, schizophrenia, serotonin, tryptophan, Valsalva maneuver



    Old West Words of the Day (Gap Junction Almanac)

    Yack

    Yam



    References and Resources

    Meet the ‘psychobiome’: the gut bacteria that may alter how you think, feel, and act, Science Magazine, May 7, 2020



    Season 1 Spotify Playlist!

    HEADSHAKE: The Playlist



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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts



    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

  • Hair cells in your inner ear and piano keys in your brain. This is our second episode on the sense of hearing. Libby and Ruka wrap up the year with thicker-than-usual Wisconsin accents. Happy birthday to Libby, and Happy New Year!



    Key Words

    amplitude, auditory cortex, basilar membrane, brain stem, calcium, cochlea, cochlear duct, cocktail party effect, cranial nerve viii (vestibulocochlear), decibels, depolarization, frequency, gating, glutamate, hair cells, helicotrema, inner hair cells, mechanically-gated, neurotransmitter, organ of Corti, outer hair cells, oval window, pitch, potassium, receptor, round window, scala tympani, scala vestibuli, stapedius, stapes, stereocilia, synapse, tectorial membrane, tensor tympani, thalamus, threshold of pain, tinnitus, tip link, vesicles, voltage-gated



    Old West Word of the Day (Gap Junction Almanac)

    weather breeder

    wabble



    Related Episodes

    Lime in the Cochlea [Audition, Part 1]



    Reference

    Textbook: Vander’s Human Physiology, 13th Edition



    Season 1 Spotify Playlist!

    HEADSHAKE: The Playlist



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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

  • This is part one of two episodes about the auditory system. You could say it’s a “preliminary hearing.”

    Key Words

    amplitude, audition, auditory system, aurical, cochlea, cochlear duct, deaf, decibel, eardrum, endolymph, eustachian tube, external auditory canal, frequency, hearing impaired, hearing, helicotrema, incus, inner ear, malleus, middle ear, organ of Corti, outer ear, oval window, perilymph, pinna, pitch, round window, scala tympani, scala vestibuli, stapes, tympanic membrane, volume, zone of compression, zone of rarefaction

    Old West Words of the Day (Gap Junction Almanac)

    Wearing the bustle wrong

    Wipe your chin

    BRAND NEW Season 1 Spotify Playlist!

    HEADSHAKE: The Playlist

    Reference

    Textbook: Vander’s Human Physiology, 13th Edition

    Connect with us!

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

  • Bad news/good news: Grand mal got run over by a reindeer, BUT we got new microphones! In addition to learning what science does and doesn’t know about brain lightning storms (seizures), hear Libby’s seasonal reflections on the Little Drummer Boy.

    Key Words

    absence, amygdala, anticonvulsant, apoptosis, atonic, aura, benzodiazepine, carbamazepine (Tegretol), cellular signaling cascade, clonic, complex, cortex, cyanotic, diazepam (Valium), electroencephalogram (EEG), epilepsy, excitotoxicity, GABA, GABAA receptor, generalized, glucose, glutamate, grand mal, hippocampus, inhibitory surround, kindling, limbic, lorazepam (Ativan), magnetic resonance imaging (MRI), metabolism, motor, myoclonic, necrosis, negative symptom, occipital, oxygen, partial (focal), petit mal, phenytoin (Dilantin), piloerection, plasticity, positive symptom, positron emission tomography (PET), postictal, primary, secondary, seizure, sensory, simple, single photon emission computed tomography (SPECT), status epilepticus, symptomatic epilepsy, tonic, tonic-clonic, visual

    54 key terms!

    Old West Words of the Day (Gap Junction Almanac)

    vum

    vaultinghouse

    References and Resources

    Textbooks

    Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Vander’s Human Physiology, 13th Edition

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your medical provider before making decisions about your health.

  • Who are you?! Oh, right. Hi, Jeff! Sorry about that. Our forgetting neurons were working particularly hard last night. Yes, you have neurons that make you forget. Turns out they’re important in memory.

    This Episode’s Spotify Playlist

    Neuralized

    Key Words

    action potential, amygdala, anxiety, appetite, CA1, calcium transients, chemogenetics, consolidation, contextual fear conditioning (CFC), cued fear, dreams, electroencephalogram (EEG), electromyography (EMG), electrophysiology, fiber photometry, forget, GABA, GABA-ergic, glutamate, hippocampus, hypothalamus, immunohistochemistry, inhibitory post-synaptic current (IPSC), limbic, melanin-concentrating hormone (MCH) neurons, memory, microendoscopy, novel object recognition (NOR), optogenetics, retention, retrobeads

    Old West Word of the Day (Gap Junction Almanac)

    Unsalted

    References and Resources

    Primary research paper: REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories, Science, 20 Sept 2019 “Kid’s Menu:” Scientists Find The Neurons That Make Your Brain Forget

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • IN CASE OF EMERGENCY BREAK GLASS. Libby and Ruka are busy or dead. Either way, you get to listen to this episode recorded as a backup for times like these. Hear their joy, and remember them as they were before the pandemic.

    Key Words

    boredom susceptibility, cortisol, disinhibition, dopamine, experience seeking, mindfulness, norepinephrine, sensation seeking, thrill and adventure seeking, zorbing

    The big five:

    Openness to experience Conscientiousness Agreeableness Extroversion Neuroticism



    Old West Words of the Day (Gap Junction Almanac)

    Balls, Beef, Biff



    Reference

    Lust for Life, Psychology Today, October 2019

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • Headshake’s personal chef (a.k.a. Ruka’s spouse) is also an electrical and electronic engineer. Steven A. Gago helps Libby and Ruka tackle the mysteries of newly-developed microcircuit chips that could one day become implants to replace diseased neurons.

    Key Words

    Alzheimer's, analog, assimilate, bioimplant, Bötzinger region, brain stem, bursts, CA1, chip, circuit, current, digital, hardware, hippocampus, Hodgkin-Huxley model, medulla, model, pyramidal cells, respiratory neuron, solid state neuron, soma, transistor, very-large-scale integration (VLSI)

    Old West Words of the Day (Gap Junction Almanac)

    There you ain’t

    Teapot

    Tin

    Toad strangler

    References and Resources

    Artificial neurons developed to fight disease, BBC, December 2019

    Optimal solid state neurons, Abu-Hassan et al, Nature Communications, December 2019

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • In this elephant-themed episode, Headshake’s male and female hosts talk about whether or not there are differences in the brain between the sexes. If there are, how do they get there, and do they even matter?

    Key Words

    ADHD, autism spectrum disorder, behavior, conduct disorder, corpus callosum, development, eating disorders, environmental, frontal lobe, gender, generalized anxiety disorder, genes, hormones, hypothalamus, innate, intersex, major depression disorder, parietal lobe, phrenology, plasticity, sex, social

    Old West Words of the Day (Gap Junction Almanac)

    shote

    skittles

    slamgander

    slantindicular

    see the elephant

    saltwater vegetables

    References and Resources

    Brain scientists haven’t been able to find major differences between women’s and men’s brains, despite over a century of searching, The Conversation, August 6, 2020 Neuroscience and Sex/Gender: Looking Back and Forward, The Journal of Neuroscience, January 2, 2020

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • Does listening to Headshake activate your fight or flight response? Or maybe it leaves you comfortably in your rest and digest state. Ruka and Libby talk about the differences between these systems while planning Libby’s self-eulogized Viking funeral.

    Key Words

    acetylcholine, adrenal medulla, adrenaline, afferent, autonomic motor, autonomic nervous system, blood pressure, central nervous system (CNS), cervical, collateral ganglia, efferent, enteric, epinephrine, fight or flight response, ganglion, gastrointestinal (GI) tract, glucose, heart rate, heart, homeostasis, innervate, liver, lumbar, norepinephrine, parasympathetic, peripheral nervous system (PNS), postganglionic, preganglionic, pupils, rest and digest state, sacral, somatic motor, somatic nervous system, somatic sensory, special sensory, spinal cord, stress, sympathetic trunk, sympathetic, thoracic, visceral sensory

    Old West Words of the Day (Gap Junction Almanac)

    Rumbumptious

    Rum hole

    References and Resources

    Textbook: Vander’s Human Physiology, 13th Edition

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • Want to lose 1.5 pounds fast? Get a hemispherectomy! Libby and Ruka discuss research on highly-functioning adults who, for medical reasons, had half their brains removed as kids.

    Key Words

    anatomical hemispherectomy, behavior, brain stem, cerebellum, cerebrum, chronic focal encephalitis, cognition, connectome, control/executive, cortical dysplasia, default, dorsal attention, emotion, functional hemispherectomy, intelligence, functional network, hemispherectomy, limbic, parcel, perinatal stroke, plasticity, Rasmussen encephalitis, salience/ventral attention, somatosensory/motor, visual

    Old West Word of the Day (Gap Junction Almanac)

    Quincy

    Bonuses: puddin’ foot, prairie chips, pop your corn

    References and Resources

    Research Paper: Intrinsic Functional Connectivity of the Brain in Adults with a Single Cerebral Hemisphere Related articles How The Human Brain Rewires Itself After Half A Hemisphere Is Surgically Removed What Is Brain Plasticity And Why Is It So Important?



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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • Libby and Ruka learn about the strange but harmless experience of being awake and not being able to move. This episode is brought to you by the letter P and delicious chocolate frosted Kooky Monkey Brains: “They’re mentally delicious.”

    Key Words

    atonia, brain stem, general anxiety disorder, glycine, hallucinate, interneurons, jet lag, medulla, midbrain, narcolepsy, non-rem, panic disorder, pons, post traumatic stress disorder (PTSD), rapid eye movement (REM), REM-off, REM-on, shift work, sleep offset paralysis, sleep onset paralysis, sleep paralysis, sleep phase, spinal cord

    Old West Word of the Day (Gap Junction Almanac)

    Piece of pudding

    Pecker pole

    References and Resources

    Sleep Paralysis and the Monsters Inside Your Mind, Scientific American Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Sleep Paralysis, NHS

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.

  • In an attempt to recover from the last episode’s derailment by boy bands, Ruka speeds through an overview of the hypothalamus and the anterior pituitary. In the process, she discovers Libby’s deep past with the movie Cool Runnings.

    Key Words - New record: 46!

    adrenal cortex, adrenaline, adrenocorticotropic hormone (ACTH), anterior pituitary, biogenic amine, catecholamine, corticotropin, corticotropin-releasing hormone (CRH), dopamine, endocrine feedback loop, epinephrine, estradiol, follicle-stimulating hormone (FSH), germ cell, gonadotropin-releasing hormone (GnRH), gonadotropins, gonads, growth hormone (GH), growth hormone release inhibiting hormone (GHRIH), growth hormone-releasing hormone (GHRH), homeostasis, hypothalamo-pituitary-adrenal (HPA) axis, hypothalamo-pituitary-gonadal (HPG) axis, infundibulum, insulin-like growth factor 1 (IGF-1), luteinizing hormone (LH), median eminence, melanocyte, melanocyte-stimulating hormone (MSH), melanocyte-stimulating hormone release-inhibiting factor (MIF), melanocyte-stimulating hormone-releasing factor (MRF), ovaries, ovum, parvocellular neurons, peptide hormone, portal vasculature, progesterone, prolactin, somatostatin, sperm, testes, testosterone, thyroid-stimulating hormone (TSH), thyrotropin-releasing hormone (TRH), thyroxine, triiodothyronine

    Old West Word of the Day (Gap Junction Almanac)

    Oof

    Related Episode

    Episode 14: Turkey Saddle [Hypothalamus and Posterior Pituitary]

    References and Resources

    Textbooks

    Vander’s Human Physiology, 13th Edition Principles of Neural Science, Kandel, Schwartz, and Jessell, 4th Edition Fundamental Neuroscience for Basic and Clinical Applications, Haines, 3rd Edition

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    Music

    Bushwick Tarantella by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/)

    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300002

    Artist: http://incompetech.com/

    Modified from original with volume fading and cuts

    Disclaimer

    This podcast is for entertainment and education only. Neither of the hosts is a medical doctor, and nothing they say is medical advice. Please consult with your physician before making decisions about your health.