Afleveringen
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The light we see is as crucial as the food we eat, the water we drink, and the air we breathe. Former Harvard Medical School professor and 40-year leading expert in circadian clocks and human health, Dr. Moore-Ede speaks on why our health hinges on getting the right sort of light at the right time.
In this episode, he reveals the dangers of modern LED lighting, which often emits bright but unhealthy "junk light." Just as junk food wreaks havoc on our body, junk light disrupts our circadian rhythms, suppresses melatonin, and contributes to chronic diseases.
We cover:
💤 The Health Risks of LED Lighting: "junk light" disrupts circadian rhythms, suppresses melatonin, and contributes to chronic diseases
💡 Junk Light and Lumens - modern lighting regulations prioritise energy efficiency over human health
🕒 Circadian Clocks and Longevity: light is essential for disease prevention and healing
👓 Rise of Myopia in Children: indoor living and reduced exposure to natural light are fueling skyrocketing rates of myopia
🌈 Blue light blocking glasses - do you have the right sort?
🛠️ Practical Solutions for Healthier Lighting: simple changes you can make in your home and your life
Backed by decades of evidence, Dr Martin Moore-Ede shares the science behind why we must prioritise light in our health, and how to optimise our exposure for immediate benefits, and a longer, healthier life.
Find Dr Martin:
Book: https://thelightdoctor.com/
Website and Campaign
Substack
LinkedIn
Instagram
Twitter
YouTube
Google Scholar
Mentioned in this episode:
Health and Light by John Ott
SORAA - light bulbs
The Body Electric by Robert Becker and Gary Seldon
Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort
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Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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Here we're speaking with Dr. Joseph Cullen as he discusses his research on high dose intravenous (IV) vitamin C as a treatment for metastatic cancer. The aim in his lab is to show that adding high-dose, IV vitamin C, which is very inexpensive and very well tolerated, can improve treatment for these cancers that are among the deadliest. Joseph highlights the potential for it to transform not just patient outcomes but the entire conversation around alternative therapies. He shares candid insights from his lab’s work on glioblastoma, lung cancer, and pancreatic cancer, as well as ongoing studies into combining vitamin C with other treatments like immunotherapy and radiation.
We cover:
💡 What makes high-dose IV vitamin C a game - changer in cancer care
📈 Cancer progression and survival outcomes - his research that shows doubling progression-free survival
🔍 Mechanisms of action - pro-oxidant in cancer cells, antioxidant in healthy cells
👩⚕️ Challenges in acceptance - why some oncologists remain skeptical
🩺 Who benefits most - which cancers respond best, combining therapies, and where it doesn’t work
⚠️ Side effects and safety - what to watch for, including rare risks
The research shows significant promise, but challenges persist. Joseph opens up about the difficulties in securing funding for anything outside pharma-driven drugs and compounds, the skepticism from traditional oncology, and the need for more extensive clinical trials to validate findings. Despite these hurdles, his belief in the therapy’s potential remains steadfast - and his surprise at just how well it works, over and over again, keeps driving him forward.
Mentioned in this episode:
High-dose IV vitamin C plus chemotherapy doubles survival in advanced pancreatic cancer
A randomized trial of pharmacological ascorbate, gemcitabine, and nab-paclitaxel for metastatic pancreatic cancer
What is metastatic pancreatic cancer?
Find Joseph:
[email protected] - Joseph kindly said that oncologists can reach out to him directly to enquire more and request the protocol for patients where appropriate
All Dr Cullen’s papers
Free Radical & Radiation Biology
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Disclaimer
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Zijn er afleveringen die ontbreken?
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Meet Professor Thomas Seyfried, the biologist leading a revolution in how we fight cancer and other chronic diseases with metabolic therapies. Author of the acclaimed book 'Cancer as a Metabolic Disease', Professor Seyfried talks through the evolutionary biology behind cancer and the scientific evidence that disproves the consensus theory on the origin of cancer. His focus on the need for mitochondrial health and metabolic therapies opens up the conversation for new avenues of treatment that are less toxic and, quite possibly, more effective.
We cover (+much more):
🥬 How cancer cells thrive on fermentation - and how this changes treatment approaches
📉 The future of cancer care - rethinking research, funding, and patient education
🥩 Ketogenic diets and cancer
💊 Glutamine inhibitors and parasite drugs - tools with potential in fighting metastatic cancer
⚠️ The cost of traditional care - understanding why metabolic therapies may work better than or in addition to SOC
🌍 Why mitochondrial health matters – for cancer, diabetes, Alzheimer’s, and more
Professor Seyfried is astounded by how many cancer patients start to use metabolic therapy only after they've exhausted all other options and they haven't worked. He believes the first thing you need to do is get your body into NK, whatever treatment you choose. For patients, researchers, and anyone interested in the future of cancer care, this episode presents the latest metabolic science and the latest framework for cancer prevention and treatment strategies.
You have to ask - are we literally tripping over the truth here?
Find Thomas:
Website
Twitter
YouTube
Book - Cancer as a Metabolic Disease
All of Professor Seyfried's published work
Mentioned:
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer
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Instagram @degreesofhealth
Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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LJ Amaral dives us deep into the world of metabolic therapies and the ketogenic diet as a potential treatment for cancer. LJ shares valuable insights into the promising intersection of diet and cancer care and her pioneering research in the field makes this a must-listen for anyone interested in personalised cancer treatments and improving quality of life through dietary changes.
We cover (but so much more too):
📖 The Warburg theory - understanding a cancer cells’ glucose dependence
🥑 Getting the fat equation right - omega-3s, whole fats, and tips for sticking to a high-fat diet. And why fat matters more than protein here...
🫒 Keto vs. Keto for cancer - dramatic tumour reductions and improved patient-reported outcomes in fatigue and cognition
💡 Future research - ketosis thresholds, 428 ongoing clinical trials, and personalised metabolic therapies
🩺 Patient-centered care in cancer treatment - respecting choices while providing evidence-backed support
🌟 BHB and inflammation - how ketones stabilise damaged cells and improve outcomes
LJ Amaral’s commitment to extending healthspan and improving quality of life shines through. Her belief in the importance of maintaining hope and collaboration between patients and clinicians is inspiring.
Find LJ:
Research Gate
Mentioned in this episode:
Keto Nutrition.org - also see our episode with Dom D’Agostino
Charlie Foundation
Keto Mojo by Miriam Kalamian
Tools of Titans by Tim Ferriss
Untethered Soul by Michael Singer
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Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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What if the way we think about mental health is due for a revolution? Maybe we don’t need to suffer and to 'try to' live well with the big challenges that mental illness can bring - maybe we can actually...live well.
In this deeply personal and groundbreaking conversation, Lauren Kennedy-West shares her experience of living with schizoaffective disorder - and historical diagnoses that included depression, bipolar disorder with psychotic features, and an eating disorder - to living symptom-free and off psychiatric medications. What she did? After years of psychotic episodes, anti-depressants, and anti-psychotics, Lauren made a decision not centred on treating the symptoms but on improving her underlying metabolic health. Lauren adopted a strict medical ketogenic diet and metabolic therapies that healed her brain and transformed her life.
What if we removed the dogma on how we currently understand mental health - for just a moment - and were to ask 'what if we are wrong?' - what might we be able to see? Heads you win big, tails you don’t lose much. And in Lauren's case, she won big
We hope this episode serves as a safe space to explore ideas that may challenge the status quo and offer immense hope for anyone thinking "there must be something more I can do". There is. Lauren's story provides powerful insights into what is possible when we address the root causes of mental illness, serving as a beacon of hope and inspiration as to what is possible for a better tomorrow.
Find Lauren:
Website
YouTube
Instagram
Online peer support communities:
Metabolic Therapies for Mental Disorder
Schizophrenia Peer Support Community
Additional resource for Metabolic Therapies for Mental Health:
Metabolic Mind website
Metabolic Mind YouTube channel
Mentioned in this episode:
Gut and Psychology Syndrome by Natasha Campbell-McBride
Brain Energy by Chris Palmer
Chronometer App
Dr. Guido Frank
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Instagram @degreesofhealth
Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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Dr. John Mulhall doesn't just treat erectile dysfunction (ED), he's also on a global mission to demystify its causes, highlight its complexities, and offer an alternative to how we currently think about sexual health.
This is for you if you’re wondering: what can I do today to ensure better sexual health tomorrow? Even if it's good today, don't you want to ensure it'll be good in your later years? And if it's not where you want it to be today, perhaps you've not spoken to anyone about it yet - you're not alone here. There are answers out there and support to be given. But you've got to ask for it.
We cover:
🏃 Exercise and erectile health - getting it up (your heart rate)
📈 Durability and frequency - it matters, but it should only matter to you
👨⚕️ Exogenous testosterone - risk of transference and its impact on fertility
💦 Premature ejaculation: lifelong vs. acquired - and what to do about each
💉 Navigating treatment options - pills, patches, and injectables and caution over the the ‘Wild West’ of supplements
💊 PDE5 inhibitors - how they work, their cardiovascular benefits, and their limitations
🧠 The psychology behind ED - how placebos enter in and integrating psychological and medical approaches for effective treatment
🔬 Emerging therapies - shockwave therapy, platelet-rich plasma, and penile botox injections - do they work?
His ultimate advice? Don’t wait to bring it up. Whether you’re a patient or a physician, empowering conversations can make all the difference.
Find John:
Twitter (@SaveYourSexLife)
Dr John's Book
Want to watch this on video? Subscribe on YouTube
Instagram @degreesofhealth
Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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Just how judgey are we when it comes to sex? With ourselves, with our partners, with friends, when listening to others online... Be honest. What benefit does it serve? Or a better question to ask perhaps is what damage might it be doing?❗Whether you’re navigating your own relationship challenges or seeking deeper insights into your own sexual exploration, listen here to Dr Kate because it's a rich and honest conversation that might just reshape how you think about and experience intimacy, equality, and desire.
Dr. Kate, who has spent thousands of hours with individuals and couples in private practice, shares with us the complexities of sexual struggles that are often silenced. And what's most sad to Dr Kate is just how many people tolerate dissatisfaction in their relationships, and never experience the full potential of their intimate capacity.
We unpack a lot in this episode:
🤨 Can we trade out judgement for curiosity when it comes to ... well everything, but sex in particular?
🪝 Hook up culture - what happens when we only focus on individual rather than shared pleasure?
🖋️ Better sex education (not excl. anatomy + pleasure) and pleasure equity
👨 The challenges men face in being emotionally present balanced with still proving that they check all the boxes of 'what it means to be a man'
🍼 How intimacy evolves and changes (!) over time, the inequities of emotional labor and discrepancies in desire
Some tougher topics to face: --Why do happy people cheat? --How do trauma and dissociation impact intimacy? --What does it take to create the psychological and emotional space necessary for genuine connection?
Dr. Kate is relentlessly positive in her regard and nothing is off the table to explore. She shares actionable advice on how couples can work at building shared realities, breaking down barriers to arousal, and cultivating a sense of safety and play.
Mentioned in this episode:
She Comes First by Ian Kerner (see previous episode with Ian)
Come As You Are - Emily Nagoski
Kate Mann - Down Girl; Entitled
The Patriachs by Angela Saini
Everyday Sexism - Laura Bates
Yes, Mistress by Alicia Zadig
Find Kate:
ModernIntimacy.com
Instagram
Podcast: Get Naked with Dr Kate
Book release Feb 2025 - What Happened To My Sex Life?
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Instagram @degreesofhealth
Disclaimer
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This episode's information revealed just how much of our 'regulated' nutritional information is either completely outdated or incorrect. Here with Lily Nichols, a renowned dietitian and author who is not afraid to speak on the controversial dietary topics, we discuss where current nutritional guidelines on protein and micronutrients impact overall health and hold us back, particularly for those looking to optimise fertility and metabolic health.
Tune in to get the latest on:
🤰 Nutritional foundations for maternal and child health - pre-pregnancy, pre-natal, and post natal
🍩 Blood sugar regulation and nutrient-dense diets for prospective parents
ℹ️ The actually essential roles of non-essential amino acids
👶🏻 A protein-forward, nutrient dense intake for maternal health and fetal development
🌾 Supplementing vs real foods - the synergies
🧬 How nutrients (like choline, vitamin D, and B12) influence genetic expression from the womb onward
This conversation is a must for prospective parents, and anyone seeking to understand how optimal nutrition intersects with fertility, energy, and lifelong health.
Find Lily:
Website, Blog Posts and Books
Free 1st Book Chapter - Real Food for Pregnancy
Instagram
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Instagram @degreesofhealth
Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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A powerhouse of knowledge, we're joined by Dr. Casey Peavler who invites us to address 3 impending needs: 1. for medicine to become less siloed 2. for doctors never to stop learning or being curious and 3. for patients to not lose their autonomy and agency in health treatments and decisions. Here, Ben and Dr Casey delve into the evolving understanding of cancer treatment, contrasting the traditional somatic mutation theory with the emerging metabolic theory of cancer. The conversation highlights the intricacies and nuances of new and promising routes to understand cancer and its treatment to remission. As with many of our conversations and guests, Casey emphasises the importance of patient agency and the need for informed decision-making in collaboration with healthcare providers.
We discuss:
🥼 Somatic vs. Metabolic Theories of Cancer - why our understanding of cancer needs to evolve and where they both have merit
🤏The Press Pulse Protocol - “starving” cancer cells while strengthening the body
🥥 Exogenous Ketones, Glucose, and Glutamine — Targeting cancer cells’ energy sources for effective treatment
🔅 Chronic low-level sun exposure for Vitamin D - crucial for both cancer prevention and treatment
💊 Dosing strategies - daily dosing of certain medications may be more effective than intermittent dosing for cancer treatment but context is key
🙋 The Power of Patient Agency — Moving from passive recipient to active participant in cancer care
Dr. Peavler urges patients to 'take the wheel' in their health journey. This conversation we hope will inspire you to explore all the avenues available to us when it comes to health, emphasising that you never lose the opportunity to be an agent within your own care - get information, learn, gather resources and identify what looks like a path to health for you. And we'd love to hear from you if you do.
Find Casey:
Integra Medicine
YouTube
Mentioned in this episode:
Books by Dr Fung - The Cancer Code. The Obesity Code.
Study Douglas Wallace
Study Press-pulse: a novel therapeutic strategy for the metabolic management of cancer
Book Defeating Cancer!: The Biological Effect of Deuterium Depletion by Gabor Somlyai
Book The Plant Paradox by Stephen Gundry
Book Keto Fast by Joseph Mercola
Book - Cancer as a Metabolic Disease by Thomas Seyfried
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Instagram @degreesofhealth
Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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More keto! We're interested in everything keto at the moment. The different ways to get into ketosis, how the body and brain respond to a ketogenic state, the complexities of exogenous ketones, and what possible benefits and drawbacks a state of ketosis has.
Dr. Brendan Egan this week helps us to dissect the current literature of ketones within the field of exercise performance and recovery, and offers a suggestion to look past ketones as a one-size-fits-all solution. Brendan also shares insight on the future of ketone research and the importance of focusing on foundational health practices.
We cover:
🥜 Natural ketosis - fasting and/or a ketogenic diet
🧪 Exogenous ketones explained: ketogenic precursors (MCTs), salts, esters, and dosage
🔬 The current data on ketosis and performance / recovery - the promising and the no-shows
😟 The potential value of ketosis when the body is really stressed
💪 Muscle protection - mitigating the effects of bed rest
💊 Placebo Power: Impacts performance and supplement perception.
If you're interested in using keto as a dietary intervention for exercise performance, recovery, or as a protective mechanism with reduced mobility or bed rest, have a listen. It certainly could be worthwhile seeing if shifting your body's fuel source helps you in your endeavour.
We'd love to hear from you - have you had any personal results that demonstrate anything similar to or contrary to the current literature?
Mentioned in this episode:
Study Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes
Study Ketone Bodies Attenuate Wasting in Models of Atrophy
Book Outlive by Peter Attia
Book Surely You’re Joking and What Do You Care What Other People Think? by Richard Feynman
Herology Women's Supplements
Find Brendan:
Email
Google Scholar
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Instagram @degreesofhealth
Disclaimer
Hosted on Acast. See acast.com/privacy for more information.
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Why are we scheduling dentist appointments but not sex? How do we tackle desire discrepancies—when one of us is in the mood while the other is wondering what’s on Netflix? And why is "performance anxiety" such a thing?!
Ready to dive into the nitty-gritty of what really makes relationships tick? We sit down with Ian Kerner - he’s got the answers to all those questions you probably didn’t ask at your last dinner party. From how common it is for couples to be inches apart physically but miles apart emotionally, to the very real consequences of deprioritising sexual attraction, this conversation is a masterclass in sex and intimacy.
We go into:
📢 Why sexual compatibility should be a top priority in relationships
🪜 Bridging the gap in desire differences
⏰ Performance anxiety and the male obsession with "lasting longer"
👑 The clitoris as queen: closing the orgasm gap
📅 Scheduling sex: Unsexy or genius?
👴👵 Keeping the flame alive in long-term relationships
We see all of you out there experiencing this and not asking the questions. So we did it for you. You're welcome! Watch, listen, take note, maybe even try a new approach. Whether you're in a relationship, looking for one, or just curious, this conversation might start you thinking that there's another way to think about sex for your relationship health - and it could just be better than what you've got now...
And let us know - what do you think? What other questions do you have? "Is it normal that...?" Has it helped? Are there more obstacles?
Find Ian:
Website
Mentioned in this episode:
She Comes First by Ian Kerner
So Tell Me About the Last Time You Had Sex by Ian Kerner
The Erotic Mind by Jack Morin
Study - More Than Just Sex: Affection Mediates the Association Between Sexual Activity and Well-Being
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Instagram @degreesofhealth
Disclaimer
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This podcast episode features an in-depth conversation on metabolic therapies and their potential in cancer treatment, particularly focused on glioblastoma and other glycolytic cancers. Our guest, Dr Dom D'Agostino, a researcher and professor with a diverse background in neuroscience, molecular pharmacology, nutrition and physiology, has a particular interest in metabolic therapies. Dr Dom shares how manipulating the body’s metabolism through the glucose ketone index (GKI), therapeutic ketogenic diets, and redox therapies can improve cancer outcomes by reducing tumour growth and enhancing standard treatments like chemotherapy and radiation. We also explore the synergies of non-toxic therapies such as hyperbaric oxygen, metformin, and IV vitamin C, and how these could potentially reduce the side effects and overall outcomes of cancer treatment.
We cover:
🩺 Standard cancer care with and without metabolic interventions
💊 Managing seizures with ketogenic therapies - a superior alternative to anti-seizure drugs
🍽 The power of fasting and the importance of protein intake in chemotherapy and cancer augmentation
🔥 Why certain cancers are more susceptible to metabolic-based therapies
🔬 How overall mitochondrial health dictates cancer cell transformation
Dom also touches on the fundamental relationship between liver health and cancer growth and metabolic strategies to prevent cancer. If you're interested in the intersection of nutrition and cancer or wondering how far we are from keto becoming part of standard care, this is a must-listen episode.
Find Dom:
Website
Metabolic Health Summit
Metabolic Health Summit YouTube
Mentioned in this episode:
Cancer cases attributable to potentially modifiable risk factors
Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy
Ketones inhibit mitochondrial production of reactive oxygen species
The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer
Metabolic management of glioblastoma ...with a restricted ketogenic diet
Clinical trials in progress
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Are you struggling with hair loss and not sure where to start? Or perhaps you have a hormone profile back that you want to work to improve? Whether you’re dealing with hair loss, want to optimise your hormonal profile towards a specific goal, or just want to feel at your best, this episode is packed with a science-backed medical perspective to provide you with the information to make decisions that support your journey to better health.
James O'Hara, a nurse practitioner with a keen specialisation in preventative medicine, explores the science behind hair loss, hormonal balance, and how lifestyle choices impact these areas, and our overall well-being. If you’re seeking practical solutions for improving both your vitality and appearance, this episode is for you.
Key Discussion Points:
🔍 Root causes of hair loss – from iron deficiency to hormonal imbalances in men and women
⚖️ Balancing hormones and hair loss treatments – exploring total testosterone, DHT, dutasteride and finasteride
📚 Stacking for regrowth – combining lifestyle changes with other interventions e.g. microneedling, nutrient optimisation, red light
🥗 Diet and testosterone – how fat, carbs, and supplements can influence hormone levels
🔄 Testosterone Replacement Therapy (TRT) – who might benefit, and the risks involved
🧠 Cognitive Performance – Enhancing brain function with caffeine, Modafinil, and other low-risk tools
James emphasises the importance of a holistic approach, reminding us that no single treatment fits all. It’s about personalisation according to the individual, stacking therapies, managing lifestyle, and optimising nutrition for desired health outcome and long term well-being.
Find James:
Instagram
Gillet Health Podcast
Website
Mentioned in this episode:
Study - Acute administration of roflumilast enhances sensory gating in healthy young humans
Study - Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults
Study - Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals
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PART 2! If you or someone you love is affected by Alzheimers, this is for you. If you believe you’re at risk genetically or you want to prevent your own cognitive decline, this is also for you. If you’re curious about the role of ketones and the ketogenic diet in brain health, this is absolutely for you.
Find Mary Newport:
Website and Books
Mentioned in this episode:
Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease
Dr Stephen Cunane. Can Ketones Help Rescue Brain Fuel Supply in Later Life?
Low-fat versus ketogenic diet in Parkinson's disease:
Study due 2025: Refueling the post COVID-19 brain: potential role of ketogenic medium chain triglyceride supplementation: an hypothesis
A short history of saturated fat: the making and unmaking of a scientific consensus
Lauric acid promotes neuronal maturation mediated by astrocytes in primary cortical cultures
Metabolical by Robert Lustig
Cancer as a Metabolic Disease by Thomas Seyfried
Ravenous by Sam Apple
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PART 1! If you or someone you love is affected by Alzheimers, this is for you. If you believe you’re at risk genetically or you want to prevent your own cognitive decline, this is also for you. If you’re curious about the role of ketones and the ketogenic diet in brain health, this is absolutely for you.
Dr. Mary Newport, neonatologist, author and certified Ketogenic Nutrition Specialist, shares her personal story of using a ketogenic diet to support her late husband, Steve, in his battle against early-onset Alzheimer’s. She explains the science behind ketones and how they serve as an alternative fuel for the brain. This episode doesn’t only offer insight into how ketones can improve cognitive function, mood, and overall quality of life, it also provides a very valid explanation for how they can be used to improve already existing cognitive decline.
We cover (but so much more too):
🧠 The brain-energy gap – how ketones bridge the gap
🥥 MCT oil and coconut oil – their structures and unique role in producing ketones
🍼 The connection between MCTs in breast milk and infant brain development
🔥 Ketones: anti-inflammatory, appetite-suppressing, and brain-protective properties
🩺 Can ketones prevent Alzheimer’s in high-risk individuals?
🔬 Research on ketone esters and future treatments for cognitive decline
Dr. Newport also touches on the need for more research into the use of ketones for Alzheimer's, the impact on inflammation and cerebral blood flow, and the challenges to traditional low-fat dietary guidelines. She emphasises the potential of ketogenic diets to improve brain health both in slowing the development of Alzheimer's and as a preventative measure, and discusses her upcoming book on dietary guidelines and brain ageing.
Find Mary:
Website and Books
Mentioned in this episode:
Reference list on Mary Newport's website
Full reference list can be found in Part 2
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If you feel like life is slipping by and you're unsure how to live with purpose or intention, this episode is for you. William B. Irvine - author, philosopher, teacher and practicing Stoic - shares profound insights on how Stoicism offers a coherent framework for living a fulfilled life. Bill encourages us to embrace discomfort, fail forward, and live authentically—not for social approval but for personal fulfilment. Whether you're new to Stoicism or a seasoned practitioner, this conversation offers actionable insights to help you master the art of living well.
🧠 The psychology of Stoicism: controlling negative emotions, not avoiding all feelings
⚖️ Hedonic treadmill: why chasing happiness may not lead where you think or want
🎯 Living by your values: how Stoicism and Zen Buddhism align in focusing on what truly matters
🌀 Negative visualisation: a Stoic practice for cultivating gratitude and perspective
🔄 Reframing challenges: using a positive mindset to turn obstacles into opportunities
Listen in here if you are interested in carefully rethinking the assumptions of everyday life and how they affect all realms of your health.
Find Bill:
Website
Mentioned in this episode:
Book - A Guide to the Good Life: The Ancient Art of Stoic Joy by William B. Irvine
Book - On Desire by William B. Irvine
Book - The Stoic Challenge: A Philosopher's Guide to Becoming Tougher, Calmer, and More Resilient by William B. Irvine
Book - Walden by Henry David Thoreau
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Mental health - we all have it. Yep, even you.
We are all getting so good at looking after the various aspects of our physical health - nutrition, types of exercise, light exposure, cold baths - whatever your bag is, we're here for it. And many are catching on that the same approach can be used to look at aspects of our mental health. There are things we know make us feel great and then things we do that make us feel... well, not so great. We're human and we have and will continue to get that balance wrong a lot. But we believe part of getting it wrong a little less is being aware of what those things are. Enter the world of therapy that can help us with this process of discovery, identification and support in understanding our rationale behind behaviours that no longer serve us present day and illuminating a world in which we might be able to make differences choices.
Here, we're speaking with Dr. Mitesh Patel discussing mental health and psychiatry. Mitesh talks about the pyramid of sound foundational principles - what we can do to foster sound mental health - and offers a unique perspective of what this field of work is highlighting at the moment. We cover:
💭 Mistruths around what it means to mentally well
💛 Emotional language mapping for young children in schools
🚫 Social media diets
🥽 The future of psychiatry - in-person, telehealth therapy, VR therapy
🛠️ Psychedelics for positive change - micro dosing, assisted therapies, guided trips
Find Mitesh:
LinkedIn
Mentioned in this episode:
*Study - Interconnected Dynamics of Sleep Duration, Social Media Engagement, and Neural Reward Responses in Adolescents
Film - Her
Film - Ready Player 1
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If you use a red or near-infra red light and you don’t really know why or what wave length you’re working with - this is for you. If you don’t even know why you would use a red light or want/need exposure to it, this is also for you.
Glen Jeffery Professor of Neuroscience at UCL, explains the profound impact of light on our cellular health, particularly through the lens of mitochondria—the energy powerhouses of our cells. He explains how different wavelengths, especially red and near-infrared light, can recharge these cellular batteries, improving metabolism and reducing the effects of aging and inflammation.
💡Relationship between light and high energy demanding systems of the human body
🔋Mitochondria as a light-sensitive battery
🚨Red light penetration just how far does it go through the body?
🏥Application outside the lab - could changing the light bulbs in hospital reduce bed occupancy?
❤️🩹Wound healing with red light
〰️Red light vs near infra red light - it’s all about the wave lengths.
Glen - “I’ve told everyone in the lab we’ve got to stop doing science and we need to start talking” - people need this information.
Where to find Glen:
UCL Website
Mentioned in this episode:
Study - Light stimulation of mitochondria reduces blood glucose levels
Study - NASA Research Illuminates Medical Uses of Light
Book - Power Sex and Suicide by Nick Lane
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We all have that tendency to go against our own better judgement when it comes to making decisions for our health - but why do we do it when we know there’s a better option there for us? The frustration it incurs! Not to mention the time wasted… and the guilt. It most certainly isn’t a lack of information available on how to be happy and healthy - that’s abundant. So, why is it that we often don’t actually do the things we know we should?
We ask this and more with psychologist and coach, Dr Karen Doll. Karen practices what she preaches in supporting high performers with tools for psychological fitness. She asks the million dollar question - is it possible to be challenged, strive, achieve and grow without unnecessary anxiety and distress? Karen believes it absolutely is. The key? We have to be intentional about it.
We dive into:
⚖️ Sweet spot of energy and vitality without unnecessary anxiety and distress
💗 You’re never the only one struggling
🌎 “Not Enough” - a universal of human experience
🎯Why we self-sabotage and challenging core beliefs
💼📊Comparison, workaholism and successism - external to internal acceptance
📱Smart phones for psychological fitness - generative or destructive?
A big thought point for us was the following question and we’d love for you to explore it too and see how it applies in your own life. If we don’t know ourselves or what we want to be different, how will we even start the process of change?
Find Karen:
Website
LinkedIn
Harvard University Flourishing at Work Network
Mentioned:
Book - Building Psychological Fitness by Karen Doll
Book - The Anxious Generation by Jonathan Haidt
Roulette - Addiction by Design by Natasha Dow Schull
Book The Good Life by Robert Waldinger
Book Fallen Leaves by Will Durant
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Thomas Seager joins us again for a conversation challenging the conventional understanding of cancer. Thomas argues that the war on cancer, launched over 50 years ago, has failed to make significant strides in combatting the disease due to a fundamental misunderstanding of its origins.
With scientific clarity, Dr. Seager explains:
🔬the theory of cancer as a metabolic disease, beginning with defects in mitochondrial DNA, rather than the previously believed nuclear DNA
🍯 how glucose metabolism plays a crucial role in cancer growth
💧 ketosis and cold exposure therapies in inhibiting tumour growth
🏆 inspiring case studies using cold water to combat cancer (see episode with Dean Hall)
⚠️ the limitations of traditional cancer treatments (chemotherapy and radiation) and the need for more research and openness towards alternative and/or adjunct therapies focused on metabolic health, mitochondrial function, and lifestyle choices.
If you know of someone with cancer at the moment, share this with them. Or better yet, read the papers and books mentioned below and entertain the possibility that there may be additional things you can do to revolutionise their cancer care and improve the prognosis for a loved one. Surely that's worth a read.
Find Thomas:
Substack
Twitter & Instagram: @seagertp
Email
Mentioned in this episode:
Book: Uncommon Cold by Thomas Seager
Ice Bath and Cancer Science
Study - Cancer as a metabolic disease: implications for novel therapeutics
Study - Can the Mitochondrial Metabolic Theory Explain Better the Origin and Management of Cancer than Can the Somatic Mutation Theory?
Book - Cancer As A Metabolic Disease by Thomas Seyfried
Study - Brown-fat-mediated tumour suppression by cold-altered global metabolism
DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale
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