Afleveringen
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Today were covering more volatiles, thinking a bit more about the defining characteristics of volatiles and exploring MAC, Minimum alveolar concentration.
MAC, Minimum Alveolar Concentration, Ed50, Blood gas partition coefficient, Oil:gas partition coefficient, Partial Pressure, Mac-AWAKE, Mac-BAR
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The whirlwind that is enzyme kinetics in the human body for the FRCA primary exam, Enjoy!
MICHAELIS MENTEN – MASS ACTION – ENZYME KINETICS - FIRST ORDER - ZERO ORDER - ALLOSTERIC - VMAX - KM
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Zijn er afleveringen die ontbreken?
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Frca Primary Podcast looking at the properties of Atracurium, further introduction to the action of neuromuscular blocking agents and that all important exam structure!
Enjoy!
ATRACURIUM, LAUDANOSINE, HOFFMAN ELIMINATION, FRCA, FRCA PRIMARY, CIS-ATRACURIUM, BENZYLISOQUINOLINIUM
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Talking Thiopentone, the bits needed for the exam and the practical bits of when it might get used (rarely, unless the boss happen to be from the 1960's)
Enjoy!
THIOPENTONE, BARBITUATES, TAUTOMERISM, TAUTOMER, PKA, HALFLIFE, PORPHYRIA
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This is a slightly long podcast exploring how volatile anaesthetics behave and effect patients.
Chiefly thinking about how the compartments in a breathing circuit and patient interplay to achieve depth / maintain anaesthetic depth and emerge from anesthesia.
Absolutely worth a listen to get your head around compartments and also starting thinking about blood gas and oil gas partition coefficients
VOLATILE AGENTS, SEVOFLURANE, ANAESTHETIC GASES, SATURATED VAPOUR PRESSURE, BOILING POINT, BLOOD GAS PARTITION CO-EFFICIENT.
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Episode introducing clearance and then descending into bedlam trying to think about how the liver really clears drugs on a kinetics level.
I am not making you run for the hills by talking phase 1 and 2 metabolism CYP and all that jazz, that's later.
Clearance, First order, Zero order, Kinetics, FRCA, Primary, Anaesthetics, Fun
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pKa is a concept which is critical to how drugs cross membranes to their respective active sites.
pKa, Association and disassociation coefficient, pharmacokinetics,
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Volume of distribution is a pharmacological concept used as an introduction to compartmentalising humans into a variety of volumes in order to think about how drugs (or chemicals, or really anything even water....) distributes around a human.
VOD volume of distribution, pharmacokinetics, FRCA, Primary, Anaesthetics
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FRCA Primary Podcast
Were talking the core fentanyl waffle, a jump into the opiate GPCRs Receptors
And closing up with some talk on using fentanyl in day to day practice and a brief introduction to pKa
FRCA Primary Anaesthetics, Fentanyl, PKA, VOD, CYP2EI, norfentanyl
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FRCA Primary Podcast -
Were talking the core propofol waffle, what PKa is and how to think of it, and a bit about how to apply propofol to day to day work.
Propofol FRCA Primary Anaesthetics PKa 2,6 di-isopropylphenol
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FRCA Primary content
Rocuronium - neuromuscular blockade
Model answer
Dive into some of the concept
Clinical realities of its use.
