Afleveringen
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Identity Crisis | Adulteration In The Supplement IndustryIn this new episode, Emiel u/Pretty-Chill and Erika welcome Ellie, Nootropics Depot’s new Science Director. Emiel, Ellie, and Erika discuss why it's essential to lab test supplements for identity and purity, and what this means for consumers.There are way too many products on the market that don’t contain the ingredients they claim to, and this is a serious problem. In this podcast, you’ll learn about how identity testing works, why Nootropics Depot is so passionate about quality, and why Ellie is thrilled to be a part of our lab and marketing team at Nootropics Depot! Happy listening!Chapters00:00 Introduction
1:39 Benefits of Stacking Mushroom Magic Matcha & Cognance
12:00 Botanical Origin Story
17:13 Identity Testing - Watercress
27:00 HPLC Plates for Identity Testing
31:40 Testing for Erinacine A
36:00 Science Communication
50:46 Reference Standards for Erinacine A
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RELIEVEX | A Vendetta Against PainThis month’s podcast is all about pain - and our new pain management stack, Relievex!Buy Relievex from Nootropics Depothttps://nootropicsdepot.com/relievex-capsules/We at Nootropics Depot have a vendetta against pain, and Relievex is our secret weapon that provides physical and mental relief from pain. In this podcast, product specialist Emiel and podcast host Erika discuss the question “What is pain?” and what we can do to address it. Naturally, we discuss why taking Relievex is a great way to manage pain as needed, or on a daily basis.
Chapters
0:00 Introduction1:05 Taking a Full Dose of Relievex - what are the benefits?5:48 Why take Relievex? Inspiration behind the product10:26 The difference between perception of pain vs. healing the source16:04 Discussing the source of Pain (injury, inflammation, stress, lack of sleep)20:08 Breaking Down the Ingredients of Relievex22:49 Ingredients & Effects - Kava26:41 Ingredients & Effects - Lemon Balm27:54 Ingredients & Effects - Maca33:32 Ingredients & Effects - Tetrahydromagnolol35:25 Ingredients & Effects - Palmitoylethanolomide38:05 Ingredients & Effects - Supercritical Boswelia40:22 Ingredients & Effects - Ginger
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Zijn er afleveringen die ontbreken?
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Episode #37 of In Search of Insight is an in-depth conversation about hydration, electrolytes, and our new electrolyte powder, InfiniLyte. Emiel and Erika discuss why electrolytes are essential for athletes, when to take your electrolyte for the best hydration benefits, and which electrolytes are included in our unique formulation for Infinilyte.
The podcast begins by covering the basics of hydration, including how much water and minerals we actually lose during exercise. We continue with discussing the specific minerals involved in transmitting electricity in the body, the electrolytes. Emiel breaks down each ingredient in the InfiniLyte formula, and what role this plays in our body’s cellular systems.
Chapters
0:00 Introduction
3:00 Dosing InfiniLyte
12:50 How Does Hydration Work?
22:00 What Is Osmolerity - Why Do We Have It?
28:09 Electrolytes transmit electricity - Don’t Try This at Home
43:40 How Much Water and Electrolyte Should I Drink Per Day?
44:15 Ingredients of InfiniLyte
58:00 The Sensation of Hydration
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NEW PRODUCTS! InfiniLyte & BerbeLean
Learn about Nootropics Depot's new fitness supplements, InfiniLYTE and BerbeLEAN in this video! Our product specialist Emiel and In Search of Insight podcast host Erika break down the benefits, ingredients, and inspiration behind our two newest supplements.
00:00 Introduction
00:27 InfiniLyte - Comprehensive Electrolyte
42:20 BerbeLean - Berberine Stack
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From Stardust to Soil: How Cosmic Origins Enriched Us with MAGNESIUMThis podcast is all about Magnesium, and why everyone should include a Magnesium supplement in their daily stack. Nowadays, due to water and soil quality, we don’t get enough Magnesium from our diet, which can result in more stress, physical tension, gastrointestinal issues and sleep issues. In this podcast, Emiel and Erika discuss where magnesium comes from, the biological processes that require magnesium, and why Magnesium supplements are complexed with other compounds. Buy Magnesium from Nootropics Depothttps://nootropicsdepot.com/mineral-supplements/Magnesium Status and Stress: The Vicious Circle Concept Revisited Studyhttps://www.mdpi.com/2072-6643/12/12/3672#B42-nutrients-12-03672Nootropics Depot carries a variety of different forms of Magnesium, which means that you can choose the best complex for your health needs. Are you seeking a mood-boost, physical relaxation, sleep benefits, or a cognitive edge in your everyday life? Listen to this podcast to learn about Magnesium complexes, and how to determine which one is right for you. Podcast Chapters00:00 Introduction - Magnesium Supplementation1:29 Dosing Tauromag, Magnesium Pidolate, Magnesium Glycerophosphate powder8:00 Where Magnesium Comes From10:50 Elemental Magnesium17:50 Why We Should Suppement Magnesium26:25 Magnesium Complexes31:30 Neutral Magnesium forms41:30 Nootropic Magnesium forms57:00 Conclusion
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Video Episode | BERBERINE | Live Leaner, Happier, Longer
This podcast episode is about Berberine, the most effective supplement for weight loss and body recomposition. In this new episode you’ll learn how Berberine supports glucose metabolism, gut health, and our daily energy levels!Try Berberine from Nootropics Depot!https://nootropicsdepot.com/berberine-hcl-silymarin-tablets/https://nootropicsdepot.com/berberine-phytosome-capsules-550mg/Chapters0:00 Introduction - Berberine Helps Manage Glucose Metabolism3:00 Glucose Metabolism5:20 Visceral Adipose Tissue & Testosterone7:20 Berberine + Silymarin versus Berbevis (Berberine Phytosome)8:45 Dosing Berberine + Silymarin After a Light Lunch10:30 Sigma 1 - Stimulation and Energy Benefits from Berberine12:50 Dosing Berberine + Silymarin versus Berberine Phytosome13:45 GLP1 and Hunger Satiety18:26 How does GLP1 Work?19:22 How Berberine Supports Healthy Bacteria - Akkermansia muciniphila 20:25 Bioavailability Concerns - Berberine Silymarin vs. Berberine Phytosome32:25 Berberine and Curcumin as Biofilm Disruptors37:49 Berberine & AMPK Activation45:58 Why Berberine vs. C3G or Black Ginger?53:11 Mind + Body Connection - Gut Health + Mood56:02 AMPK Activation + Mood58:45 Berberine’s Effects on Neurotransmitters
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NEW PRODUCTS! ReDaxin, DHEA, TauroMag, Magnesium Pidolate, Magnesium Glycerophosphate
Chapters0:00 Introduction
1:42 TauroMag - Sleep Benefits, Relaxation, Mood
11:41 Magnesium Pidolate - Nootropic
14:00 Magnesium Glycerophosphate - Fitness
19:25 DHEA - Hormone precursor
24:26 ReDaxin - Recovery, oxidation and inflammation support
45:30 Recap
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Video Episode | BLACK GINGER | Bigger, Harder, Happier
A new podcast episode from In Search of Insight is here! This podcast episode is about our new Black Ginger extract. Black Ginger is a game-changing supplement for burning fat, achieving your fitness goals, boosting libido and sexual performance, increasing motivation and lifting mood.In this podcast, Product Specialist Emiel and podcast host Erika discuss the science behind Black Ginger’s fat-burning and libido-boosting qualities. We explain key mechanisms for Black Ginger’s benefits including thermogenesis, body recomposition, and the role of brown fat cells. We also explore the sexual function benefits of Black Ginger, namely its PDE5 inhibition which increases blood flow, which allows for better erections and arousal. Adding to these benefits, Black Ginger has a unique method of lifting our mood and motivation through it’s modulation of neurotransmitter release and processing. Buy Black Ginger from Nootropics Depothttps://nootropicsdepot.com/black-ginger-extract-capsules/Podcast Chapters
0:00 Introduction + Double Dose of Black Ginger
4:34 Black Ginger Benefits
5:00 Fitness + Endurance Benefits of Black Ginger
10:47 Fat Burning + Body Recomposition Benefits
19:21 Muscle Protein Synthesis Pathways
23:11 Sitruin 1 Activation
28:45 Summary of Fitness Benefits + Pathways
30:30 Sexual Function + Libido Benefits
31:59 PDE5 Inhibition
39:25 Neurotransmitter Release Process
43:42 Summary of Libido Benefits
49:12 Perceptible Benefits of Black Ginger
53:15 Stacking Black Ginger
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Mr. Happy | The Next Generation - Part 2
Tune into the second half of our fascinating conversation with Joshua, A.K.A. Mr. Happy from the famous Mr. Happy Stack. We discuss more insight on how the microbiome, immune system, hormones and neurotransmitters are connected. These systems rely on us to exercise, to eat well, and to be able to recover. However, our lifestyle, food supply, and other factors can make it difficult to maintain a healthy baseline. And further, how do supplements play a part in all of this?
Part 2 of the podcast is an activating deep-dive that motivates us to take our health seriously, and better understand the main factors that allow us to live long, healthy and happy lives. These are the immune system, the microbiome, the hormone biosynthesis system, and our diets.
Click to Learn More About Joshua's Immune System Research
https://bornfree.life/understanding-the-model/6/updated-disease-model-wip/45/
1:20 In Vivo vs. In Vitro
5:20 The Importance of the Micro-Biome
14:55 Mineral Deficiencies
18:00 Dietary Minerals
23:30 Bio-films and the Immune System
28:00 Dopamine Synthesis and Nootropics
35:00 Hormone Biosynthesis
42:00 Testing Our Microbiome + Bacterias
44:40 Getting to the Root of Hormonal Imbalance
47:00 Are Male Testosterone Levels Dropping?
50:00 NADH Supplementation
56:00 The Importance of Exercise
57:00 The Importance of Libido
1:03:00 Which Tests Work Best for Microbiome
1:05:30 Understanding Our Microbiome
1:11:00 Conclusion
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Mr. Happy | The Next Generation
1:27 Longecity Forum - Early Nootropics Community
3:20 Foundations of Supplement Experimentation
7:50 Shifting Towards Minerals and Micronutrients
15:30 Origins of Nootropics Depot + Our Purity Standards
18:31 Vendors and Sourcing
26:30 Lion’s Mane, Reishi, Mushroom Research
28:20 Cultivating Lion’s Mane
35:50 Reishi + Immune Response
39:40 Joshua’s Immune System Research - Biofilms
51:05 Future of Accessible Research Studies
55:00 Citizen Scientists
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CistaMAX | The Road To The Perfect CistancheThis month on the In Search of Insight podcast, Emiel and Erika share the inspiration behind Nootropics Depot’s new CistaMAX stack! We combined non-extracted Cistanche, a high-potency Cistanche extract, and a Supercritical Cistanche extract with Shilajit, Pregnenolone and DHEA to create CistaMAX. This combination produces a noticeable stimulating and motivating effect, and boosts the muscle-building properties of Cistanche. In this podcast, you’ll learn why we chose each ingredient in CistaMAX and what purpose it serves in the stack as a whole. You’ll also learn about the neuroscience behind the focus and mood enhancing effect of Cistanche. There’s lots of reasons why we include CistaMAX in our daily stack - it can increase feelings of hunger, which is essential when bulking and building muscle. It also gives us a noticeable energy boost that makes us want to move more. CistaMAX is a great choice for supporting fitness, motivation, and hormonal balance. Listen to our new episode to learn more!Buy CistaMAX from Nootropics Depothttps://nootropicsdepot.com/cistamax-capsules/Follow Us on Social Mediahttps://www.reddit.com/r/NootropicsDepot/https://www.instagram.com/nootropicsdepot/https://www.facebook.com/NootropicsDepot/https://www.instagram.com/insearchofinsight?igsh=MTVtdDB1d2ZpZm9sbA%3D%3D&utm_source=qrPodcast Chapters00:00 Introduction00:32 Exploring the elements of CistaMAX3:46 What is the best dose for CistaMAX?7:53 Hunger-boosting effects of CistaMAX15:52 Steroidogenesis - androgenic benefits of CistaMAX20:24 Gut-health benefits of Cistanche26:51 Echinacoside and Acetoside - active compounds32:14 Perceptible benefits of CistaMAX32:40 CistaMAX and glucose absorption40:22 Developing the CistaMAX stack51:03 Pregnenolone, DHEA, and Shilajit in CistaMAX55:29 Motivation, energy, and mood boost 1:01:51 How to determine what is and isn’t working in your stack1:04:55 Does CistaMAX benefit workout recovery?1:11:05 Conclusion
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Tribugen | How We Took Tribulus To The Next LevelThis month, Emiel and Erika discuss the benefits of Tribulus Terrestris for energy, motivation, focus, and hormonal health. Making an effective stack takes more than just scientific research - this podcast episode focuses on the human element of stack creation, and why we spent so much time refining Tribugen until we got the effects profile just right.On this month’s podcast, learn more about:Tribulus Terrestris, Fenugreek, Dioscorea nipponica, and CordycepsMonoamine oxidase A and B inhibitorsMegadosing TribugenHow Nootropics Depot creates synergistic stacksEach ingredient in Tribugen was selected to compliment the stimulating and motivating effects of Tribulus, and in this episode Emiel discusses the mechanisms of action that are responsible for these effects. Before Tribugen made it’s debut, the team at Nootropics Depot tried a variety of Tribulus Terrestris extracts to find the most motivating but smooth extract that would shine as a stand-alone product. When making Tribugen, we wanted to increase the motivation benefits of Tribulus, but to smooth out the stimulation and edginess of Tribulus when taken on its own. After a year of bioassaying Tribugen, adjusting the dosages of the synergistic ingredients, and sharing the pre-released stack with friends, family and colleagues, we arrived at the finished product. If you are interested in learning more about this process, and the ingredients that make up the Tribugen stack, tune into this podcast episode! Podcast Chapters0:00 Introduction3:06 Mega-Dosing Tribugen6:07 Making A Next-Level Tribulus Terrestris Extract8:45 Why Do People Reach for Tribulus?17:00 Where Do We Source Our Tribulus Terrestris?18:40 β-carbolines - Monoamine Oxidase Inhibitors21:00 Connecting Pharmacodynamics with Perceptible Benefits24:00 Creating the Tribugen Stack32:00 Taking Tribulus with Vignatex34:00 How Cordyceps Interacts Within the Tribugen Stack35:29 Cordyceps + Caffeine Connection40:30 Choosing Synergistic Compounds + Dosages58:30 Protodioscin + Diosgenin1:05:19 DHEA 1:08:00 Focus Enhancing Effects of Tribugen1:09:00 Stimulation Effects of Tribugen1:21:00 Conclusion
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March Mushroom Magic | Energy, Focus and Motivation From Your Daily Dose of Adaptogenic Mushrooms
Have you experienced the mood lifting, physically relaxing, cognition enhancing benefits of adaptogenic mushrooms? Listen to our new podcast episode as we review Nootropics Depot's new Mushroom Magic drink mixes! Emiel and Erika disucss how Nootropics Depot sources coffee, matcha and cocoa for the most delicious drinking experience, and why Mushroom Magic drinks are great to share with friends and family! Learn more about why we chose Lions Mane, Cordyceps, Tiger Milk and Poria mushroom for our blend of gut health boosting, energizing, and immune supporting drink mixes.
Are you interested in making adaptogenic mushrooms a part of your everyday supplement stack? Mushroom Magic drink mixes are the easiest and tastiest way to get full servings of four highly-effective, non-extracted mushrooms, proven for their cognition and immune health benefits. Tune into the podcast to learn more about each mushroom, and why we chose to include Lions Mane, Cordyceps, Poria and Tiger Milk in our first ever drink mix.
On this month’s podcast, learn more about:
How we make mushroom magic matcha, coffee, cocoa, and lattes at home
Why we chose Poria, Tiger Milk, Cordyceps and Lions Mane mushroom in our mixes
How mushrooms benefit our gut health, cognition, focus, and energy
Which Mushroom Magic drink mix is right for you
Buy Mushroom Magic Drinks Here
https://nootropicsdepot.com/mushroom-magic-coffee/
https://nootropicsdepot.com/mushroom-magic-matcha-latte/
https://nootropicsdepot.com/mushroom-magic-coffee-latte/
https://nootropicsdepot.com/mushroom-magic-matcha-powder-blend/
https://nootropicsdepot.com/mushroom-magic-cocoa/
Learn More About Lions Mane and Tiger Milk Mushrooms
Follow Us on Instagram
Podcast Chapters
00:00 Introduction
00:40 Introducing Mushroom Magic Drink Mixes
1:02 Gut Function and Microbiome
1:45 Beta Glucans and Polysaccharides Benefit Our Gut
3:45 Follow Us On Instagram @insearchofinsight
5:20 Poria Mushroom Sclerotium
6:25 Check Out Emiel’s Updated Stack on Reddit
8:15 Unextracted Mushrooms Contain More Beta Glucans
9:00 500 Milligrams of Poria, Lion’s Mane, Cordyceps, and 150 mg Tiger Milk
11:20 Why Mushroom Magic Drinks Contain SCOOPS
19:35 Drinking Mushroom Magic Matcha - iced latte with milk
25:20 Stevia - Why We Sourced a Higher Quality Stevia
28:00 Perceptible Effects of Mushroom Magic Matcha
31:50 Our Matcha vs. Traditional Matcha Teas
34:50 Ceremonial Grade Matcha
38:05 Effects of Poria and Tiger Milk sclerotium
49:25 Checking in On the Perceptible Benefits
56:39 The Difference Between Caffeine and Mushrooms in Isolation vs. Mushroom Magic mixes
58:05 Beta Testing Mushroom Magic drinks with friends, family and coworkers
1:07:30 Drinking Mushroom Magic Coffee
1:20:43 Non-Perceptible Benefits of Adaptogenic Mushrooms
1:26:29 Drinking Mushroom Magic Cocoa
1:39:38 Cordyceps Mushroom Health Benefits
2:08:30 Drinking Mushroom Magic Coffee Latte
2:12:40 Mushroom Magic with your Daily Supplement Stack
2:14:20 Be Moderate When Taking Multiple Doses of PreBiotics - Digestion
2:19:00 Coffee Approved By Coffee Nerds (Emiel and Erika)
2:20:30 Closing Remarks on Perceptible Benefits of Mushroom Magic Drinks
Lion’s Mane Mushroom | The Journey To Connect Modern Science With Traditional Chinese Medicine
Tiger Milk | Could It Be The New Lion's Mane? | This Rare Malaysian Mushroom Is Finally On The Prowl -
Your Body’s Amazing Immune System | Is It Better To Take A Natural Approach When You Get Sick?
Our immune system is our body’s defense against sickness and infection. In this month’s podcast episode, Emiel and Erika discuss inflammation, oxidation, immune supporting supplements, fermented foods, and gut health, and explore ways to stay healthy all year round.Tune into the new podcast episode to learn more about:How inflammation and oxidation are tools that the immune system uses to attack pathogens and help us recover from illnessWhy fermented foods and carbohydrates are essential for a healthy immune systemVitamins, minerals, and supplements that support a healthy immune systemThe connection between the gut and the immune systemWhy symptom management during illness can work against us, and what to do insteadThis episode is focused on why inflammation and oxidation are essential for helping us fight off pathogens, and therefore, why taking a natural approach when getting sick may help us recover faster. Sometimes, it can be advantageous to lean into the inflammation and oxidation caused by our immune system, though this can be uncomfortable. Dampening inflammation and oxidation can prolong illness, and work against our immune system’s natural response to pathogens.Follow In Search of Insight on Instagramhttps://www.instagram.com/insearchofinsight?igsh=ZGNjOWZkYTE3MQ%3D%3D&utm_source=qrBuy Immune Supporting Supplements from Nootropics DepotInfini Chttps://nootropicsdepot.com/infini-c-capsules/Vitamin Dhttps://nootropicsdepot.com/vitamin-d3-k2-with-vitamin-c-tablets/https://nootropicsdepot.com/vitamin-d3-k2-c-supplement/Vitamin Bhttps://nootropicsdepot.com/infini-b-capsules/Zinchttps://nootropicsdepot.com/microzinc-capsules-zinc-supplement/N-Acetyl Cysteinehttps://nootropicsdepot.com/n-acetyl-l-cysteine-500mg-capsules/Micromag https://nootropicsdepot.com/micromag-capsules-optimized-magnesium/Andrographis paniculatahttps://nootropicsdepot.com/andrographis-paniculata-capsules-50-andrographolides/Reduced Glutathionehttps://nootropicsdepot.com/reduced-glutathione-tablets/Recommended Podcasts on the Immune SystemUsing Your Nervous System to Enhance Your Immune System - Huberman Labs Podcasthttps://www.youtube.com/watch?v=poOf8b2WE2g&t=3604sThe Ultimate Cold Prevention Protocol: Strengthening The Immune System with Chris Masterjohnhttps://www.youtube.com/watch?v=ygeJSE2Xz4w&t=3510sPodcast Chapters00:00 Introduction - Immune System01:15 How Does Our Environment Affect Our Immune System?05:30 Inflammation and Oxidation are Tools of the Immune System06:45 Taking GABA for Immune Function17:20 The Impact of Gut Health on the Immune System - Why Kombucha?18:50 How Lindsay Lohan Ruined The Kombucha Industry23:40 Stomach Acid is the First Line of Defence Against Viruses and Bacteria26:44 How Fermentation and Food Preservation Supports Our Immune Function30:44 Sauerkraut - Low PH Means Bad Bacteria Die, Good Bacteria Live36:25 Short Chain Fatty Acids - Fibers, prebiotics, and biotics42:45 How the Immune System Functions Beyond Our Gut46:05 We Have Microbiomes Everywhere47:55 Innate vs. Adaptive Immune System57:30 How Genetics Factor Into Our Immune System Response1:00:00 Leaning Into the Immune Response1:09:43 Why Do We Get Fevers When We Get Sick?1:30:16 Sickness Behavior1:34:34 How To Boost Immune System When You’re Not Sick1:54:00 Behavior, Micronutrients, and Mushrooms2:14:00 How to Take Supplements When Getting Sick2:18:47 Supplements to Support Your Immune System2:33:39 GABA for the Gut, Mood, and Immune System2:36:14 Conclusion
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Video Episode | Kanna | Can This South African Succulent Make You a Better Dancer?
Kanna is a unique succulent plant, originating from South Africa. It has been used as a mood and energy boosting botanical for thousands of years by the KhoiSan people of South Africa, for dancing ceremonies and as a hunting aid.
In this month's podcast episode, Emiel (Nootropics Depot Product Specialist) and Erika discuss the history of Kanna, its pharmacokinetics and mechanisms of action, and how Kanna provides a distinctly uplifting effect from its serotonergic activity.
Tune in to learn about dosing Kanna, taking Kanna at night clubs in Amsterdam, mesembrine, mesembrenone, and Delta 7 mesembrenone, and why you should try Kanna for its pro-social benefits. Follow In Search of Insight on Instagramhttps://www.instagram.com/insearchofinsight?igsh=ZGNjOWZkYTE3MQ%3D%3D&utm_source=qrBuy Full Spectrum Kanna Tablets from Nootropics Depothttps://nootropicsdepot.com/full-spectrum-kanna-extract-quick-dissolve-tablets/Read Nootropics Depot's Blog on Kannahttps://nootropicsdepot.com/kanna-lift-mood-and-lower-stressPodcast Chapters 00:00 Introduction04:10 Dosing Kanna09:40 Stimulating Effects of Kanna11:50 Fat or Water Soluble? Bioavailbility of Kanna17:30 Oral & Sublingual Administration18:53 Pharmacokinetics - T Max and C Max 34:00 Caffeine Usage and Concentration36:00 Dynamax Pharmicokinetics38:45 Mood, Focus, Energizing, Pro-Social Effects of Kanna43:00 Traditional Uses of Kanna, Amanita Muscaria, Kava50:00 Neuroscience of Kanna - Neurotransmitter Releaser53:07 Mesembrine acts as a VMAT2 Upregulator1:03:40 Testing Mesembrine Content of Kanna Extracts1:14:10 Cultivars of Kanna - Sceletium tortuosum1:14:54 What Sets Nootropics Depot’s Kanna Extract Apart1:18:22 Beta Testing and Initial Bio-assaying1:25:31 Kanna as a Subtle Appetite Suppresant1:33:11 Emiel & Erika’s Current Occasional Supplements1:47:07 Emiel & Erika’s Daily Supplement Stack1:57:24 Conclusion
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Isoliquiritigenin | Candy For Your Brain
This month, learn all about neurotransmitters and the powerful mechanisms of action behind Nootropics Depot’s mood-boosting licorice root extract, Isoliquiritigenin. Erika and Emiel take you on a journey through the traditional uses of licorice, what makes it such a soothing remedy for inflammation, and where licorice candy originates from.
Buy Isoliquiritigenin from Nootropics Depot
https://nootropicsdepot.com/isoliquiritigenin-controlled-dissolve-tablets/
Follow In Search of Insight on Instagram
https://instagram.com/insearchofinsight?igshid=MzMyNGUyNmU2YQ%3D%3D&utm_source=qr
Podcast Chapters
00:00 Introduction
00:18 Licorice Root
03:53 Isoliquiritigenin
06:07 Mega-Dosing Isoliquiritigenin
10:27 Traditional Uses of Licorice Root
14:23 Why Is Licorice Candy Black?
15:28 Where The Classic Licorice Flavor Came From
24:32 Slight Detour - The Use of Quinine in Tonic Water
28:58 The Medicinal Background of Vermouth, Absinthe, Coca Cola
32:00 Tasting Dutch Licorice
35:12 Ammonium Chloride as a Cough and Mucus Remedy
43:00 Laws Against Licorice
44:54 Tasting Mild Salt Licorice
48:02 Benefits of Licorice Root and Isoliquiritigenin
54:12 The Pharmacology of Isoliquiritigenin
57:36 Neurotransmitter Basics
1:00:38 What Effects are Produced When Norepinephrine, Serotonin, and Dopamine Build Up?
1:02:34 GABA-A and GABA-B Activation
1:06:20 GABA, Amino Acid Neurotransmitter vs. Norepinephrine, Serotonin, and Dopamine Monoamine Neurotransmitter
1:08:19 Why We Typically Try to Dampen Glutamatergic Activity
1:09:40 Glycine, a Neurotransmitter
1:16:17 Dopamine D3 Agonist Effects of Isoliquiritigenin
1:18:38 Isoliquiritigenin For Pain Management
1:20:21 Isoliquiritigenin For Long Term Potentiation
1:22:47 Tonic Water - Traditional and Modern Uses
1:26:32 New Products From Nootropics Depot - Mushroom Magic Matcha
1:31:57 Why Not Ceremonial Grade Matcha?
1:36:55 The Mushroom Blend of Mushroom Magic Matcha
1:46:08 The First Scoop for Nootropics Depot
1:48:48 Full Spectrum Kanna Tablets
1:55:21 Taking Kanna at the Club
1:57:27 Conclusion
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An Unexpected Journey Through The Past & Future Of Supplements With Lucas Of Boost Your Biology
This month on In Search of Insight, we welcome Lucas Aoun from Boost Your Biology and embark on an unexpected, stimulating journey through the past and future of supplements.
Learn More About Lucas Aoun of Boost Your Biology https://www.youtube.com/@UC4O8s5Eir3A0ULQ-0HOJr8Q https://www.youtube.com/@UCG-Da6bw7vNJ4oEkhs-D_KQ
Meet Lucas and learn about his background as a biohacker, Naturopath, and supplement enthusiast. In this episode, Emiel, Lucas, and Erika share the beginnings of their journeys with supplements. They discuss what products they’ve loved and hated, new frontiers in the supplement world, and why quality and safety are the most essential elements in supplementation.
Podcast Chapters
0:00 Introduction
1:15 Beta Testing Unreleased Cistanche Stack + Tribugen
5:00 Meet Lucas Aoun
6:45 Extraction Technique for Cognance - Producing a Non-Drowsy Bacopa Extract 14:00 Glycosides in Botanicals
17:21 Extraction Techniques of Cognance, Erinamax
21:47 Lucas’ Journey in Nootropics Begins
23:28 Acetyl L-Carnitine, an Early Adopted Nootropic
26:33 Emiel’s Journey in Nootropics Begins
28:41 Bioassaying Tribugen
31:59 Pre-Workout Formulations
34:15 Ginkgo Biloba
38:31 Clinical Trials vs. Empirical Evidence
39:49 Approaches to Research
42:18 Asking Questions, Asking the Right Questions
46:18 How Reddit Inspired Nootropics Depot 49:08 Benefits of Community Bioassaying
51:41 Staying Close to the Source When Researching
56:19 When Research Studies Can’t be Verified
59:02 The Origins of Acetylcholinesterase inhibitors
1:01:25 Plant Defence Systems
1:04:38 Beta Ecdysterone
1:06:39 Being Critical of Research
1:09:34 Erika’s Journey with Nootropics Begins
1:14:34 Safety Concerns of Fadogia Agrestis
1:17:21 Fadogia Agrestis Toxicology
1:20:45 The Future of Nootropic Supplements from Africa
1:21:20 Kanna and its Traditional Uses
1:38:00 Naturopathy and Nootropics
1:40:00 Criteria for Nootropics - Gurgia
1:47:40 How Traditional Chinese Medicine Informs Modern Nootropics
1:51:00 Shizandra Chinensis
1:52:20 Eria Jarensis
1:54:40 Dynamine
2:02:16 The Benefits of Progesterone
2:08:25 Enhancing Insulin Sensitivity
2:09:20 Conclusion
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Megadosing And DNA Testing w/ Joe Cohen | Why The Founder Of SelfDecode Takes 150 Supplements A Day
This month we welcome our featured guest, Joe Cohen of SelfDecode to the In Search of Insight Podcast. Joe’s passion for quality supplements, enthusiasm for sharing his knowledge, and commitment to lab testing is unmatched in the industry. Learn about SelfDecode, the ways that genetic testing and supplement testing work together, and how Joe Cohen tests new supplements with mega dosing. Tune into this month’s podcast episode to learn about:
Why Joe Cohen takes 150+ supplements every day
What sets SelfDecode apart from other supplement recommendation tools
Megadosing Nootropics Depot supplements
How Joe boosts his testosterone, supports thyroid function, and monitors health risks through supplementation and frequent blood tests
Joe’s favorite Nootropics Depot supplements
Joe's 150+ Supplement Regimen
My Regimen of 150 Supplements
https://selfhack.com/blog/joes-personal-health-regimen/
My Regimen of 150 Supplements (Detailed)
https://selfhack.com/blog/my-regimen-of-150-supplements-why-i-take-them/
Podcast Chapters
0:00 Introduction
2:22 Why Joe Cohen Mega Doses Supplements
10:00 Megadosing Cognance
18:37 Supplements with Anti-Thyroid function
22:56 Introducing SelfDecode
31:17 Biggest Mistakes in Genetic Testing
39:52 Optimizing Your Biology
43:36 Joe Cohen’s 150+ Supplement Stack
45:49 Mood, Cardiovascular Health, Kidney Health, Thyroid Function
54:44 The Benefits of Frequent Lab Testing
58:46 Why Supplement Lab Tests and Blood Lab Tests Are Important
1:03:48 Breaking Down Joe’s Supplement Stack
1:08:14 Supplements to Support Food Tolerance
1:12:26 The Difference Between SelfDecode and Other Supplement Advice Tools
1:20:49 Checking In on the Cognance Megadose
1:21:19 How Bacosides Effect Thyroid Hormone
1:26:22 Necessity for Data in Supplementation
1:29:24 Joe’s Testosterone Benefits from Tongkat Ali
1:35:29 Clinical Trials for Supplements
1:38:20 Joe’s Favorite Nootropics Depot Supplements
1:38:20 Megadosing Sabroxy
1:50:19 The Human Element of Supplementation
1:56:45 Lab Testing and Safety of Supplements
2:02:31 Joe’s Favorite ND Supplements, Continued
2:23:51 Conclusion
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Discovering Bacopa | What’s Hiding In Plain Sight?
If you’re a part of the Nootropic supplement world, you know that Bacopa is a powerful and effective supplement for memory, sleep quality, relaxation, and mood. However, there are many fascinating mechanisms at play that have made Bacopa a well-known supplement for centuries, even in traditional Ayurvedic practices. Bacopa is more than just a supplement, commonly used as a decorative plant, growing in semi-aquatic environments in the wild, and can be found for sale in nurseries around the world. It’s time to discover the wonders of Bacopa, the Nootropic botanical that is hiding in plain sight!
Chapters
0:00 Introduction
2:50 Dosing Bacopa 24%
3:13 Our New Microphones
6:51 Line Audio CM4 Microphones
12:08 Positive vs. Negative Responses to Bacopa
13:29 Benefits of Cognance vs. Traditional Bacopa extract
16:44 Mushroom Kingdom Update
18:06 Hericium Coralloides, Hericium Abietis, Hericium Americanum, Hericium Erinaceus
19:28 The Difference Between a Cultivar and a Species
21:53 Comparing Coffee, Hemp, and Hops Cultivars
24:13 Investigating Cultivars and Species in Mushroom Kingdom
27:46 Evaluating the bioactive differences between Cultivars and Species
30:11 High Performance Thin Layer Chromatography
32:18 Image of HPTLC Plate
39:26 Mushroom Cultivation Logistics
41:35 Why We Source Mushrooms from Asia
44:02 Perceptible Effects of Bacopa 24%
52:29 Stacking Bacopa 24% with Cyanidin 3-Glucoside
54:45 Dosing Bacopa at Nighttime vs. Daytime
55:22 Why Bacopa enhances sleep quality
57:21 The Cyanidin 3-Glucoside Shortage
1:00:25 The Difference Between Synapsa, Bacognize, Bacopa 24% and Cognance
1:04:17 Bioavailability - Taking with or without a fat source
1:05:03 Bacopa is More Common Than You Think
1:07:03 Why We Adhere to Prop - 65 Heavy Metal Limits
1:07:58 From Ayurvedic Bacopa to Modern Extracts
1:11:13 Why Saponins Make Standardizing Bacopa a Challenge
1:13:20 Bacoside A
1:15:00 HPTLC Testing vs. UVVis
1:17:04 Standardization of Synapsa, Bacognize, Bacopa 24%
1:25:07 Cognance Effects vs. Traditional Bacopa Extracts and Ebelin Lactone
1:35:17 Beta-testing Cognance
1:43:55 Comparing Bacopa Extract Effects to Wine
1:47:02 Stacking Bacopa 24% with Cyanidin 3-Glucoside
1:51:42 Norepinephrine Balancing Effect of Bacopa
1:52:13 Serotonin Modulating Effect of Bacopa
1:55:23 Enhances Density of the 5-HT3A Receptor
1:56:41 Tryptophan Hydroxylase and Increasing Density of Serotonin Transporter
1:58:07 Combining Full Spectrum and Targeted Standardized Extracts
2:00:08 Bacopa as an Adaptogen
2:01:10 Bacopa and GABA
2:04:38 How Long Does it Take for Bacopa Effects to Kick In?
2:06:19 Memory Benefits of Bacopa Extracts
2:16:13 Stacking with Bacopa 24%
2:17:21 Focus, Mood and Memory Stack - Bacopa 24%, Cognance, Saffron, Sabroxy
2:20:49 Relaxation Stack - Bacopa 24%, Shoden Ashwagandha, Tetrahydromagnolol, GABA
2:22:38 Lights Out Stack - Bacopa 24%, Supercritical Coriander, Oleamide, Magnolia Bark, Tetrahydromagnolol
2:23:02 Memory Stack - Mr. Happy Stack - Bacopa 24%, OmegaTau
2:24:19 Nootropic Memory Enhancement - Bacopa 24%, OmegaTau, Cognance, Erinamax
2:25:54 Conclusion
Product Links
Cognance Capsules
https://nootropicsdepot.com/cognance-enhanced-bacopa-capsules/
Cognance Powder
https://nootropicsdepot.com/cognance-enhanced-bacopa-powder/
Bacopa 24% Capsules
https://nootropicsdepot.com/bacopa-monnieri-tablets-minimum-24-bacosides/
Bacopa 24% Powder
https://nootropicsdepot.com/bacopa-monnieri-extract-powder/
Synapsa Capsules
https://nootropicsdepot.com/synapsa-bacopa-monnieri-extract-whole-plant-320mg-capsules/
Synapsa Powder
https://nootropicsdepot.com/synapsa-bacopa-monnieri-extract-whole-plant-powder/
Bacognize Capsules
https://nootropicsdepot.com/synapsa-bacopa-monnieri-extract-whole-plant-320mg-capsules/
Bacognize Powder
https://nootropicsdepot.com/bacopa/https://www.reddit.com/r/NootropicsDepot/https://www.instagram.com/nootropicsdepot/https://www.facebook.com/NootropicsDepot/
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Lion’s Mane Mushroom | The Journey To Connect Modern Science With Traditional Chinese Medicine
Learn what sets Nootropics Depot’s Lion’s Mane Mycelium apart from the crowd in episode #22 of the In Search of Insight podcast.
This month we discuss our new Lion’s Mane mycelium product and the years of research and testing we spent creating this next-level supplement. Tune into the podcast to learn about Lion’s Mane mycelium, and listen to Erika, Emiel and Jay discuss:
The difference between fruiting body and mycelium supplements
How Lion’s Mane mycelium benefits cognitive health, nerve health, and mood
Perceptible effects of our new Lion’s Mane Mycelium
How Omnient Labs is raising the bar for standardization in the supplement industry
Buy Lion's Mane Mycelium from Nootropics Depot
https://nootropicsdepot.com/erinamax-tablets/
Buy Isoliquiritigenin from Nootropics Depot
https://nootropicsdepot.com/isoliquiritigenin-controlled-dissolve-tablets/
Podcast Chapters
0:7 Introduction
1:30 Taking Lion’s Mane Mycelium
12:01 New Product Release - Isoliquiritigenin
16:22 Sublingual Dosing
22:08 Isoliquiritigenin Video
23:50 Health Benefits of Isoliquiritigenin
30:55 Dopamine Reuptake Inhibition
39:25 Why Try Isoliquiritigenin
44:58 Noticeable Effects of Lion’s Many Mycelium
50:20 Nerve Benefits from Mycelium
53:34 Standardizing Lion’s Mane to Erinacine A
57:10 NGF + TrkA Receptor Stimulation
1:05:40 Review of Lion’s Mane Mycelium Benefits
1:12:00 Special Guest James Jursich
1:14:05 Initial Stages of Lion’s Mane Mycelium Research
1:18:41 Building Growth and Testing Methods
1:25:04 From Mycelium to Liquid Culture
1:26:51 Producing Liquid Culture at Commercial Scale
1:34:43 NMR - MRI for Molecules
1:40:39 Why Did Nootropics Depot Create a Mycelium Product?
1:46:53 Benefits of Lion’s Mane Mycelium vs. Fruiting Body
1:48:02 Developing Mushroom and Mycelium Research
1:56:49 The Risks of Contamination in Materials
2:04:43 Research for Practical Use of Mycelium
2:06:44 Jay’s New Video Series
2:10:29 Comparing Nootropics Depot’s Mycelium to Mycelium-On-Grain
2:07:30 Stacks
2:15:26 Four Mushroom Blend
2:18:52 Inflammation Support Stack
2:20:36 Inspiration Stack
2:24:44 Microdose Stack
2:25:58 Final Check-In for Perceptible Effects of Mycelium
2:30:37 Conclusion
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