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  • On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM) Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP) Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID) Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID) Use of Dolutegravir for treatment of HTLV-1 (CID) Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID) Bacterial Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID) Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA) Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID) Parasitic Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET) Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement (JAMA Network OPEN) Febrile Temperature Augents Ring-stage Plasmodium falciparum Adhesion to Brain Endothelial Cells (JID) An Increase in Imported Plasmodium vivax Malaria in New York City: Clinical and Demographic Trends Following Recent Migration (OFID) Miscellaneous The State of Physician Leadership (WittkKieffer) Infectious Diseases Fellowship Curriculum: IDSA Training Program Directors Community of Practice (TPDCOP), Curricular and Educational REsources Workgroup (CREW) (CID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #106 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/23 – 5/6/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Andes hantavirus outbreak in cruise ship, 11 May 2026(European Centre for Disease Prevention and Control) 2026 Multi-country Hantavirus Cluster Linked to Cruise Ship (CDC: Health Alert Network) "Super-Spreaders" and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) We Dissent: Lessons From the 2025 Community-Acquired Pneumonia Guidelines (CID) Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient (OFID) Impact of Respiratory Syncytial Virus Immunization on the Rate of Pediatric Acute Otitis Media: A Time-series Analysis (CID) Bacterial Performance of a rapid, visual fingerstick serology self-test for Helicobacter pylori detection and typing: A prospective multicenter diagnostic accuracy study (CMI: Clinical Microbiology and Infection) Real-world effectiveness of 20-valent pneumococcal conjugate vaccine against all-cause outcomes among Medicare beneficiaries aged 65 years and older in the USA: a retrospective cohort study (LANCET: Infectious Diseases) Beta-Lactam plus Azithromycin or Doxycycline versus Fluoroquinolones in Hospitalized Adult Patients with Community-Acquired Pneumonia: A Systematic Review and Network Meta-Analysis (OFID) Syphilis and the risk of stroke: a nationwide, population-based matched cohort study (CMI: Clinical Microbiology and Infection) Reducing Bacterial Contamination of Blood Bags with a Double Knot (NEJM) Effectiveness and safety of daptomycin versus vancomycin in methicillin-resistant Staphylococci left-side infective endocarditis. Results from a nationwide prospective multicenter cohort. (CMI: Clinical Microbiology and Infection) Fungal The Last of US Season 2 (YouTube) Non-intravenous Amphotericin B: A Review of Localized Administration Routes (Infectious Diseases and Therapy) Parasitic Duration and association with protection of NANP-repeat-specific and C-terminus-specific anti-circumsporozoite protein IgG responses following RTS,S/AS01E vaccination: an observational ancillary immunological study of a phase 3 clinical trial (LANCET: Infectious Diseases) Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies (NEJM) Miscellaneous Interest in Infectious Diseases Among Internal Medicine Resident Physicians: Results From a Nationwide Survey (CID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

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  • On episode #105 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/9 – 4/22/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients (NEJM) Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir (NEJM) Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP) Risk of Guillain–Barré Syndrome after Laboratory-Confirmed Dengue Infection (NEJM) A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage (JID) First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID) Bacterial Tetanus Surveillance — United States, 2009–2023 (CDC: MMWR) Notes from the Field: Tetanus in Four Children — Idaho, Minnesota, Missouri, and Wisconsin, 2024 (CDC: MMWR) Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults (JAMA) Efficacy and safety of vancomycin versus 13 alternatives in MRSA-confirmed skin and soft tissue infections: a meta-analysis of 39 randomized controlled trials (Infection) Methicillin-Resistant Staph Aureus (MRSA) Nasal Swab Utilization as a Predictor for MRSA Skin & Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID) Practice variation, outcomes and definitions of suppressive antimicrobial therapy for prosthetic joint infections: a systematic review and expert consensus statement (CIC) Efficacy and safety of VPM1002 and Immuvacin preventing tuberculosis: phase 3 randomised clinical trial (PreVenTB trial) (BMJ) Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis (CID) Do C-Reactive Protein Measurements Predict Treatment Failure in Native Vertebral Osteomyelitis? (OFID) Fungal The Last of US Season 2 (YouTube) Rising burden of severe pediatric coccidioidomycosis: a 25-year single-center study (Journal of the Pediatric Infectious Diseases Society) Candida glabrata emerges as the most common cause of candidemia: analysis of a large hospital-based database, United States, 2016–2024 (CID) Test Performance and Clinical Utility of the cobas® eplex Blood Culture Identification Fungal Pathogen Panel (OFID) Cutaneous Paraconiothyrium cyclothyrioides Infection in Lung Transplant Recipient, Georgia, USA (Emerging Infectious Diseases) Azole Resistance in Aspergillus fumigatus From Diverse Environments in Ohio, United States, Is Primarily Driven by TR34/L98H and TR46/Y121F/T289A Environmental Signatures (OFID) Parasitic Fatal Donor-Derived Disseminated Acanthamoeba Infection in a Liver Transplant Recipient (OFID) Miscellaneous Host–microbiome archetypes differentiate infection from pathogen carriage in the human lower airway (Nature Communications)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #104 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/26 – 4/8/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis (Neurology) Bacterial Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study (CID) Inhaled Antibiotics to Treat Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis (Critical Care Medicine) ATS/IDSA 2016 Clinical Practice Guidelines for the Management of Adults With Hospital-Acquired and Ventilator-Associated Pneumonia (ISDA) Risk of Invasive Meningococcal Disease in Children Aged
  • On episode #103 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/12 – 3/25/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Probable Japanese Encephalitis Virus Transmission through Organ Transplantation (NEJM) Clinical Characteristics and Severity of Rhinovirus/Enterovirus–Associated Hospitalizations: A Multi-country Analysis from the Global Influenza Hospital Surveillance Network, 2017–2024 (OFID) Bacterial Eagle effect (Wikipedia) THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS (JEM) Linezolid versus clindamycin for toxin inhibition in severe skin and soft tissue infections: a systematic review and meta-analysis (Infection) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (Critical Care Medicine) Caring for Adult Patients With Sepsis (JAMA) Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Intensive Care Medicine) Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Pediatric Critical Care Medicine) Caring for Pediatric Patients With Sepsis (JAMA) ACEP Will Not Endorse New Sepsis Guidelines from the Surviving Sepsis Campaign (American College of Emergency Physicians) Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With SepsisThe BLING III Randomized Clinical Trial (JAMA) Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis (Nature Communications) Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study (LANCET: Infectious Diseases) Fungal The Last of US Season 2 (YouTube) Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study (CID) Clinical and Radiological Predictors of Invasive Fungal Sinusitis (OFID) Blood Cultures Contain Populations of Genetically Diverse Candida albicans Strains that May Differ in Echinocandin Tolerance and Fitness (JID) Can fluconazole be used to treat non-resistant Candida (Candidozyma) auris infections? Preclinical PK/PD data from a Galleria mellonella infection model (JID) Parasitic Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial (LANCET: Infectious Diseases) Miscellaneous Bridging the Gap: A Needs Assessment of Resources and Support for International Medical Graduates Navigating Visa-Related Career Decisions in Infectious Diseases (OFID) Number Needed to Treat (NEJM)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #102 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/26 – 3/11/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Measles Outbreak — New Mexico, 2025 (CDC: MMWR) Epidemiology of HMPV and Other Respiratory Viral Infections Among Outpatients, 2016–2022 (OFID) Notes from the Field: Congenital Rubella Syndrome — Florida, 2025 (CDC: MMWR) Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine (Nature Medicine) Bacterial Clinical Outcomes in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Infection: A Cohort Study (JID) Duration of therapy for Pseudomonas aeruginosa bacteremia – a post hoc subgroup analysis from the BALANCE randomized controlled trial (CID) Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries (CID) WHO recommends near point-of-care tests, tongue swabs, and sputum poolingfor TB diagnosis (WHO) Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia (OFID) Balance Versus Bias: Correcting Misinformation About the 2025 ATS Community-Acquired Pneumonia Guidelines (CID) Fungal The Last of US Season 2 (YouTube) Immunomodulation in the Treatment of Disseminated Coccidioidomycosis (CID) Parasitic Comparison of six weeks doxycycline versus six weeks rifampicin or three weeks of the combination of doxycycline plus rifampicin in the treatment of onchocerciasis: a randomized, placebo-controlled, double-blind, phase 2 trial (OFID) Cutaneous Larva Migrans Within the United States Military Health System – Clinical Presentation and Association with Autochthonous Spread or International Travel (OFID) Miscellaneous Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis (Communications Medicine) Rounding Styles on Inpatient Infectious Disease Consult Services: Impact on Education and Patient-Care Delivery (OFID) Possible quality indicators for clinical infectious diseases consultations – results from a hybrid Delphi-nominal group approach and scenario study (CMI: Clinical Microbiology and Infections)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #101 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 2/12 – 2/25/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial (CID) Tecovirimat for the Treatment of Mpox (NEJM) Bacterial Multicounty Outbreak of Salmonella Agbeni Linked to Ice in a Cooler at a County Fair — Illinois, August 2024 (CDC: MMWR) Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality (CID) Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence (Journal of Antimicrobial Chemotherapy) Is three really what we need? Relative effectiveness of benzathine penicillin G and doxycycline treatment regimens for late or unknown duration syphilis in 6 United States jurisdictions, 2016–2021 (CID) Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates (Microbial Drug Resistance) Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection (JAMA Network) Microbial Flora in War Wounds from the Ukrainian Front Line (NEJM) Fungal The Last of US Season 2 (YouTube) Epidemiology of Aspergillosis Diagnoses in U.S. Adults using a National EHR Database, 2013-2023 (OFID) Parasitic State-of-the-Art Review: Chagas Disease—an Enduring Challenge (CID) Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA (Emerging Infectious Diseases) Miscellaneous Ancient bacteria strain discovered in ice cave is resistant to some modern antibiotics(CNN) First genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activities (Frontiers in Microbiology)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS) Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM) Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine) Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID) Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM) Bacterial Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN) Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID) US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature) Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR) Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases) Parasitic Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases) Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene) Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #99 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/15/26 - 1/28/26.

    Host: Daniel Griffin and Sarah Dong

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    Links for this episode Viral Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 (CID) Bacterial Xenodiagnosis to search for Borrelia burgdorferi after antibiotic treatment of Lyme disease: a prospective cohort study (CID) Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia (CID) Methodology Misrepresented: Correcting the Record on the ATS Community-acquired Pneumonia Guideline Process (CID) Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network Surve (Journal of the Pediatric Infectious Diseases Society) Antibiotic Therapy for Uncomplicated AcuteAppendicitis (JAMA) Fungal The Last of US Season 2 (YouTube) Persistence of Symptoms among Commercially Insured Patients with Coccidioidomycosis, United States, 2017–2023 (CDC: Emerging Infectious Diseases) Ophthalmologic evaluation and clinical outcome in candidemia: a seven-year retrospective multicenter cohort study (OFID) Parasitic Postinfectious Syndromes and Long-Term Sequelae after Giardia Infections (CDC: Emergining Infectious Diseases) Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States (OFID) Miscellaneous All About the AAP Recommended Immunization Schedule (healthychildren.org) Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics) Feeling the Vibes: An Investigation into Resident Antibiotic Prescribing Practices (OFID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #98 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/1/26 – 1/14/26.

    Host: Daniel Griffin

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    Links for this episode Viral Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study (JID) Demise of the Milwaukee Protocol for Rabies (CID) Reply to Willoughby on Demise of the Milwaukee Protocol for Rabies (CID) Bacterial Clinical Practice Guideline by Infectious Diseases Society of America (IDSA): 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections: Introduction and Methods (CID) Reassessing the 2023 International Society for Cardiovascular Infectious Diseases Duke clinical criteria for infective endocarditis: Impact of excluding fever and updating diagnostic definition (CID) The diagnostic accuracy of procalcitonin for community-acquired bacteremia: an updated systematic review and meta-analysis (CMI: Clincal Microbiology and Infection) Noninferiority of One HPV Vaccine Dose to TwoDoses (NEJM) About the wastewater program (Colorado: Department of Public & Environment) Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR) Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC:MMWR) Fungal The Last of US Season 2 (YouTube) Candidozyma auris (formerly Candida auris): Resistant, long-lasting, and everywhere (CMI: Clincal Microbiology and Infection) Long-range air dispersal as an important source of environmental contamination in Candida auris clustering: possible infection control implication (Infection Control & Hospital Epidemiology) Parasitic Dermlite Dermatoscopes (dermatoscopes.com) Oral ivermectin versus 5% permethrin cream to treat children and adults with classic scabies: multicentre, assessor blinded, cluster randomised clinical trials (BMJ)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #97 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 12/18/25 – 12/31/25.

    Host: Daniel Griffin

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    Links for this episode Viral Outcomes Related to Bacterial Co-Infection and Antibiotic Use in Adults Hospitalized With Respiratory Syncytial Virus Compared with Influenza (OFID) Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 (Annals of Internal Medicine) Bacterial GeoSentinel Analysis of Travelers' Diarrhea Antimicrobial Resistance Patterns (JAMA Open Network) Rapid direct disk diffusion testing for antibiotic resistance in urinary tract infections: a bacterial concentration-adjusted approach (Microbiology Spectrum) Impact of an Educational Leaflet About Asymptomatic Bacteriuria and Urinary Tract Infection on Antibiotic Preferences Among US Adults ≥65 Years: An Online Randomized Controlled Survey Experiment (OFID) Fungal The Last of US Season 2 (YouTube) Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System (OFID) Parasitic Progress Toward Eradication of Dracunculiasis (Guinea Worm Disease) — Worldwide, January 2024–June 2025 (CDC: MMWR)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #96 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/4/25 – 12/17/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Rabies Cluster Among Steer on a Dairy Farm — Minnesota, 2024 (CDC:MMWR) Incidence of community-acquired pneumonia and herpes zoster in people with HIV based on CD4-count and age in the current antiretroviral therapy era: a longitudinal cohort study (CID) Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays (CID) Bacterial Lactobacillus Bacteremia: A Challenging Condition for Pediatrician (Pediatric Infectious Disease Journal) Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis (NEJM) Zoliflodacin versus ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial (LANCET) Fungal The Last of US Season 2 (YouTube) Compassionate Use of Olorofim for Invasive Mold Infections: A Nationwide Observational Study in France (OFID) Parasitic Eliminating Guinea worm (LANCET: Infectious Disases) Balamuthia mandrillaris Encephalitis in a 12-Year-old Girl: Report of the First Case Diagnosed in Greece (Pediatric Infectious Disease Journal) A Prospective Cohort Longitudinal Study of Human Acute Babesiosis: Quality of Life and Severity of Symptoms Through 1-Year Follow-up (OFID) Body lice and scabies co-infestation among unsheltered migrants, refugees, and asylum seekers and the right to water and sanitation (PLoS Neglected Tropical Diseases) Miscellaneous H.U.S.T.L.E: A Consult Fitness Guide for Infectious Diseases Providers (CID) Seven alternatives to evidence based medical education: an exploration of how we actually teach (BMJ) What does a doctor look like?Asking AI (BMJ) The Receding Specialty of Infectious Diseases and Implications for U.S. Healthcare (OFID) Integrating a host biomarker with a large language model for diagnosis of lower respiratory tract infection (Nature Communications)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #95 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/20/25 – 12/3/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Early low-dose dexamethasone is associated with shorter acute symptom duration in Chikungunya virus infection: a retrospective cohort study (BMC Infectious Diseases) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM) Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection (NEJM) Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human InfectionModel (NEJM) Universal Hepatitis B Vaccination at Birth—Risks of Revising the recommendation (JAMA) Correlates of HIV-1 control after combination immunotherapy (Nature) Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 (CDC: MMWR) Cytomegalovirus-specific cell-mediated immunity for prediction of post-prophylaxis CMV disease in a phase 3 trial of letermovir vs valganciclovir prophylaxis in donor CMV-seropositive recipient CMV-seronegative kidney transplant recipients (CID) An Analysis of Cytomegalovirus-Specific Cell-Mediated Immunity in a Phase 3, Randomized, Placebo-Controlled Trial of Letermovir Prophylaxis in Cytomegalovirus-Seropositive Recipients of an Allogeneic Hematopoietic Cell Transplant (CID) Bacterial Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) Lyme DiseaseIncidence in Massachusetts, 2012-2024 (JAMA: Open Network) Fungal The Last of US Season 2 (YouTube) Aspergillosis-Attributable Mortality in the United States: Analysis of Death CertificateData (CID) Oral itraconazole versus oral voriconazole for treatment-naive patients with chronic pulmonary aspergillosis in India (VICTOR-CPA trial): a single-centre, open-label, randomised, controlled, superiority trial (LANCET: Infectious Diseases) Parasitic Loa loa encephalopathy following treatment with benzimidazole derivatives: A systematic review (OFID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #94 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/11/25 – 11/19/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine) Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID) Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID) HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID) Bacterial Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA) Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID) Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases) A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM) Fungal The Last of US Season 2 (YouTube) Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID) British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases) In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID) Parasitic Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice) WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO) Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases) Miscellaneous IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #93 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/23/25 – 11/10/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral High Prevalence of Varicella Zoster Virus Infection among Persons with Suspect Mpox Cases during an Mpox Outbreak in Kenya, 2024 (ASTMH: AJTMH) Earlier initiation of treatment following HIV acquisition reduces non-AIDS-defining malignancy risk (CID) TWiV 1267: A cancer vaccine and an mpox treatment (MicrobeTV) Cancers Caused by HPV (CDC: Human Papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of the National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine—A Systematic Review (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendations (CDC: Vaccines & Immunizations) Bacterial Consequences of Delaying Surgical Intervention in Patients with Native Joint Septic Arthritis (OFID) Fungal The Last of US Season 2 (YouTube) Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial (LANCET: Respiratory Medicine) Nasal Iodophor to Reduce Candidozyma auris Nasal Carriage in Nursing Home Residents (OFID) Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients (Journal of Pediatric Infectious Diseases Society) Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database (OFID) Genomic Dynamics of the Emergent Candida auris: Exploring Climate-dependentTrends (OFID) Parasitic Evaluation of a One Health public health program based on minimum inputs to control Taenia solium in Madagascar (PLoS Neglected Tropical Diseases) Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood (CID) Miscellaneous Amplifying Our Voices: Fostering Advocacy in Infectious Diseases Fellowship(OFID) Plant-Based Diets and Climate Change, A Perspective for Infectious Disease Provider (OFID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #92 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/9/25 – 10/22/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID) Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID) Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID) Bacterial Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology) Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM) Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection) Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio) Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID) Fungal The Last of US Season 2 (YouTube) Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy) Parasitic Miscellaneous CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID) Infection Control in Carceral Facilities (CID) Infection Prevention and Control in Carceral Settings (CID) The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV) Infected With the Academic Bug (CID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #91 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/25/25 – 10/8/25.

    Host: Daniel Griffin

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    Links for this episode Viral American Academy of Pediatrics Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza(JAMA: Open Network) Flu and Children (CDC: Influenza (flu)) Bacterial Performance of Different Versions of Duke Criteria in Diagnosing Infective Endocarditis in Patients With Intracardiac Prosthetic (OFID) 2023 Duke criteria on Infectious Disease (Puscast 28) Infective Endocarditis and Antimicrobial Timing: A Case for Delay? (OFID) Tularemia: A Storied History, An Ongoing Threat (CID) Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR) Fungal The Last of US Season 2 (YouTube) Risk factors associated with progression to clinical Candida auris infection among adults with previous colonization—Florida, 2019–2023 (CID) Parasitic Public Health Response to the First Locally Acquired Malaria Outbreaks in the US in 20 Years (JAMA: Open Network) Miscellaneous Fever in sepsis revisited: Is a little heat what we need? (OFID)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #90 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/12/25 – 9/24/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide (OFID) Tracking County-Level Measles Cases in the US (JAMA Nework) Tracking measles in US (Hopkins) Pediatric influenza-associated encephalopathy and acute necrotizing encephalopathy (MMWR) Clinical recommendations for Lenacapivir (MMWR)
    Bacterial Primary oral vancomycin prophylaxis to stem an outbreak of Clostridioides difficile infection in intensive care patients (Antimicrob Steward Healthc Epidemiol) Clinical features and treatment strategies of Q fever spinal infection (OFID)
    Fungal Last of Us Season 2 The Pain is in the Brain (J Inf Dis)
    Parasitic Chagas Disease, an Endemic Disease in the United States (MMWR) Fixed-dose ivermectin for Mass Drug Administration (PLoS NTD) Outbreak of eosinophilic meningitis caused by the rat lungworm (Angiostrongylus cantonensis) in South Brazil (Am J Trop Med Hyg) Human monoclonal antibody MAM01 for protection against malaria in adults in the USA (Lancet Inf Dis) Permethrin-Treated Baby Wraps for the Prevention of Malaria (NEJM)
    Miscellaneous Ambient Documentation Technology in Clinician Experience of Documentation Burden and Burnout (JAMA Network Open)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #89 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18/25 – 9/11/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Antibody Responses are Sustained 2 Years Post-Mpox Infection but not Following Modified Vaccinia Ankara–Bavarian Nordic Vaccination (OFID) Intestinal mucosal immune responses to novel oral poliovirus vaccine type 2 in healthy newborns (CID) Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza (NEJM) Fulminant Viral Myocarditis Associated with Thogotovirus (NEJM) Bacterial Risk factors for 30-Day mortality and the role of empirical therapy in Pseudomonas aeruginosa bloodstream infections(Infection) The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United States (CID) The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli(NPJ: antimicrobials and resistance) Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery (OFID) Fungal The Last of US Season 2 (YouTube) Association between Duration of Candidemia and Clinical and Healthcare Resource Utilization Outcomes among Hospitalized Adult Patients with Candidemia Who Received Empiric Treatment with an Echinocandin Across United States Hospitals (CID) Updating the epidemiology of blastomycosis and histoplasmosis in the United States, using national electronic health record data, 2013–2023 (JID) Parasitic Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni (PLoS Neglected Tropical Disease) Miscellaneous

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.

  • On episode #88 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/19/25 – 8/27/25.

    Host: Daniel Griffin and Sara Dong

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    Links for this episode Viral Respiratory Syncytial Virus Immunization Coverage Among Infants Through Receipt of Nirsevimab Monoclonal Antibody or Maternal Vaccination (CDC: MMWR) Bictegravir, emtricitabine, and tenofovir alafenamide versus ritonavir-boosted protease inhibitor-based antiretroviral therapy in people with HIV and viral suppression on second-line therapy in Haiti: an open-label, randomised, non-inferiority trial (LANCET: HIV) Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial (CID) Bacterial Exposure to suppressive antibiotic therapy in women with recurrent urinary tract infections and severity of infections: a retrospective population-based cohort study (BMJ Open) Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomized controlled trials (OFID) Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020 (PLoS Neglected Tropical Diseases) Performance of Tongue Swabs for Tuberculosis Diagnosis in Hospitalized Children Under 5 Years of Age (OFID) Fungal The Last of US Season 2 (YouTube) Towards shorter therapy for candidaemia: defining uncomplicated candidaemia in adults (LANCET: Infectious Diseases) Parasitic Outcomes of Military Blood Donors at Joint Base San Antonio with Reactive Trypanosoma cruzi Antibody Screening (OFID) Cutaneous acanthamoebiasis: Two Cases Highlighting Diverse Histopathologic Findings (Journal of Cutaneous Pathology) Miscellaneous Linezolid-related Optic Nerve Disorders: Insight from a Pharmacovigilance Analysis of the U.S. FDA Adverse Event Reporting System (OFID) Extreme variability in linezolid concentrations in the ICU: A case for routine therapeutic drug monitoring (American Journal of Health-System Pharmacy)

    Music is by Ronald Jenkees

    Information on this podcast should not be considered as medical advice.