Afleveringen
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In this episode of Lab Rats to Unicorns, we delve into the groundbreaking work of Dr. Anant Madabhushi, a distinguished professor at Emory University and a driving force in the application of artificial intelligence to healthcare. As the founder and executive director of the Emory Empathetic AI for Health Institute and the founder of Picture Health, Dr. Madabhushi is revolutionizing the field of oncology through innovative AI-powered diagnostic platforms.
Listen as Dr. Madabhushi shares his personal journey, from his early education in biomedical engineering in India to his pivotal research in digital pathology in the United States. He recounts the experiences, including the loss of his aunt to breast cancer, that fueled his determination to find better ways to diagnose and treat this devastating disease. Discover how the advent of digital pathology, combined with sophisticated machine learning algorithms, has enabled his team to extract unprecedented insights from tissue slides, going beyond traditional diagnostics to predict disease aggressiveness, prognosis, and even response to therapies like immunotherapy.
Dr. Madabhushi also discusses the crucial mission of the Emory Empathetic AI for Health Institute: to ensure that the benefits of AI in healthcare reach all populations, particularly those historically marginalized and underserved globally. He highlights the importance of developing technologies that are not only cutting-edge but also accessible and affordable in diverse healthcare settings. Learn about the challenges and triumphs of translating academic research into impactful commercial solutions through his entrepreneurial ventures. This episode offers a fascinating look into the convergence of AI, medicine, and a deep-seated commitment to improving patient care worldwide.
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Dr. Anh Nguyen has built a career at the intersection of medicine, biotechnology, and public policy, bringing a unique perspective on how scientific innovation translates into real-world impact. As the co-founder and CEO of Alnair Therapeutics, Anh is leading the development of a novel drug delivery platform designed to transform cancer treatment, ensuring that therapies reach their targets more effectively while reducing side effects for patients.
In this episode of Lab Rats to Unicorns, Anh shares his journey from clinical practice to biotech entrepreneurship, detailing the pivotal moments that led him to launch and lead innovative startups. He also reflects on his time working within the FDA and CMS, offering insider insights into the regulatory landscape and how policies like the 21st Century Cures Act shape the future of drug development.
Beyond biotech, Anh discusses the parallels between endurance sportsâhe's completed multiple Ironman triathlonsâand the perseverance required to navigate the highs and lows of building a biotech company.
Whether youâre an entrepreneur, a scientist, or just fascinated by the future of medicine, this conversation dives deep into the challenges, breakthroughs, and leadership lessons that define the evolving world of life sciences. Tune in for an inspiring discussion on resilience, innovation, and the drive to improve patient care through cutting-edge science and strategic execution.
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Zijn er afleveringen die ontbreken?
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In this episode of Lab Rats to Unicorns, we welcome Dede Willis, co-founder and CEO of Orbit Genomics, a trailblazer in the field of diagnostics and life sciences. With a background in engineering and over 25 years of leadership experience, Dede shares how her engineering mindset and entrepreneurial resilience have driven her to build impactful startups that tackle complex challenges.
Dede dives into the mission of Orbit Genomics, exploring how theyâre harnessing the potential of âjunk DNAâ to revolutionize cancer detection and save lives. She also opens up about the challenges of securing funding in the diagnostics space, the importance of fostering team diversity, and the pivotal role government programs like ARPA-H and Cancer Moonshot play in advancing healthcare innovation.
Through thoughtful storytelling and actionable insights, Dede reveals how diagnostics can complement therapeutics, why collaboration is essential to progress, and how startups can thrive by embracing resilience and adaptability. This episode is an inspiring testament to the power of persistence, innovation, and building bridges in science and beyond.
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In this episode of Lab Rats to Unicorns: Rising Stars, we are joined by Dr. Gabe Kwong, a trailblazing biomedical engineer, innovator, and entrepreneur. Gabe is the director of the Laboratory for Synthetic Immunity at Georgia Tech and Emory University, where his groundbreaking research focuses on engineering immune cells as living drugs and developing cutting-edge diagnostics for early disease detection.
Gabe shares his journey from academia to entrepreneurship, founding Glimpse Bio and Port Therapeutics to bring life-saving technologies from the lab to the market. He delves into the transformative potential of synthetic immunity and his work on the Cancer Moonshot initiative, which aims to create an activity-based cancer atlas and advance multi-cancer early detection.
In this candid conversation, Gabe reflects on the importance of mentorship, the power of community spaces like Science Square in Atlanta, and the challenges of aligning science with market demands. Tune in to hear how Gabe is driving innovation, building bridges in the biotech ecosystem, and training the next generation of entrepreneurial researchers. This episode is an inspiring look at the intersection of science, innovation, and the human drive to make a difference.
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In this episode of Lab Rats to Unicorns, John Flavin sits down with Casey McPherson, a musician, songwriter, and rare disease advocate whose life took an extraordinary turn when his daughter, Rose, was diagnosed with HNRNPH2, an ultra-rare neurodevelopmental disorder. Best known for his work as the lead vocalist and songwriter for Alpha Rev and Flying Colors, Casey has spent much of his career crafting powerful music that resonates deeply with audiences. But when faced with the challenges of navigating the healthcare system for rare diseases, Casey turned his creativity, resilience, and determination toward a new mission: advancing precision medicine for underserved patient communities.
As the founder of To Cure a Rose Foundation, Everlum Bio, and Chrysalis Genetics, Casey is revolutionizing the way treatments for rare diseases are approached. In this conversation, he shares how his experiences as an artist helped him find innovative ways to connect, problem-solve, and advocate for change in biotech. Caseyâs journey is a testament to the power of resilience, collaboration, and the unwavering love of a parent determined to make a difference.
Join us as Casey discusses his transition from music to medicine, the importance of collaboration in rare disease research, and how heâs working to create scalable solutions for patient communities that have been overlooked for far too long. This episode is an inspiring exploration of how passion and creativity can drive impact in even the most unexpected arenas.
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This episode of Lab Rats to Unicorns features an inspiring conversation with Julia Vitarello, founder of Milaâs Miracle Foundation and a trailblazer in the field of individualized genetic therapies. Julia shares the story of her daughter Mila, who was diagnosed with a rare and fatal genetic disease, Batten disease, at age six. Confronted with a system ill-equipped to handle ultra-rare conditions, Julia embarked on a transformative journey to develop Milasen, the first-ever genetic therapy tailored for a single individual.
Through resilience and collaboration, Julia mobilized a global network of scientists, regulators, and supporters to create a treatment that set a precedent for a new approach in medicine. Beyond her daughterâs story, Julia reflects on the systemic barriers families face when accessing life-saving treatments and how her foundation is addressing these challenges. She explores the future of healthcare, advocating for changes to regulatory and reimbursement models to scale access to innovative therapies for rare disease communities. Juliaâs pioneering work is a testament to the power of advocacy, science, and the unwavering determination of a mother to spark a revolution in medicine.
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In this episode, John Flavin sits down with Dr. Ivan Liachko, co-founder and CEO of Phase Genomics, a company at the forefront of genomics and microbiome research. Ivan shares his journey from a young immigrant fascinated by biology in Ukraine to a biotech leader based in Seattle. His academic path began with a keen interest in genetics, leading him to work at the University of Washington, where he honed skills in both genetics and computer science. Dr. Liachko discusses how Phase Genomics emerged from a passion project to solve unique biological challenges, evolving into a full-fledged company offering genome assembly services, microbiome diagnostics, and groundbreaking cancer diagnostic tools. Ivanâs focus on innovation is clear, as he reflects on the importance of courage, community, and resilience when transforming science into industry. As the conversation unfolds, Ivan delves into his vision for future scientific breakthroughs and the value of an ecosystem that supports unconventional thinking.
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In this insightful episode of Lab Rats to Unicorns, Steve Lehmann sits down with Dr. Zhenpeng Qin, Associate Professor of Mechanical and Bioengineering at the University of Texas at Dallas. Dr. Qin shares his groundbreaking work in biomedical engineering, focusing on the development of nanomaterials to advance diagnostics and therapeutic delivery. From innovations in nanoparticle technology to exploring the blood-brain barrier for treatment delivery, Dr. Qinâs journey reveals the power of interdisciplinary research. This episode dives into the evolution of his career, his shift from traditional mechanical engineering to medical applications, and his vision for the future of biomedical technology.
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Join us for a conversation with Dr. Raghu Kalluri, a leading figure in cancer biology, who serves as the Chair of the Department of Cancer Biology at MD Anderson Cancer Center. With over 300 publications, multiple successful biotech ventures, and groundbreaking work in exosome research, Dr. Kalluri discusses the intricate relationship between science, medicine, and industry, his career path from researcher to entrepreneur, and his exciting vision for using innovation to transform cancer care.
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Join us on Lab Rats to Unicorns as we dive into the career of Michael Torres, CEO of Crossbridge Bio. With a Ph.D. in cancer biology and a background in equity research, Michael has been at the forefront of developing cutting-edge oncology treatments. In this episode, he discusses the evolution of antibody-drug conjugates (ADCs) and the process of building biotech companies in the Texas innovation ecosystem, as well as his personal journey from researcher to CEO.
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Join us on Lab Rats to Unicorns as we dive into the inspiring journey of Dr. Jochen Reiser, President of UTMB and CEO of UTMB Health System. A nephrologist, healthcare executive, and biotech entrepreneur, Jochen shares insights from his transition into the U.S. medical landscape, his pioneering research in kidney disease, and the founding of Walden Biosciences. This episode explores the exciting intersection of clinical care, research, and innovation.
Key Topics:
Jochenâs transition from Germany to the U.S. and his research in nephrology Founding and commercializing Walden Biosciences for kidney disease Leading UTMB as President and fostering innovation Balancing clinical care, research, and education in healthcare Collaboration and team-building in the biotechnology sector
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Join Steve Lehmann & Jeremy Langsam from Portal's Stargaze team on a bimonthly segment of Lab Rats to Unicorns: Rising Stars. In this episode, they explore the groundbreaking work of Zachi Attia, the Director of Artificial Intelligence at Mayo Clinic. With a rich background in electrical engineering and a Ph.D. in Bioinformatics, Zachi discusses his pivotal role in advancing AI models that predict and screen cardiovascular diseases. From his innovative research to real-world applications that are saving lives, this episode offers an inspiring look into the future of healthcare.
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In this captivating episode of Lab Rats to Unicorns, we journey into the universe of biotechnology with Steve Lehmann, Director of Venture Operations, and Jeremy Langsam, Venture Analyst at Portal Innovations.
In this episode, Steve and Jeremy share their insights into the relay race of innovationâfrom the "aha" moments in the lab to creating groundbreaking companies with global impact. They delve into the evolution of innovation ecosystems and how tools like Stargaze allow us to plant the seeds for future growth by identifying emerging clusters and talents.
Through vivid metaphors and real-world examples, Steve and Jeremy illuminate the complex process of turning cutting-edge science into lifesaving treatments and products. Whether you're an aspiring entrepreneur, a seasoned scientist, or simply curious about the future of biotech, this episode is packed with inspiration and wisdom from those at the forefront of scientific discovery.
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In this episode, Dr. Walter E. Massey shares insights from his illustrious career in science and academia, detailing his journey, evolving focus, and key advancements in physics that have shaped his work. He discusses significant leadership decision points, his approach to decision-making, and offers guidance on preparing for impactful choices. Reflecting on his tenure at the National Science Foundation, Dr. Massey highlights the crucial role of government in scientific research and policy.
He explores the enriching intersection of disciplines, particularly between art and science, emphasizing how such fusions drive innovation. Personal inspirations, including influential mentors, books, and events, are shared to illustrate his life philosophy and career decisions. Dr. Massey also delves into the cultural and community aspects of science, discussing the responsibilities of educators and leaders in shaping the future of scientific innovation for greater social impact.
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Episode 54 of LRTU wants us to know about Tony Martignetti, the founder and chief inspiration officer at Inspired Purpose! With over 25 years of experience in the life sciences and tech sectors, Tony brings a wealth of knowledge and a unique perspective on leadership. He shares his journey from being a pre-med major to holding pivotal roles in biopharma companies like Genzyme and Sarepta, before transitioning to a career in leadership coaching. Throughout the episode, Tony emphasizes the importance of curiosity, compassionate leadership, and creating environments that foster innovation and connection. His grounded leadership framework, centered on the three C'sâconnection, curiosity, and compassionâoffers valuable insights for leaders at all levels.
Tony also discusses his bestselling books, "Climbing the Right Mountain" and "Campfire Lessons for Leaders," where he delves into finding fulfillment in the journey rather than the destination. He highlights the significance of embracing a beginner's mind, encouraging leaders to ask questions and remain open to new ideas. Through meaningful anecdotes and practical advice, Tony illustrates how leaders can unlock their true potential and inspire their teams. Join us for an inspiring conversation that explores the transformative power of curiosity and the impact of compassionate leadership in driving innovation and success.
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Join us on episode 53 of Lab Rats to Unicorns as we sit down with Solomon Wilcots, a former NFL player who has transitioned into a health advocate. Solomon invites us on his remarkable journey from the competitive arenas of professional sports into the insightful world of broadcast television, and further into the impactful realm of health communications. He discusses the vital roles of teamwork and community, principles ingrained during his sports career, which now fuel his mission to advance medical science and patient care, with a particular focus on brain health and Alzheimer's research. Tune in to discover how Solomon utilizes his extensive platform to drive global change and why he believes continuous learning is essential for making a significant impact.
Throughout his diverse career, Solomon has been a prominent figure across broadcast television and radio, notably as a game analyst for CBS Sports and a contributor to the NFL Network. His broad experience includes roles as a studio analyst and sideline reporter, covering major events such as multiple Super Bowls and NCAA basketball tournaments. Shifting focus from sports, Solomon now plays a crucial role in health communications as the leader of the Sports-Health Division at Russo Partners LLC. In this capacity, he spearheads initiatives like "Huddle Up for New Alzheimer's Treatments," which has dramatically increased enrollment in clinical trials. His efforts also involve creating content that links biotech innovations with a wider audience, further illustrating his profound impact across both the sports and health sectors.
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In this episode of "Lab Rats to Unicorns," recorded at TMC's Helix Park in Houston during a Portal Pours event, we're joined by a distinguished panel led by featured host Ritu Shah, a seasoned expert in the biopharma industry and Managing Director at Portal Innovations. The conversation features:
Sarah Hein, the visionary founding CEO of March Biosciences, a trailblazer in clinical-stage cell-therapy, with a rich background in cancer therapeutics and antibody therapeutics platform technologies. Rahul Aras, a dedicated executive with a robust 15+ years in the pharma/biotech sector, currently leading the charge in early-stage technology advancement and business development, recognized for his role at Iterion Therapeutics. Michael Torres, an entrepreneur with a fervent mission to turn science into medicine, leveraging his experience in biotech company formation and equity research to make significant strides at Crossbridge Biotech.Together, they delve into the dynamics of Houston's biotech ecosystem, sharing their unique perspectives on innovation, the challenges of startup culture, and the path forward in transforming patient care.
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In this live taping of Lab Rats to Unicorns, John Flavin and Jeff Karp discuss the challenges and triumphs of bringing lab research to market, the evolving landscape of biotech startups, and the importance of interdisciplinary collaboration in driving scientific breakthroughs.
Dr. Jeff Karp is a renowned figure in the biotechnology sector, known for his groundbreaking work and innovative approaches in the field. With a career that bridges both academic research and industry application, Dr. Karp has been at the forefront of developing cutting-edge biotechnological solutions to some of healthcare's most pressing challenges. Jeff is the Distinguished Chair at Brigham and Women's Hospital, a Professor at Harvard Medical School, Affiliate Faculty at MIT & The Broad Institute, and Principal Faculty at the Harvard Stem Cell Institute His expertise spans a range of areas, including drug delivery systems, regenerative medicine, and tissue engineering. Dr. Karp's work is characterized by a commitment to translational research, aiming to bring laboratory discoveries into practical medical use. His leadership in various biotech initiatives and collaborations has been instrumental in driving forward the boundaries of medical science and patient care. Jeff has won numerous awards around his innovations and entrepreneurial successes.
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In this episode of "Lab Rats to Unicorns," we're thrilled to spotlight Ritu Shah, the Managing Director at Portal Innovations, whose distinguished career in the biopharma industry spans over two decades. Ritu's unparalleled expertise shines in her role, where she's instrumental in driving growth and enhancing the value of portfolio companies. Specializing in steering early-stage companies towards key milestones and securing funding rounds, her strategic prowess has been key to numerous mergers & acquisitions, company formations, and operations.
Ritu Shah's journey includes significant roles as a fractional executive, showcasing her versatility through part-time contracted positions as a senior executive with Dimension Inx., head of operations and senior advisor with Reax Biotechnologies, and CEO of ClostraBio. At Portal, she spearheaded the innovative Ex^3 fractional C-suite model for life science clients, marking a significant milestone in her illustrious career. Join us as we explore the intricate dynamics of biotech's fast-evolving landscape, illuminated by Ritu Shah's remarkable insights and achievements.
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In this episode, we venture into the intricate world of life science innovation spaces with James Lewis and Mason Ailstock. From the nuances of creating standout spaces that cater to diverse innovator types to the importance of location in driving differentiation, we dissect what truly makes an innovation hub thrive. As we spotlight their landmark projects, James and Mason share insights into pivotal decision points that have shaped their work. Beyond the structures and spaces, we also delve into the Atlanta market's present dynamics and its prospective horizon. Through it all, the personal journeys of our guests enrich our understanding, merging the professional with the personal in a tale of ambition and accomplishment.
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