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This episode of MedEvidence! features a compelling discussion between cardiologist and medical researcher Dr. Michael Koren and 20th U.S. Surgeon General Dr. Jerome Adams. Dr. Adams shares his unique journey from growing up in rural Maryland to becoming the nation's top doctor, highlighting the role of personal experience in shaping his commitment to public health. The conversation delves into the challenges of navigating evidence-based medicine during crises like COVID-19, the importance of addressing social determinants of health, disease management versus health promotion, and the tension between individual patient care and public health priorities. With insights into policymaking, scientific communication, and trust-building, this episode offers a thoughtful exploration of how evidence shapes decisions in medicine and public health.
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Unlock the secrets to successful clinical trials with Dr. Michael Koren and Doug Denham in part 2 of this podcast. The doctors explore participant retention strategies that make a difference to science and to patients. From obesity studies to cholesterol conditions, Drs. Koren and Denham share their experiences with keeping participants engaged and ensuring trial success. They discuss the importance of personal relationships with patients, maintaining a supportive environment, and the power of setting realistic expectations.
The doctors also emphasize the necessity of clear communication, especially during Serious Adverse Events, and the importance maintaining study blindness to prevent bias. The doctors close by discussing the importance of trial volunteers and how the industry can improve communication after a trial is complete.Be a part of advancing science by participating in clinical research.
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Dr. Michael Koren and Kevin Geddings discuss New Year’s health resolutions and how clinical research can help achieve them. The conversation highlights the ancillary benefits of participating in research, including expert guidance, hands-on care, and reinforced healthy habits. Dr. Koren also explains that exercising regularly, managing cardiovascular health, and quitting smoking are keys to achieving health goals.
Recording Date: December 30, 2024Be a part of advancing science by participating in clinical research.
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Join Dr. Michael Koren as he sits down with Dr. Doug Denham, a Certified Principal Investigator with extensive experience in family medicine and obesity research for the first of this two part series as they discuss the lengthy process of becoming a Certified Principal Investigator. The doctors discuss new obesity medications that are being investigated through clinical research and how difficult it can be to retain patients who aren't reaching their weight loss goals in an obesity study.
Doctors Koren and Denham discuss patient engagement and compliance and explore strategies that keep participants motivated throughout the trial process. They talk about the importance of personal connection in maintaining participant interest, revealing how understanding individual motivators can significantly impact scientific success. Dr. Denham emphasizes the importance of retaining participants for essential endpoint visits, even if they choose to stop taking the investigational product.
Learn about the benefits of offering open-label treatments post-unblinding, which can help patients even after an initial study has completed.Be a part of advancing science by participating in clinical research.
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Ever misheard a song lyric and discovered the truth years later? Join cardiologist and research scientist Dr. Michael Koren as he compares misheard lyrics to the difficulty in understanding complex medical issues. Dr. Koren and host Kevin Geddings explain how participating in clinical trials can offer surprising insights into your health and enhance your understanding of medical data. The two then talk about the expansive range of clinical trials available.
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Doctors Michael Koren and Mitchell Rothstein discuss the role of government in healthcare. They demonstrate the differences between functional agencies and political agendas, explore where politics and healthcare intersect, and look at how objective, unbiased data can answer complex questions where politics can't.
The doctors discuss the government agencies in the medical field, including the FDA, OHRP, NIH, and the CDC. Other topics include healthcare disparities, vaccines, gender reassignment surgeries, and research as a care option.
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What if you stumbled upon your calling purely by accident? Join Dr. Michel Koren as he sits down with Norm Goldfarb, a structural innovator in the clinical research field. They discuss his unexpected journey from a technology startup CEO during the chaotic days of the internet bubble burst to becoming a cornerstone in clinical research innovation. Norm opens up about how establishing a clinical research site in San Francisco drove him to ending the inefficiencies in the system. Norm found his niche by organizing conferences, publishing journals, and streamlining clinical trial processes.
Navigating Clinical ResearchAdvancing Clinical Research Quality and EfficiencyImproving Clinical Trial Enrollment Efficiency
Join us for a deep dive into the complex ecosystem of clinical research, where the dedication of professionals plays a crucial role in advancing medical knowledge. We uncover how strategies like risk-based monitoring and quality by design are revolutionizing the industry, ensuring both participant safety and research integrity.
Catch Koren's Key Takeaways:Recording Date: October 25th, 2024
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Asthma is more than a condition—it's a challenge shaped by triggers, environment, and access to care. Join Dr. Steve Dorman, a leading allergy immunologist, as he unpacks asthma's complexities, from the impact of geography and air pollution to socioeconomic hurdles. Learn about tailored treatments, the role of biomarkers, and emerging therapies offering hope for better asthma management. With insights, humor, and practical tips, this episode explores how innovation is transforming care. Visit MedEvidence.com for more!
Asthma Management and Treatment OptionsClinical Trials for Asthma TreatmentAsthma Medication Administration Alternatives
Catch Koren's Key Takeaways:Recording Date: November 13, 2024
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In this episode Dr. Michael Koren shares a story about a clinical trial participant who discovered unexpected benefits of clinical research. Though initially seeking help for a cardiac condition, she found value in flu vaccine trials, gaining protection for herself and her family while using the financial compensation to brighten her holidays.
Dr. Koren and Kevin Geddings also discuss how clinical trials provide participants with an exceptional care option that is free from the time pressures of traditional medical practice. They emphasize how research participation can educate individuals, connect families to new opportunities, and foster a sense of community involvement.
Recording Date: December 9th, 2024Be a part of advancing science by participating in clinical research.
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Discover the groundbreaking innovations at the crossroads of cardiology and gastroenterology with Dr. Michael Koren and Dr. Ali Lankarani, a gastroenterologist and advanced endoscopist. Learn how these medical fields borrow and refine techniques from each other to revolutionize patient care. Dr. Lankarani shares how personal experiences and family influences shaped his career. Doctors Koren and Lankarani discuss how cutting-edge technologies like endoscopic ultrasound are transforming surgical procedures, offering less invasive alternatives that leave no visible scars.
🗝Advancing Medical Research With Cardiologists🗝Innovation in Gastrointestinal Stricture Treatment🗝Clinical Trials for GI Stricture Treatment
The discussion they focuses on Dr. Lankarani's research on using drug-coated balloons to treat strictures in the GI tract. Strictures and shrinkages or blockages in the GI tract that can cause difficulty swallowing and other symptoms. The doctors discuss shortcomings of current care and how early results in clinical trials show promise for reducing complications.
Catch Koren's Key Takeaways:Recording November 4, 2024
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Feeling queasy and uneasy about catching norovirus (stomach flu) during your holiday plans? Join Dr. Michael Koren and Ken Geddings as they discuss this highly contagious virus, how it can spread, and why conventional hand sanitizers won't save you. With the holiday season upon us, understanding how this virus transmits - even through the air in places like restaurants - is crucial for keeping your celebrations merry and healthy. Dr. Koren also talks about an investigational vaccine targeting norovirus. From practical advice to scientific insights, learn what you need to do to protect yourself and your loved ones; whether gathering with family, taking a cruise, or simply dining out.
Recording Date: December 2, 2024Be a part of advancing science by participating in clinical research.
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Doctor Michael J. Koren welcomes his longtime colleague Doctor Victoria Helow on this episode where they talk about the stomach flu; norovirus. Dr. Helow, a pediatrician, pediatric emergency specialist, and clinical researcher shares her experience with norovirus, its effects, how to fight it, and why it’s so dangerous in hospitals, communal retirement homes, and cruise ships. The doctors also investigate why norovirus can be such a challenge to fight and control, and why many sterilization techniques don’t work on this stubborn virus.
Norovirus is also known as the "stomach bug"Norovirus is highly infective and spreads easilyHospitals and elderly homes are susceptible; not just cruise shipsHand sanitizer doesn't work on norovirus
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Recorded November 19, 2024Be a part of advancing science by participating in clinical research.
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Imagine booking a dream cruise only to find out that the amenities are fully booked before you even set sail. This frustrating experience resonates with the hurdles many face in accessing timely healthcare. Join us as cardiologist and research scientist Dr. Michael Koren connects these dots. He illustrates how participating in clinical trials can improve your healthcare experience. Dr. Koren introduces the concept of "research as a care option," showing how in the pursuit of medical advancement, clinical trials also provide access to personal and attentive care.
Recording Date: November 25th, 2024Be a part of advancing science by participating in clinical research.
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What if you could arm yourself with the knowledge to protect your family against the flu season's viral threats? In our latest MedEvidence episode, Dr. Stella Hayes guides us through the complexities of flu season preparation, emphasizing the vital role of vaccinations and strategic precautions. Drawing from her extensive career experiences and personal stories, she highlights the looming threats of RSV, COVID-19, and Influenza while providing actionable advice to safeguard your health.
Preparing for the Flu SeasonOptions for Flu and RSV VaccinesViruses and Long-Term EffectsViral Seasons and Immunity BoostersUnderstanding the Spanish Flu and Vaccines
Key Takeaways:Recording Date: October 25, 2024
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Dr. Michael Koren discusses the stagnation of heart disease and stroke prevention, which was discussed at the American Heart Association meeting in Chicago. Dr. Koren and Kevin Geddings talk about factors flattening the curve of cardiac progress, including increasing obesity and diabetes, limited access to medicine, and growing skepticism towards the scientific and medical community as a whole.
The importance of medical data and evidence is underscored as Dr. Koren memorialized a lifelong friend to lung cancer, atrial fibrillation, and stroke as a result of cigarette smoking. He discusses how medical science has big effects across the community, but that the impacts of science, medicine, and clinical trials to the individual and their loved ones is incalculable.
Recording Date: November 19, 2024Be a part of advancing science by participating in clinical research.
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Explore the psychological intricacies that shape healthcare attitudes as we engage with industrial psychologist Dr. Chris Steilberg. Uncover the secrets behind how emotionally charged schemas in our brains forge beliefs that resist even the most compelling facts. Through motivational interviewing, we reveal ways to build trust and shift attitudes between patients and healthcare providers. Hear the remarkable story of Dick Cheney's battle with smoking addiction following multiple heart attacks, illustrating the uphill challenge of changing well-entrenched habits and beliefs in the realm of health.
Understanding Healthcare Attitudes and Motivational ChangeBreaking Down Attitudes Through Surprising AbsurdityTransforming Beliefs and Behavior Through Innovation
Dive into a thought-provoking narrative on how the COVID-19 mask mandates served as a societal mirror, highlighting deep-seated divisions and belief "firewalls." By sharing a personal story from the gym, we open up strategies that use surprise and absurdity to dismantle these barriers and promote open dialogue. Discover the transformative methods of psychiatrist Albert Ellis and the exciting potential of psychedelics in reshaping mental frameworks. This episode promises a rich exploration of shifting deeply held beliefs through innovative approaches, underscoring the gradual nature of these profound changes for enhanced healthcare outcomes.
Koren's Key Three Takeaways:Recording Date: October 7, 2024
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Discover why heart disease might be America's most formidable adversary, as Dr. Michael Koren and Kevin Geddings of WSOS Radio discuss the parallel between the annual death toll from heart disease and all U.S. wars, highlighting the urgent need to shift our battle strategy. With Veterans Day as our backdrop, we reflect on the halted progress in reducing heart disease and stroke mortality after significant gains from the 1980s to the early 20-teens. What factors are contributing to this stagnation, and how can groundbreaking research spearhead a new era of medical interventions?
Recording Date: November 11, 2024Be a part of advancing science by participating in clinical research.
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Can you imagine your body's defense mechanism mistakenly turning on itself, like a loyal guard suddenly becoming a double agent? Join us as we unravel the complexities of the immune system and its sometimes unpredictable behavior that leads to autoimmune diseases. You'll gain insights into why diagnosing these conditions can be such a lengthy and intricate journey, often involving a parade of specialists. Our particular focus shines on lupus, especially systemic lupus erythematosus (SLE), where we investigate its systemic effects, possible triggers, and the intriguing role of genetics.
Understanding Autoimmune DiseasesUnderstanding Scleroderma and Rheumatoid ArthritisEngaging in Clinical ResearchOrigins of Lupus Name
Take a closer look at scleroderma and rheumatoid arthritis, where the body's own tissues become unfamiliar battlegrounds. Discover how excessive collagen can tighten skin and impact organs in scleroderma, and how rheumatoid arthritis brings its painful touch to the joints, predominantly affecting women. We'll reveal surprising risk factors, like smoking and viral infections, and keep you engaged with playful questions that invite you to test your knowledge while learning about the nuances of these conditions.
The journey doesn't stop at understanding; it extends to action. We emphasize the importance of staying informed and participating in clinical research to not only benefit personal health but also contribute to scientific advancements. Explore the promising developments in therapies, like JAK inhibitors, and learn how you can be part of this evolving landscape through clinical trials. As we wrap up, we'll delve into the medieval origins of the term "lupus," where historical anecdotes bring a unique perspective to this ancient condition. Thank you for tuning in to this informative and thought-provoking session of the MedEvidence podcast.
Koren's Key Takeaways:Recording Date: October 24, 2024
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Fear is more than just a survival mechanism—it's a key element that differentiates human intelligence from artificial intelligence. On this week's MedEvidence Monday Minute, Dr. Michael Koren shares his perspective on why fear, often seen as a barrier, is actually a fundamental facet of our intelligence and decision-making. Unlike AI, humans are inherently guided by this fear filter, which shapes our culture and interactions. Dr. Koren delves into how this contrast with AI could lead to unintended consequences, as AI lacks the deeply ingrained caution that fear engenders in us.
Recorded Date: November 4, 2024Be a part of advancing science by participating in clinical research.
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Ever wish you could sit down with a doctor for over 30 minutes to talk about your lab results? In this MedEvidence episode, Danny Chu gets that experience and shares it with you. Our conversation goes beyond Danny's personal stories to examine the vital role of HDL, LDL, and lipoprotein-a Lp(a) levels in cardiovascular health. We discuss how lifestyle choices like intermittent fasting and regular exercise and how genetic hurdles impact your health. Danny's personal experiences highlight the need for a tailored approach to managing heart health, while also considering the potential benefits of statins and the importance of ongoing clinical research.
The episode wraps up with a thought-provoking discussion on the importance of high-quality evidence in medical research and the joy of scientific discovery. Drawing inspiration from luminaries like Richard Feynman, we emphasize how curiosity and a passion for understanding complex systems drive progress in science and health. Tune in to explore these fascinating topics and gain insights into managing cardiovascular risks, backed by rigorous research and a deep appreciation for the wonders of science.
Recording Date: October 7, 2024Be a part of advancing science by participating in clinical research.
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