Afleveringen
-
Ed Stern (Bar-Ilan University, Israel) discusses corticostriatal networks in mouse models of Alzheimer’s disease.
Duration: 42 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Recorded as a panel discussion following the UTSA Neurosciences Institute’s 2018 research symposium. The group discusses the tripartite synapse concept, which was coined by two of our panelists, Phil Haydon and Alfonso Araque, in the late 1990s. The group considers the diverse mechanisms of astrocyte-neuron communication, and the magnitude of how we are beginning to redefine the neural circuits of behavior and disease based on this new framework. Hosted by Salma Quraishi.
Duration: 49 minutes
Discussants:(in alphabetical order)
The Panelists
Alfonso Araque, Robert & Elaine Larson Neuroscience Research Chair, University of Minnesota Medical School
Philip Haydon, Annetta and Gustav Grisard Professor of Neuroscience, Sackler School of Medicine, Tufts University
Erik Herzog, Professor of Biology, Washington University in St. Louis
Carlos Paladini, Professor of Biology, UTSA
Joining the discussion
James Lechleiter, Professor of Cells Systems & Anatomy, UT Health San Antonio
Salma Quraishi, Assistant Professor of Research, UTSA
Matt Wanat , Assistant Professor, UTSA
Charles Wilson, Ewing Halsell Chair, Director of the UTSA Neurosciences Institute
acknowledgement: JM Tepper for original music. -
Zijn er afleveringen die ontbreken?
-
Marco Gallio (Northwestern) talks about temperature sensation in Drosophila as a “fruitful” model system for examining sensory encoding and propagation of representations through a relatively reduced sensorimotor system.
Duration: 39 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Lindsey Macpherson (Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Dwight Bergles (Johns Hopkins) discusses his work characterizing a fourth mysterious class of CNS glial cells, called oligodendrocyte precursor cells.
Duration: 46 minutes
Discussants:(in alphabetical order)
Carlos Paladini (Professor, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Aurelio Galli (UAB) discusses the biophysics of the dopamine transporter, its relevance to disease, and how he is leveraging drosophila to study behavioral phenotypes of dopamine transporter mutations.
Duration: 35 minutes
Discussants:(in alphabetical order)
Carlos Paladini (Professor, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Matt Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Lori Knackstedt (UF Gainesville) discusses glutamate homeostasis mechanisms in the nucleus accumbens in mediating relapse to cocaine-seeking in rodent models of cue-induced extinction and abstinence.
Duration: 46 minutes
Discussants:(in alphabetical order)
Carlos Paladini (Professor, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Matthew Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Veronica Alvarez (NIAAA) discusses using drugs of abuse to probe D2 mechanisms in striatal circuitry, and effects on behavior.
Duration: 46 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Carlos Paladini (Professor, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Matthew Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Ann Graybiel (MIT) discusses her work on cortical-basal ganglia loops and habit formation.
Duration: 46 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Carlos Paladini (Professor, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Matthew Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Dean Buonomano (UCLA) talks about strategies that neural networks might use to store information about time in the states of neural networks.
Duration: 38 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Recorded as a panel discussion following the UTSA Neurosciences Institute’s 2017 research symposium on September 14, 2017. Hosted by Salma Quraishi.
Duration: 38 minutes
Discussants:(in alphabetical order)
Andre Fenton, Professor of Neural Science, NYU
James Knierim, Professor of Neuroscience, Johns Hopkins
Isabel Muzzio, Associate Professor, UTSA
A. David Redish, Distinguished McKnight University Professor, U of Minnesota
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Suzanne Haber (U Rochester Med Ctr) talks about defining anatomy and structural connections in the context of function in the cortico-basal ganglia-thalamic system.
Duration: 37 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Mark Shapiro (UT Health, San Antonio) talks about visualizing how the anchoring protein AKAP79/150 orchestrates functional coupling of ion channel assemblies using super-resolution microscopy.
Duration: 39 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Fidel Santamaria (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Joanna Phillips (UCSF) fields our questions about the cellular microenvironment: how cell signaling and interactions are mediated by glycocalyx proteoglycans and components of the extracellular matrix. The discussion touches on how these cell surface and microenvironment factors impact migration and cancer proliferation.
Duration: 44 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Annie Lin (Asst Professor, UTSA)
Asif Maroof (Asst Prof, UTSA)
Fidel Santamaria (Assoc Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Jim Surmeier (Northwestern University) talks to us about integrating circuit, ion channel and bioenergetic vantage points to define quantitative, neuron-specific mechanisms of pathology in Parkinson’s disease. He guides the group through a discussion of how his hypothesis-driven approach is informing an exciting new clinical trial for slowing the progression of Parkinson’s disease.
Duration: 47 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Asif Maroof (Asst Prof, UTSA)
Carlos Paladini (Professor, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Matt Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
James Tepper (Rutgers Newark) joins us 10 years down the line to revisit the topic of our inaugural podcast discussion, which centered on the diversity and origins of striatal interneurons. A number of the original group are joined by some new faculty to consider how the field has expanded and evolved in the last decade.
Duration: 43 minutes
Discussants:(in alphabetical order)
Alfonso Apicella (Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Asif Maroof (Asst Prof, UTSA)
Carlos Paladini (Professor, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Alan Lerner (Case Western Reserve) offers his perspective as a clinician-scientist in understanding the scope of Brain Health as a “big science” initiative. He describes how a broad alignment of public health, medical, clinical and basic science perspectives are informing new perspectives on the treatment and prevention of neurodegenerative diseases and dementia.
Duration: 38 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Asif Maroof (Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
acknowledgement: JM Tepper for original music. -
Gemma Casadesus-Smith (Kent State) discusses new strategies in thinking about Alzheimer’s disease and its prevention, and what we understand about the disease process through clinical indicators. The group takes on some hard questions about the approaches being used to guide clinical trials, and why some ideas appear to linger past their prime.
Duration: 52 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Hyoung-gon Lee (Assoc Prof, UTSA)
Asif Maroof (Asst Prof, UTSA)
George Perry (Dean, College of Science UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Nick Hollon (Fellow, Xin Jin Lab, Salk Institute) leads us in a fantastic discussion on neuroeconomic approaches to understanding the neural correlates that govern value-based decision making.
Duration: 41 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Carlos Paladini (Professor, UTSA)
Matt Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
Todd Troyer (Assoc Prof, UTSA)
acknowledgement: JM Tepper for original music. -
Christiane Linster (Cornell) discusses the theory and experimental realities at play in modeling learning, memory and neuromodulation in the olfactory system of rodents.
Duration: 40 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. -
Bennet Ibey (Air Force Research Laboratory) discusses the biophysics of how membranes react to electric field pulses. The discussion centers around our reference point for this phenomenom, electroporation.
Duration: 48 minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Fidel Santamaria (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music. - Laat meer zien