Afleveringen
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On this episode of the Top 200 Drugs Podcast, I cover medications 146-150. This podcast includes; sevelamer, dalteparin, sertraline, clonazepam, and irbesartan.
Sevelamer is a phosphate binder that is used to treat hyperphosphatemia in patients with chronic kidney disease.
Dalteparin is a low molecular weight heparin product that is used to prevent and treat blood clots.
Sertraline is a commonly used SSRI that can be helpful in managing depression and anxiety.
Clonazepam is a benzodiazepine that can be used for acute relief of anxiety. Sedation, confusion, and fall risk are potential adverse effects.
Irbesartan is an ARB that can be used for hypertension. Hyperkalemia and angioedema are two adverse effects to be aware of. -
On this top 200 drugs podcast, we are covering medications 141-145. Raltegravir, ustekinumab, meloxicam, infliximab, and Nighttime Cold and Flu are the medications that are covered on this episode.
Raltegravir is an integrase inhibitor that is used to manage HIV infection and may also be used for post-exposure prophylaxis.
Ustekinumab is a monoclonal antibody that can help reduce inflammation by binding interleukins.
Meloxicam is an NSAID used for pain and anti-inflammatory purposes. GI bleeding risk is a top adverse effect to monitor for.
Infliximab is a monoclonal antibody that can be used for autoimmune disorders such as psoriatic arthritis, rheumatoid arthritis, ulcerative colitis, and Crohn's disease.
Nighttime Cold and Flu medication is a combination product that often includes acetaminophen, dextromethorphan, and doxylamine. -
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On this episode, I cover cinacalcet, solifenacin, haloperidol, hydrocortisone (focused on topical), and insulin NPH.
Cinacalcet is a calcimimetic medication that can be helpful in hyperparathyroidism and useful for managing hypercalcemia.
Solifenacin is a urinary antimuscarinic used primarily for overactive bladder. It is an anticholinergic medication that can be problematic in our geriatric patients.
Haloperidol is a first generation antipsychotic that has a high incidence of EPS relative to many newer antipsychotics.
Hydrocotorisone is one of the most common topical corticosteroids that can be used to reduce inflammation and redness from skin reactions.
Insulin NPH is an intermediate acting insulin that is meant to be given on a routine basis. It has fallen out of favor since insulin glargine and other long acting agents allow for few injections and more stable kinetics. -
On this episode of the Top 200 drugs podcast from Real Life Pharmacology, I cover medications 131-135 which include enoxaparin, methylphenidate, rosuvastatin, denosumab, and dabigatran.
Enoxaparin is an injectable anticoagulant that can cause heparin-induced thrombocytopenia.
Methylphenidate is a stimulant medication that can be used to treat ADHD. Cardiovascular adverse effects are possible.
Rosuvastatin inhibits HMG-CoA Reductase which helps lower LDL in the management of hypercholesterolemia.
Denosumab is a monoclonal antibody that is indicated for osteoporosis and may cause hypocalcemia.
Dabigatran was one of the first direct oral anticoagulants to be produced. It is dosed twice daily and has warnings about use in patients over the age of 75. -
In this episode of the Top 200 Drugs Podcast, we cover medications 126-130.
Trastuzumab is a monoclonal antibody that can be used for breast cancer that expresses the HER2 protein.
Atripla is an HIV medication that contains three separate medications that are beneficial in reducing viral load.
Rivaroxaban is an anticoagulant that may be commonly used in the management of stroke and deep vein thrombosis.
Fioricet is a combination of three medications. Butalbital, acetaminophen, and caffeine are the three ingredients in this medication.
Insulin detemir is a long-acting insulin analog that lowers blood sugar. This medication is used to target fasting blood sugars. -
On the top 200 drugs podcast, we cover 5 more medications. The medications covered on today's episode include; omalizumab, nitroglycerin, apixaban, gabapentin, and etanercept.
Omalizumab is a monoclonal antibody used in moderate to severe asthma. It targets IgE-mediated asthma attacks and reactions. Anaphylaxis is a significant concern with the use of this medication.
Sublingual nitroglycerin is frequently used on an as needed basis for angina symptoms. I discuss major drug interactions and much more.
Apixaban is an anticoagulant used to prevent stroke in atrial fibrillation. It can also be used in DVT/PE treatment and prevention.
Gabapentin is classified as an antiepileptic agent but is most commonly used for neuropathic type pain.
Etanercept targets TNF alpha which plays an important role in autoimmune diseases such as rheumatoid arthritis. -
In this episode of the Top 200 Drugs Podcast, I cover glyburide, citalopram, olmesratan, carvedilol, and tiotropium.
Glyburide is a sulfonylurea that is well known to cause hypoglycemia and weight gain because it stimulates the pancreas to increase insulin release.
Citalopram is an SSRI most well known for its potential to increase the risk for QTc prolongation. It has a notorious drug interaction with omeprazole
Olmesartan is an ARB that can be used for hypertension. Hyperkalemia is an electrolyte imbalance that can be caused by its use.
Carvedilol is one of the few beta-blockers with significant alpha-blocking and beta-blocking activity. I discuss what this means in this Top 200 drugs podcast.
Tiotropium is an anticholinergic medication that can open the airway. It is most commonly used for COPD. -
Clindamycin is an antibiotic for infection. It inhibits protein synthesis by binding to the 50s ribosomal subunit and is well known to contribute to C. Diff. risk.
Acetaminophen is a common over-the-counter medication that relieves pain and fever. It does not have much benefit in reducing inflammation, however.
Ferrous sulfate is a supplement that can be useful in treating anemia. Dark stools and constipation are two common adverse effects.
Eletriptan is a medication used to abort migraine headaches. It has serotonin action. I discuss the potential for interactions with other serotonergic medications.
Methocarbamol is an older skeletal muscle relaxant that makes an appearance on the Beers list as it can cause sedation, confusion, and increase the risk of falls. -
Zoledronic acid is a bisphosphonate that can be used to manage hypercalcemia of malignancy and osteoporosis.
Glipizide is an anti-diabetes agent that is classified as a sulfonylurea. Weight gain and hypoglycemia and two big concerns with this agent.
Lactulose is classified as a laxative but is more commonly used to reduce ammonia levels in hepatic encephalopathy.
Rabeprazole is a PPI used to reduce gastric acid secretions and improve conditions such as GERD, peptic ulcer disease, and Barrett's esophagus.
Methotrexate is classically grouped with oncology agents but is frequently used in autoimmune conditions like rheumatoid arthritis and Crohn's disease. -
On this episode of the Real Life Pharmacology podcast, we cover medications 101-105 of the top 200 drugs
Atomoxetine is a norepinephrine reuptake inhibitor that is used in the management of attention deficit hyperactivity disorder.
Zolpidem is a medication that is used for insomnia. It has a very similar adverse effect profile to benzodiazepines.
Advair is a commonly used respiratory medication for asthma. It is a combination of a long-acting beta agonist and inhaled corticosteroid.
Levofloxacin is a quinolone antibiotic that has a boxed warning for neuropathy, tendon rupture, and CNS adverse effects.
Imipramine is a tricyclic antidepressant that is highly anticholinergic. Dry eyes, dry mouth, constipation, urinary retention, sedation, and memory impairment are potential adverse effects. -
We have finally reached 100 of the top 200 drugs podcasts!
On this episode, we tackle methadone. This is a complex opioid used for opioid use disorder and may also be used for pain.
Enalapril is an ACE inhibitor that is used for hypertension. Cough and hyperkalemia are two major adverse effects to remember.
Oseltamivir is a neuraminidase inhibitor. In patients with poor renal function, we need to make sure to adjust the dose accordingly.
Ropinirole is a dopamine agonist. This medication is primarily used for restless leg syndrome but is also indicated for Parkinson's disease.
Penicillin VK is the original penicillin antibiotic. Common indications of this medication are strep throat, skin and soft tissue infections, and syphilis. -
On this episode of the Real Life Pharmacology Podcast, I cover 5 more medications of the top 200.
Fenofibrate is a medication used primarily to reduce triglycerides. This medication differs from statins which tend to focus on LDL management.
Doxazosin is an alpha-blocker. The primary indications of doxazosin are hypertension and BPH.
Naproxen is an NSAID. Of all the NSAIDs, naproxen is one of the lower-risk agents with regard to cardiovascular risk.
Spironolactone is an aldosterone antagonist and also classified as a potassium sparing diuretic.
Memantine is an NMDA antagonist that is indicated for the management of Alzheimer's dementia.
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On this episode of the Real Life Pharmacology podcast, we cover 5 more medications in the top 200.
Metronidazole is an antibiotic for infection. One of the most common complaints from patients involves reporting of a metallic taste in the mouth.
Levetiracetam is an anti-seizure medication. Sedation, dizziness, and other adverse effects of the central nervous system are the most common complications.
Colchicine is a gout medication. The most memorable side effect associated with this medication is diarrhea.
Olanzapine is an antipsychotic. Olanzapine carries a higher risk for metabolic syndrome compared to other antipsychotics.
Dutasteride is a 5 alpha-reductase inhibitor that is indicated for the treatment of BPH.
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On this episode of the Real Life Pharmacology podcast, I cover medications 81 through 85 on the top 200 drug list.
Famotidine is an H2 blocker. H2 blockers are less potent than PPIs but can be used to manage heartburn symptoms.
Aspirin is technically an NSAID but is primarily used for cardioprophylaxis purposes.
Senna is a stimulant laxative. I often see this medication used with opioids to help manage opioid-induced constipation.
Novolog is a rapid acting insulin used to bring down post prandial blood sugars. I discuss sliding scale insulin and other concepts with this medication.
Baclofen is a skeletal muscle relaxant. It has central nervous system depressant effects which can be especially problematic in elderly patients.
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Reglan (metoclopramide) is used for gastroparesis and inhibits gastric smooth muscle by blocking dopamine receptors.
Relafen (nabumetone) is a non-selective inhibition of COX-1/COX-2 which leads to a reduction of inflammation via reduced prostaglandins.
Keflex (cephalexin) is a 1st generation oral cephalosporin that covers common gram positive organisms like Staph and Strep species.
Effexor (Venlafaxine) is an SNRI and inhibits both serotonin and norepinephrine reuptake. Primary uses include anxiety and depression.
Boniva (ibandronate) inhibits osteoclasts which helps treat osteoporosis. Osteoclasts break down bone to help pull calcium into the bloodstream. -
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Robitussin (Guaifenesin) is a medication that is used as a cough suppressant. It is often combined with numerous other medications so patients need to pay attention
Valium (diazepam) is a benzodiazepine used to treat anxiety or seizures. Falls, dizziness, confusion, and sedation are common adverse effects.
Viagra (sildenafil) makes the list at number 73. This medication is a PDE-5 inhibitor that can be used for erectile dysfunction.
Bactroban (mupirocin) is a topical antibiotic that can be used for superficial skin infections.
Januvia (Sitagliptin) is a DPP4 inhibitor used for treating hyperglycemia in type 2 diabetes. It doesn't reduce A1C quite as much as other diabetes medications like SGLT2 inhibitors and GLP-1 agonists. -
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Pantoprazole (Protonix) is a PPI that can be used for GERD and peptic ulcer disease. I differentiate why this medication is different from the commonly used omeprazole.
Dicyclomine (Bentyl) is an anticholinergic medication that may be used to help reduce pain and spasms associated with irritable bowel syndrome.
Sumatriptan (Imitrex) is a selective 5HT1 receptor agonist, which potentially helps with vasoconstriction that contributes to migraine symptoms.
Chlorhexidine (Peridex) is an antibiotic oral rinse that can be used for gingivitis.
Metoprolol (Lopressor, Toprol XL) is a beta-blocker that may be used for atrial fibrillation, angina prevention, and hypertension. It is not a first-line medication for hypertension. -
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In this episode, we highlight some of the most important clinical pearls (and highly testable pearls) on the following medications; Suboxone, lisdexamfetamine, nortriptyline, insulin lispro, and valproic acid.
Suboxone is a combination of buprenorphine and naloxone used for opioid use disorder.
Lisdexamfetamine is a stimulant medication that can be used to manage ADHD. Common side effects include weight loss, insomnia, hypertension, and tachycardia.
Nortriptyline is a TCA medication known for its ability to cause anticholinergic side effects like constipation, dry eyes, dry mouth, urinary retention, and confusion.
Insulin lispro is a rapid-acting insulin medication that is most often used to bring down post-prandial blood sugar.
Valproic acid is an antiepileptic medication that can also be used for migraines. -
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In this episode, we highlight some of the most important clinical pearls on the following medications; nitrofurantoin, fentanyl patches, isosorbide mononitrate, fluoxetine, and triamcinolone.
Nitrofurantoin is an antibiotic used for UTIs. We need to be careful with this medication in patients with CKD.
Fentanyl is an opioid. There are many clinical quirks with fentanyl patches. For a full rundown, check out this previous podcast episode.
Isosorbide mononitrate is a nitrate medication so we need to be careful with the use of PDE-5 inhibitors.
Fluoxetine is an SSRI. It has a longer half-life than most SSRIs. I discuss what that means in this episode.
Triamcinolone (topical) is most frequently used for redness, itching, and skin irritation. -
On this episode of the Real Life Pharmacology podcast, I cover medications 51-55. They are eszopiclone, celecoxib, estrogen, moxifloxacin, and donepezil.
Eszopiclone is a "Z" drug used for insomnia. Its adverse effect profile is very similar to benzodiazepines.
Celecoxib is a COX-2 Inhibitor used for pain and inflammation. I discuss how this medication differs from traditional NSAIDs.
Estrogen therapy is used for menopausal symptoms but carries a risk of cancer and blood clots.
Moxifloxacin is a quinolone antibiotic. Binding drug interactions, boxed warnings, and QTc prolongation are potential concerns.
Donepezil is a medication used for dementia. I discuss its mechanism of action and common adverse effects. - Laat meer zien
