Afleveringen
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An interview with Dr Chloe Anthias, medical director of the new Cell Collection Centre has just opened by Anthony Nolan charity as part of our NIHR Nottingham Clinical Research Facility.
Links
a little while ago I talked to Prof Mark Bishton, whoâs an oncologist at the hospital about stem cell research. Listen here NIHR Nottingham Clinical Research Facility To find out more about the Anthony Nolan Cell Collection Centre, to donate to Anthony Nolan or to find out how to join the stem cell register, visit: www.anthonynolan.orgThis Podcast is brought to you by the NIHR Nottingham Clinical Research Facility. Follow us on @NottmCRF, or email Nottingham research.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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This bulletin intro was brought you by Harriet Anderson from Research and Innovation Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at â R&[email protected].ukâ .
Tags: #SAPhEStudy, #Nanopore #SequencerDevice, #Tech, #RoundTableTalks, #PRES #BrainTumor
Links
Nanopore - https://nottinghamcrf.nihr.ac.uk/about/news/nottingham-leads-the-way-dna-sequencing-technology-could-transform-brain-tumour-diagnosis Patient transfers - [email protected] Loughborough University round-table talks about dementia care and research - [email protected]. R&I Clinical support department showcase - [email protected] Participant research experience survey - https://sites.google.com/nihr.ac.uk/crneastmidspres/survey SAPhE study - [email protected].ukThis Podcast is brought to you by the â Research & Innovation team at Nottingham University Hospitals NHS Trustâ . Follow us on â @ResearchNUHâ and â @NottmBRCâ , or email â R&[email protected].ukâ .
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and
like/review us on Apple Podcasts or Spotify especially. It's For Science.
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Zijn er afleveringen die ontbreken?
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Asthma is one of the most common conditions - there are 8 million of us in the UK who suffer from it. t can range from the needing a quick puff on your inhaler if you exercise and thereâs a lot of pollen about it, to serious, fatal attacks, thereâs still a lot we donât know. Thatâs what this interview with our respiratory physician Matthew Martin is all about.
One of the things weâre not sure about is to do with how people with inhalers use them - short version, we might doing it all wrong, then again we might not, this is research after all - and thatâs what the second bit of the interview youâre about to hear covers.
More on the APEX trial: https://nottinghambrc.nihr.ac.uk/research/respiratory/airway-disease-theme
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This bulletin intro was brought to you by Ian Kingsbury from East Genomics Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at â R&[email protected].ukâ .
#BioResource, #GLADstudy, #NIHR, #Chest drains, #PneumocystisPneumonia, #NottinghamUniversityHospitals
Links
East Genomics â https://www.eastgenomics.nhs.uk/
Join the world's largest study of anxiety & depression - https://gladstudy.org.uk/
PCP â If you are interested in contributing to the development of this research proposal, please contact Vikki Flemming, Consultant Clinical Scientist, Clinical Microbiology, [email protected].uk
Chest drain - So If you, or someone you care for, has had a chest drain fitted as part of their treatment, please email: [email protected].uk
BioResource â bioresource.nihr.ac.uk or [email protected].uk
This Podcast is brought to you by the â Research & Innovation team at Nottingham University Hospitals NHS Trustâ . Follow us on â @ResearchNUHâ and â @NottmBRCâ , or email â R&[email protected].ukâ .
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.
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One of the fundamentals of clinical research is the âblindâ bit of the double-blind placebo controlled trial. If neither the researcher nor the participant know whether theyâre getting placebo or the drug, it removes the chances that theyâre unconsciously responding in the way they think they should.
The placebo effect can account for up to 30% of a difference, so it has to be dealt with.
But if youâre trialling a therapy where the patient will know whatâs going on - like exercise for rehab, for example - it canât be blind. So how do you get round that?
We spoke to clinical research physiotherapist Paul Matthews about the challenges he faced when he was studying exercise as part of rehab for broken ankles.
This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected].uk.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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The intro this week was from Harriet Anderson, who works in the Research and Innovation team at Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at R&[email protected].uk.
Links
Mental health citizen science - www.gladstudy.co.ukParticipant in Research Experience Survey - The results for NUH: https://www.nuh.nhs.uk/ri-feedback, and for people in the East Midlands: https://sites.google.com/nihr.ac.uk/crneastmidspres/survey NHS East Genomics - https://www.eastgenomics.nhs.uk/for-healthcare-professionals/genomic-tests/ Liver walks: email Abhishek Sheth [email protected] Centre for Rare Respiratory DiseasesWillow Tranter appeal - https://www.justgiving.com/page/willowsjourneywithall and Cure Leukaemia https://www.cureleukaemia.co.uk/ Babi study - https://www.babinetwork.co.uk/This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected].uk.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.
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Youâd think that clinical researchers would welcome surprises - but they donât. Even if the results are new and groundbreaking, they want their trials and studies to run in a predictable, controlled way,.
And that ability to deliver a total lack of surprise is one of the reasons that cancer research at Nottingham University Hospitals NHS Trust has made it into the top flight in the UK working with major pharmaceutical companies.
As well as clinical and scientific excellence, itâs about building up relationships with our partners so that we know we can deliver on recruiting patients, managing the pharmacy needs, and study set up.
The focus is particularly on chemo-free approach to lymphoma treatment, immunotherapy such as CAR T therapy, bispecific antibodies and using data analysis to target treatments.
I talked to Professor Mark Bishton, whoâs a consultant haemotologist and the divisional co-lead for research and innovation into cancer and associated. As well as his own research, heâs responsible for delivering the trustâs studies in the specialty.
More information at https://www.nuh.nhs.uk/research-in-cancerThis Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected].uk.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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Staff at the NIHR Nottingham Clinical Research Facility talk about the UCAB trial.
The facility worked with Swedish pharmaceutical Umecrime Cognition to study using a new molecule as a treatment for Primary Biliary Cholangitis (PBC) for patients with severe symptoms of fatigue and cognitive impairment.
Quick takeaways -
âą one of only two UK locations for first stage drug trial
âą kept to tight, complex timelines
âą exceeded recruitment targets by building on existing relationships
âą patients praised care and treatment
The NIHR Nottingham Clinical Research Facility (CRF) was one of just two centres worldwide â and the only UK facility â to conduct the first part of a clinical study.
We were picked because of our expertise in liver disease.
We hosted five patients on a purpose-built inpatient ward within the CRF, to confirm the correct dose of the molecule. During their seven-day stay, our team of research nurses and physicians assessed and cared for the patients around the clock.
Nottingham CRF has 18 adult and five paediatric inpatient beds dedicated for research, alongside our dedicated outpatient and specialist clinics. In total, there is over 3,400mÂČ of clinical space at our CRF. The PBC study was a randomised, double-blinded and placebo controlled two-part study to evaluate the pharmacokinetics, safety and tolerability, and preliminary efficacy of two dose levels of the new drug.
Thereâs more about it at https://nottinghamcrf.nihr.ac.uk/facilities/case-studies
Follow us on Twitter: @NottmBRC
Follow us on Instagram: @NottmHealthScience
Follow us on Facebook: https://www.facebook.com/ResearchNottingham
Watch a video explainer about clinical trials: https://youtu.be/SWS4FCSMWAQ
Read more at https://www.nottinghamresearch.org/get-involved and https://www.nuh.nhs.uk/take-part-in-a-trial and https://www.nuh.nhs.uk/researchvolunteers
Email us at [email protected].uk
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Contacts for his episode:
COACH trial for hearing aids vs cochlear implants - More information from coachtrial.ac.uk or email [email protected] Ultrasound probe for people with trauma injuries - contact Georgia Melia at [email protected] The studies in Norfolk and Leicester into communities and genomics - www.eastgenomics.nhs.uk or email the East Genomic Medicine Service Alliance (GMSA) at [email protected] The Healthcare Scientists Research Showcase tickets are at https://www.eventbrite.co.uk/e/healthcare-scientists-research-showcase-tickets-835899837917
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Bulletin 9 - developing treatments for cystic fibrosis, depression, alcoholic liver disease and eczema
In this episode:
We pick up on presentations from the NIHR Nottingham BRC conference, from:
Dr Helen Barr, on matching medicines to gene for CF patients Prof Richard Morriss on treating depression and anxiety with transcranial magnetic stimulation - https://www.mindtech.org.uk/news-events/latest-news/brightmind-trial-improves-the-lasting-effects-of-treatment-for-severe-depression A Q and A on alcoholic liver disease - https://youtu.be/orJBGWAo8fM Finding out how often should you shower if you eczema - rapideczematrials.org/eczema-bathing-studyOur YouTube channel: @NottinghamClinicalResearch
This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected].uk.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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In this bulletin:
Testing the Respirasense breathing monitor from PMD Solutions - https://www.pmd-solutions.com - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3944-respirasense-trial Bone graft augmentation and gene therapy research with Theragenix - https://theragenix.health/https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3942-nearly-1m-for-pioneering-gene-therapy-formulation-for-bone-graft-augmentation
Rib fracture pain relief - https://orif.octru.ox.ac.uk/https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3949-can-innovative-surgery-cut-mortality-after-major-trauma-injuries
Medicine showcases Clinical Academie Research Partnership awards - https://www.nihr.ac.uk/documents/clinical-academic-research-partnership-carp/30439 Robot urology surgery to lessen erectile dysfunction - https://www.theurologyfoundation.org/get-involved/urology-awareness-month -
In this bulletin:
Secure Data Environments - â https://transform.england.nhs.uk/key-tools-and-info/data-saves-lives/secure-data-environments/â Prof Guru Aithal appointed new medical lead for the Eastern Genomic Medicine Service Alliance - â https://www.eastgenomics.nhs.uk Showcase of gastro intestinal research at Nottinghamâ Meet the respiratory research team - with pizzas Networking for early career imaging researchersIf you want to stay up to day with the clinical research podcast, you can find us on iTunes, Spotify, Google and where-ever you normally get your podcasts. The more shows are rated and reviewed, the easier it is for search engines to find us, so if you can subscribe and rate and review us, you'll be doing it for science.
This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected], or visit nuh.nhs.uk/research for more information.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially.
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Links to show items
Equity in Doctoral Education through Partnership and Innovation programme - https://www.ntu.ac.uk/c/equity-in-doctoral-education-through-partnership-and-innovation MRI PhDs - https://www.nottingham.ac.uk/research/beacons-of-excellence/precision-imaging/current-opportunities/studentships/nihr-nottingham-brc/index.aspx AERIFY study - https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/aerify-3/ AMAS report - https://acmedsci.ac.uk/policy/policy-projects/future-proofing-uk-health-research AMAS video - https://youtu.be/tWduBG3XSBE QGenome - https://www.eastgenomics.nhs.uk/about-us/news-and-events/launch-of-qgenome-across-the-east-gmsa/ Roman Foundation - https://theromefoundation.org/rome-foundation-fellows/rome-foundation-fellows-2023/ CRF conference registration - https://meetinnottingham.bzon.uk/ukcrf23-registration/ Research Excellence Awards - https://www.nuh.nhs.uk/research-excellence-awards-2023This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected].uk.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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Spend an evening with blood, urine, saliva and Nottingham researchers, looking to the future of research at NUH, helping children andyoung people with mental crises, and how to show a researcher you love them.
Links:
BioResource event booking - https://www.eventbrite.com/e/574447577167 NUH medical director Keith Girling on why the Nottingham BioResource is good for patients â https://youtu.be/AC49MnM_CtY Previous podcast with Natasha Hill, Nottingham bioresource manager - https://youtu.be/bQJ0S4l7uF8 SaPHE study explained - https://youtu.be/ldtPG21slEo Book tickets to the SaPHE study even - https://www.eventbrite.co.uk/e/the-saphe-study-disseminationcelebration-event-tickets-549208496397 SaPHE study website - sites.google.com/nihr.ac.uk/saphepathway/home NIHR Nottingham Clinical Research Facility â www.nottinghamcrf.nihr.ac.uk NUH medical director Keith Girling on talks about the CRF video - https://youtu.be/DWre8K7z4NQ UK CRF conference Registration - https://meetinnottingham.bzon.uk/ukcrf23-registration/ Staff awards - https://www.nuh.nhs.uk/research-excellence-awards-2023Download a transcript of this episode.
This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&[email protected].uk.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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In this clinical research bulletin from Nottingham:
Notts County legend Les Bradd has been helping our researchers investigating football-related injuries. https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3927-notts-county-fc-legend-les-is-helping-researchers-investigating-playing-injuries We hit national and international headlines this week for study which identified 500 genes linked to lung healthhttps://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3932-nottingham-researchers-lead-gene-study-to-enable-personalised-lung-health-care a review of Covid treatments for vulnerable people in Nottingham showed that being white, female and better-off, meant you were more likely to acceptcovid-19 treatment https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3930-white-female-better-off-vulnerable-patients-more-likely-to-accept-covid-19-treatment-nottingham-study-shows If you fancy spending an evening discussing the possible uses of blood, urine, saliva and body tissue, together with their related health data, then we have an online event youâll love - https://www.eventbrite.com/e/574447577167If you want to stay up to day with the clinical research podcast, you can find us on iTunes, Spotify, Google and where-ever you normally get your podcasts. The more shows are rated and reviewed, the easier it is for search engines to find us, so if you can subscribe and rate and review us, you'll be doing it for science.
This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC or email R&[email protected], or visit nuh.nhs.uk/research for more information.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially.
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In this episode - clinical research news of ASSIST MS study, World Hearing Day, NIHR researcher appointments, Liver Partnership launch, and the Tummy Tracker app for cystic fibrosis patients.
Links
ASSIST-MS - https://www.nihr.ac.uk/news/ground-breaking-ai-research-aims-to-improve-tests-and-treatments-for-thousands-of-patients/32852 World Hearing Day - https://worldhearingday.org/ Nottingham partnership - 3925-people-living-with-dementia-and-hearing-conditions-invited-to-shape-future-research Prof Morriss reconfirmed - https://arc-em.nihr.ac.uk/news-events/news/arc-east-midlands-theme-lead-reappointed-nihr-senior-investigator NIHR Nottingham BRC Mental Health and Technology researchers -https://nottinghambrc.nihr.ac.uk/research/mental-health-technology/mental-health-technology-team NIHR Nottingham BRC leadership team - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/leadership-team KLIFAD open access registration - https://bmjopen.bmj.com/content/bmjopen/11/11/e054954.full.pdf Dr Subhani talks about the Liver Partnership - https://youtu.be/7BZEB6VbeHQ NIHR Nottingham BRC Gastrointestinal & Liver team https://nottinghambrc.nihr.ac.uk/research/gastrointestinal-liver/gastrointestinal-liver-team CF Tummytracker app - https://cftummytracker.orgThis Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUHand @NottmBRC, or email R&[email protected], or visit nuh.nhs.uk/researchfor more information.
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Weekly updates from research and innovation team at Nottingham University Hospitals NHS Trust and NIHR Nottingham Biomedical Research Centre
Links
Methotrexate study - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3925-methotrexate-study Tinnitus research - https://www.mdpi.com/2076-3425/12/4/484 PrAISED study - Video - https://youtu.be/VB6GET95Sgg - https://www.nottingham.ac.uk/research/groups/healthofolderpeople/projects/praised/ University of Nottingham respiratory research professorship application - https://jobs.nottingham.ac.uk/vacancy.aspx?ref=MED630022 CARP research grants - https://www.nihr.ac.uk/documents/clinical-academic-research-partnerships-carp/30439 BRAID breast cancer study - https://www.nottingham.ac.uk/research/groups/nottinghambreastcancerresearchcentre/index.aspxMore information about research and innovation in general at Nottingham on the Nottingham University Hospital NHS Trust website which is www.nuh.nhs.uk/research, and about the NIHR Nottingham Biomedical Research Centre on our website, which is at nottinghambrc.ac.uk - and ourr email and social media links are there too.
If you want to stay up to day with the clinical research podcast, you can find us on iTunes, Spotify, Google and where-ever you normally get your podcasts. The more shows are rated and reviewed, the easier it is for search engines to find us, so if you can subscribe and rate and review us, you'll be doing it for science.
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Weâve launched a new podcast, itâs a short update on research in Nottingham, and itâs for both researchers and anyone interested in clinical research and itâs out every fortnight.
The first episode covers the Nottingham methotrexate study which has piqued worldwide interest and sparked tens of thousands of tweets, as well as research into dementia, tinnitus and breast cancer. Weâve also got details of grants, job vacancies and other support for researchers.
If youâre already subscribed to the Nottingham Clinical Research podcast, itâll show up in your feed without you doing anything at all. If youâre not, search for Nottingham Clinical Research where-ever you normally get your podcast.
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As the NIHR Nottingham Biomedical Research Centre embarks on its second tranche of funding, we're developing our existing partnerships with other clinical research organisations in the East Midlands, especially Nottingham Trent University.
One of our closest links there is Professor John Hunt, who's Head of NTU's medical technologies and advanced materials research theme. He's also just taken on a role as deputy director of the NIHR Nottingham Clinical Research Facility, based at Nottingham University Hospitals NHS Trust.
I talked to him about his own research in clinical sciences, and particularly biomaterials, as well as his new role at the clinical research facility
Links
NIHR Nottingham Biomedical Research Centre NIHR Nottingham Clinical Research Facility NTU's Medical Technologies Innovation FacilityThis Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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Chronic lung diseases are the third biggest cause of death in the world, and in Nottinghamshire, about 1 in 8 people have been diagnosed with asthma or COPD - so finding new treatments is high on the list for clinical researchers. And our particular expertise here is understanding how the disease works at a cellular level and it's why we're part of new ÂŁ8.8million study funded by the Wellcome Trust.
But environmental factors - like smoking, or working down a mine - are only part of the story. Genetic make up means some people are more at risk than others, and this study is about understanding how we can detect who's more likely to develop lung disease.
It's being led here by Nottingham University Hospitals NHS Trust respiratory consultant Professor Ian Hall, who's also the director of the NIHR Nottingham Biomedical Research Centre.
Read more about the announcement here.
This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research.
If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.
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